Streptomyces cathayae: PYS65_27000
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Entry
PYS65_27000 CDS
T09946
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scay
Streptomyces cathayae
Pathway
scay00300
Lysine biosynthesis
scay00550
Peptidoglycan biosynthesis
scay01100
Metabolic pathways
scay01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scay00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PYS65_27000 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PYS65_27000 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PYS65_27000 (murF)
Enzymes [BR:
scay01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PYS65_27000 (murF)
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Paralog
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DHHA1
DUF561
DUF2126
Motif
Other DBs
NCBI-ProteinID:
WGD43484
LinkDB
All DBs
Position
5919202..5920632
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AA seq
476 aa
AA seq
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MIALSLAEIAEVVGGQTYDIPDPSVQVTGGVVRDSREAGPGSLFVAFVGEHVDGHDFAAA
VVEAGAAAVLGSRPVGVPAIVVDDVQRALGALARHVVQRLGATLVALTGSSGKTSTKDLI
AQVLRRKAPTVFTPGSLNNEIGLPLTALTATEETKFLVLEMGARGIGHIRYLTDLTPPKV
GLVLNVGTSHIGEFGGRAQIAQAKGEMVEALPPAEEGGTAILNADDPLVRAMASRTKAKV
LLFGETDEADVRAENVRLTDSGQPSFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSAEEIALALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGKASQ
AKGGRTWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREAAWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRQGDVVLVKASRSVGLESVAQALLATGTEGEVVTR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgaagtcgtcggcgggcagacgtacgacata
ccggatccgtccgtccaggtcaccggaggtgtcgtccgggactcgcgggaagcgggtccc
ggcagcctcttcgtcgccttcgtcggcgaacacgtggacggccacgacttcgcggccgcg
gtcgtcgaggcgggcgcggccgccgtgctcggctcccgccccgtgggcgtgcccgcgatc
gtcgtcgacgacgtccagagagcgctgggcgccctcgcccggcacgtcgtgcagcgcctc
ggcgcgaccctcgtcgcgctcaccggctcgtccggcaagaccagcaccaaggacctcatc
gcgcaggtgctgcggcgcaaggcgcccaccgtcttcacccccggatccctcaacaacgag
atcgggctgccgctgaccgcgctcaccgctaccgaggagacgaagttcctcgtgctggag
atgggtgcccgcgggatcggccacatccgctacctcaccgacctgacgcccccgaaggtc
ggtctggtcctcaacgtcggcacctcccacatcggcgagttcggcggccgggcgcagatc
gcccaggccaagggcgagatggtggaggccctgccgccggccgaggagggcggcaccgcg
atcctcaacgcggacgacccgctcgtacgcgccatggcgtcccgtacgaaggcgaaggtg
ctccttttcggagagaccgacgaagcggacgttcgggccgagaacgtgcgactcacggac
agcggacagccctcgttcaggcttcacacaccctccggtgcaagcgatgtgaccatgcgc
ctgtacggtgagcatcacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgagttg
ggcatgtccgcagaagagattgcactcgcgctctccgaggcgggctccctctcccgctgg
cggatggaggtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagccgccctgcgcgcgctcgcggccatgggcaaagcctcacag
gcgaaggggggtcgtacgtgggcggtgctcggcaagatggccgagctcggggacgaggcg
ctcgccgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gcggtcgggggcagggaagccgcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcacaggcggctgtcgacctgttgcgcagtgaa
ttgcgccagggagacgtcgttctcgtgaaggcgtcccgttcggtcggtctcgagagcgtg
gcgcaggcgctgctcgcgaccggtaccgagggtgaggtcgtcacccgatga
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