Streptomyces scabiei: SCAB_26871
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Entry
SCAB_26871 CDS
T01187
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
scb
Streptomyces scabiei
Pathway
scb00290
Valine, leucine and isoleucine biosynthesis
scb00620
Pyruvate metabolism
scb01100
Metabolic pathways
scb01110
Biosynthesis of secondary metabolites
scb01210
2-Oxocarboxylic acid metabolism
scb01230
Biosynthesis of amino acids
Module
scb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
scb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SCAB_26871
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SCAB_26871
Enzymes [BR:
scb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SCAB_26871
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
CBG69790
UniProt:
C9Z581
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All DBs
Position
complement(3057881..3059485)
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AA seq
534 aa
AA seq
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MTETSELDDSFHVFDTTLRDGAQREGINLTVADKLAIARHLDDFGVGFIEGGWPGANPRD
TEFFARAQKEIDFRHAQLVAFGATRRAGGRASEDPQVKALLDSGAPVITLVAKSHDRHVE
LALRTTLDENLEMVRDTVSHLRAQGRRVFVDCEHFFDGYRANPEYAKAVVRTASEAGADV
VILCDTNGGMLPAQVQAVVATVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTA
NGYGERVGNANLFPVVAALELKYGKKVLPDGRLRDMTRISHAIAEVVNLTPSTHQPYVGV
SAFAHKAGLHASAIKVDPDLYQHIDPEQVGNTMRMLVSDMAGRASIELKGKELGVDLGDD
RELVGRVVERVKERELKGYTYEAADASFEILLRDEVAGKPQRYFRTESWRAIVEDRPDGS
HANEATVKLWSRSERIVATAEGNGPVNALDRALRVALEKIYPQLAKLELVDYKVRILEGK
HGTNSTTRVLISTTDGTGEWSTVGVADNVIAASWQALEDAYTYGLLRAGVEPAE
NT seq
1605 nt
NT seq
+upstream
nt +downstream
nt
atgacggaaaccagcgaactcgacgactcgttccacgtcttcgacaccaccctgcgcgac
ggcgcccagcgtgagggcatcaacctcacggtcgcggacaagctggccatcgcacggcac
ctggacgacttcggcgtcggcttcatcgagggcggctggcccggtgcgaacccgcgcgac
accgagttcttcgcccgcgcccagaaggagatcgacttccggcacgcccagctggtcgcg
ttcggcgccacccgccgcgctggtggcagggcgagcgaggacccgcaggtcaaggccctg
ctcgactccggcgcgccggtgatcaccctggtcgccaagtcccacgaccgtcatgtggaa
ctggccctgcgcaccaccctcgacgagaacctggagatggtccgcgacaccgtctcccac
ctgcgcgcgcagggccgccgggtcttcgtcgactgcgagcacttcttcgacggctaccgc
gccaaccccgagtacgccaaggccgtcgtccgcaccgcctccgaggccggcgccgacgtc
gtgatcctctgcgacaccaacggcggcatgctgccggcccaggtccaggccgtcgtcgcc
accgtcctcgccgacacgggcgcccgcctcggcatccacgcccaggacgacaccggctgc
gcggtcgccaacaccctggccgccgtcgacgccggcgccacccacgtccagtgcaccgcc
aacggctacggcgagcgcgtcggcaacgccaacctcttcccggtcgtcgccgccctggaa
ctgaagtacggcaagaaggtcctccccgacggccgcctgcgcgacatgacccgcatctcg
cacgccatcgccgaggtcgtcaacctcaccccctccacccaccagccgtacgtcggtgtc
tccgccttcgcgcacaaggccggcctgcacgcctccgcgatcaaggtcgacccggacctg
taccagcacatcgaccccgagcaggtcggcaacaccatgcggatgctcgtctccgacatg
gcgggccgcgcctccatcgagctcaagggcaaggagctgggcgtcgacctcggcgacgac
cgcgagctggtgggccgggtcgtcgagcgggtcaaggagcgcgaactcaagggctacacc
tacgaggccgccgacgcgagcttcgagatcctgctgcgcgacgaggtcgcgggcaagccg
cagcggtacttccgcaccgagtcatggcgggccatcgtcgaggaccgccccgacggcagc
cacgccaacgaggccaccgtcaagctgtggtccaggagcgagcgcatcgtcgccacggcc
gagggcaacggcccggtcaacgccctcgaccgcgccctgcgggtcgccctggagaagatc
tacccccagctcgccaagctggagctggtcgactacaaggtgcgcatcctggagggcaag
cacggcaccaactccacgacccgcgtcctcatctccacgacggacggcacgggcgagtgg
tccacggtcggggtcgccgacaacgtgatcgccgcgtcgtggcaggcgctggaggacgcc
tacacgtacgggctgctgcgggcgggtgtggaaccggcggagtga
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