KEGG   Streptomyces scabiei: SCAB_61851
Entry
SCAB_61851        CDS       T01187                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
scb  Streptomyces scabiei
Pathway
scb00290  Valine, leucine and isoleucine biosynthesis
scb00620  Pyruvate metabolism
scb01100  Metabolic pathways
scb01110  Biosynthesis of secondary metabolites
scb01210  2-Oxocarboxylic acid metabolism
scb01230  Biosynthesis of amino acids
Module
scb_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:scb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    SCAB_61851 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SCAB_61851 (leuA)
Enzymes [BR:scb01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     SCAB_61851 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: CBG73206
UniProt: C9ZAQ8
LinkDB
Position
6848386..6850107
AA seq 573 aa
MANRQQPTSMPIHKYGQYDQVDIPDRTWPNNRITVAPRWLSTDLRDGNQSLIDPMSPERK
RRMFDQLVKMGYKEIEVGFPASGQTDFDFVRSIIEEPGVIPDDVTISVLTQAREDLIERT
VESLKGAKRATVHLYNATAPVFRRVVFRGSKDDIKQIAVDGTRLVMEYAEKLLGPETEFG
YQYSPEIFTDTELDFALEVCEAVMDVWQPGPGREIILNLPATVERSTPSTHADRFEWMGR
NISRREHVCISIHPHNDRGTAVAAAELALMAGADRVEGCLFGQGERTGNVDLVTLGMNLF
SQGVDPQIDFSDIDEIRRTWEYCNQMEVHPRHPYVGDLVYTSFSGSHQDAIKKGFDAMEA
SAKEQGKTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLKNDHKLDLPRR
MQIEFSKLIQAKTDAEGGEVTGSDIWAVFQDEYLPNPDNPWGRVQVRNNQSTTDKDGVDT
LTVEAEVDGAPTTLVGTGNGPISAFFDALQGVGIDARLLDYQEHTMSEGASAQAASYIEV
AIEDKVLWGIGIDANTTRASLKAVVSAVNRAAR
NT seq 1722 nt   +upstreamnt  +downstreamnt
atggcgaaccgccagcagcccacgtccatgccgatccacaagtacgggcagtacgaccag
gtcgacatcccggaccgcacgtggccgaacaaccggatcaccgtcgccccccgctggctc
tccaccgacctgcgcgacggcaaccagtccctgatcgacccgatgtcgcccgagcgcaag
cgccggatgttcgaccagctggtcaagatgggctacaaggagatcgaggtcggcttcccc
gcctccggccagacggacttcgacttcgtacggtcgatcatcgaggagccgggcgtcatc
ccggacgacgtcaccatctccgtcctgacccaggcccgtgaggacctgatcgagcggacc
gtggagtcgctgaagggcgccaagcgggcgaccgtccacctgtacaacgcgaccgccccc
gtcttccgccgggtcgtcttccggggttccaaggacgacatcaagcagatcgcggtggac
ggcacgcggctggtgatggagtacgccgagaaactgctgggccccgagaccgagttcggc
taccagtacagccccgagatcttcaccgacaccgagctggacttcgcgctggaggtctgc
gaggcggtcatggacgtctggcagcccggtccgggccgcgagatcatcctcaacctgccc
gccacggtggagcgttcgaccccgtccacgcacgcggaccgcttcgagtggatggggcgc
aacatctcccgccgcgagcacgtctgcatctccatccacccgcacaacgaccgcggtacg
gccgtcgcggcggccgaactggcgctgatggccggcgccgaccgcgtcgagggctgtctg
ttcggccagggcgagcgcaccggcaacgtcgacctggtcaccctgggcatgaacctgttc
tcgcagggcgtcgacccgcagatcgacttctccgacatcgacgagatccgtcgcacgtgg
gagtactgcaaccagatggaggtccacccgcgccacccgtacgtgggcgacctggtctac
acgtccttctccggctcccaccaggacgccatcaagaagggcttcgacgccatggaggcg
tccgcgaaggagcaggggaagacggtcgacgacatcgagtgggccgtgccgtacctgccg
atcgaccccaaggacgtcggccgctcctacgaggccgtcatccgggtcaactcgcagtcc
ggcaagggcggtatcgcctacgtcctgaagaacgaccacaagctggacctgccgcgccgg
atgcagatcgagttctcgaagctgatccaggccaagaccgacgccgagggcggcgaggtc
accggctccgacatctgggccgtcttccaggacgagtacctgccgaaccccgacaacccg
tggggccgggtccaggtccgcaacaaccagtcgaccaccgacaaggacggcgtggacacg
ctgaccgtggaggccgaggtcgacggcgcgccgaccaccctggtcggcaccggcaacggc
ccgatctccgcgttcttcgacgcgctgcagggcgtcggcatcgacgcacggctgctggac
taccaggagcacacgatgagcgagggcgcctccgcgcaggccgcctcgtacatcgaggtc
gccatcgaggacaaggttctgtggggcatcggtatcgacgcgaacacgacgcgtgcgtcg
ctgaaggcggtcgtctccgccgtcaaccgagcggctcgctga

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