Streptomyces scabiei: SCAB_61851
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Entry
SCAB_61851 CDS
T01187
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
scb
Streptomyces scabiei
Pathway
scb00290
Valine, leucine and isoleucine biosynthesis
scb00620
Pyruvate metabolism
scb01100
Metabolic pathways
scb01110
Biosynthesis of secondary metabolites
scb01210
2-Oxocarboxylic acid metabolism
scb01230
Biosynthesis of amino acids
Module
scb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
scb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SCAB_61851 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SCAB_61851 (leuA)
Enzymes [BR:
scb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SCAB_61851 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
CBG73206
UniProt:
C9ZAQ8
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All DBs
Position
6848386..6850107
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AA seq
573 aa
AA seq
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MANRQQPTSMPIHKYGQYDQVDIPDRTWPNNRITVAPRWLSTDLRDGNQSLIDPMSPERK
RRMFDQLVKMGYKEIEVGFPASGQTDFDFVRSIIEEPGVIPDDVTISVLTQAREDLIERT
VESLKGAKRATVHLYNATAPVFRRVVFRGSKDDIKQIAVDGTRLVMEYAEKLLGPETEFG
YQYSPEIFTDTELDFALEVCEAVMDVWQPGPGREIILNLPATVERSTPSTHADRFEWMGR
NISRREHVCISIHPHNDRGTAVAAAELALMAGADRVEGCLFGQGERTGNVDLVTLGMNLF
SQGVDPQIDFSDIDEIRRTWEYCNQMEVHPRHPYVGDLVYTSFSGSHQDAIKKGFDAMEA
SAKEQGKTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLKNDHKLDLPRR
MQIEFSKLIQAKTDAEGGEVTGSDIWAVFQDEYLPNPDNPWGRVQVRNNQSTTDKDGVDT
LTVEAEVDGAPTTLVGTGNGPISAFFDALQGVGIDARLLDYQEHTMSEGASAQAASYIEV
AIEDKVLWGIGIDANTTRASLKAVVSAVNRAAR
NT seq
1722 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaccgccagcagcccacgtccatgccgatccacaagtacgggcagtacgaccag
gtcgacatcccggaccgcacgtggccgaacaaccggatcaccgtcgccccccgctggctc
tccaccgacctgcgcgacggcaaccagtccctgatcgacccgatgtcgcccgagcgcaag
cgccggatgttcgaccagctggtcaagatgggctacaaggagatcgaggtcggcttcccc
gcctccggccagacggacttcgacttcgtacggtcgatcatcgaggagccgggcgtcatc
ccggacgacgtcaccatctccgtcctgacccaggcccgtgaggacctgatcgagcggacc
gtggagtcgctgaagggcgccaagcgggcgaccgtccacctgtacaacgcgaccgccccc
gtcttccgccgggtcgtcttccggggttccaaggacgacatcaagcagatcgcggtggac
ggcacgcggctggtgatggagtacgccgagaaactgctgggccccgagaccgagttcggc
taccagtacagccccgagatcttcaccgacaccgagctggacttcgcgctggaggtctgc
gaggcggtcatggacgtctggcagcccggtccgggccgcgagatcatcctcaacctgccc
gccacggtggagcgttcgaccccgtccacgcacgcggaccgcttcgagtggatggggcgc
aacatctcccgccgcgagcacgtctgcatctccatccacccgcacaacgaccgcggtacg
gccgtcgcggcggccgaactggcgctgatggccggcgccgaccgcgtcgagggctgtctg
ttcggccagggcgagcgcaccggcaacgtcgacctggtcaccctgggcatgaacctgttc
tcgcagggcgtcgacccgcagatcgacttctccgacatcgacgagatccgtcgcacgtgg
gagtactgcaaccagatggaggtccacccgcgccacccgtacgtgggcgacctggtctac
acgtccttctccggctcccaccaggacgccatcaagaagggcttcgacgccatggaggcg
tccgcgaaggagcaggggaagacggtcgacgacatcgagtgggccgtgccgtacctgccg
atcgaccccaaggacgtcggccgctcctacgaggccgtcatccgggtcaactcgcagtcc
ggcaagggcggtatcgcctacgtcctgaagaacgaccacaagctggacctgccgcgccgg
atgcagatcgagttctcgaagctgatccaggccaagaccgacgccgagggcggcgaggtc
accggctccgacatctgggccgtcttccaggacgagtacctgccgaaccccgacaacccg
tggggccgggtccaggtccgcaacaaccagtcgaccaccgacaaggacggcgtggacacg
ctgaccgtggaggccgaggtcgacggcgcgccgaccaccctggtcggcaccggcaacggc
ccgatctccgcgttcttcgacgcgctgcagggcgtcggcatcgacgcacggctgctggac
taccaggagcacacgatgagcgagggcgcctccgcgcaggccgcctcgtacatcgaggtc
gccatcgaggacaaggttctgtggggcatcggtatcgacgcgaacacgacgcgtgcgtcg
ctgaaggcggtcgtctccgccgtcaaccgagcggctcgctga
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