KEGG T00005: YDR232W

Saccharomyces cerevisiae (budding yeast): YDR232W

Entry

YDR232W           CDS       T00005

Symbol

HEM1, CYD1, OLE3

Name

(RefSeq) 5-aminolevulinate synthase

K00643

5-aminolevulinate synthase [EC:2.3.1.37]

Organism

sce Saccharomyces cerevisiae (budding yeast)

Pathway

sce00260

Glycine, serine and threonine metabolism

sce00860

Porphyrin metabolism

sce01100

Metabolic pathways

sce01110

Biosynthesis of secondary metabolites

sce01240

Biosynthesis of cofactors

Module

sce_M00868

Heme biosynthesis, animals and fungi, glycine => heme

Brite

KEGG Orthology (KO) [BR:sce00001]
09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    YDR232W (HEM1)
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    YDR232W (HEM1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:sce01007]
    YDR232W (HEM1)
Enzymes [BR:sce01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.37  5-aminolevulinate synthase
     YDR232W (HEM1)
Amino acid related enzymes [BR:sce01007]
Aminotransferase (transaminase)
  Class II
   YDR232W (HEM1)

SSDB

Motif

Pfam:

Aminotran_1_2 Cys_Met_Meta_PP Aminotran_5 DegT_DnrJ_EryC1

Other DBs

NCBI-GeneID:

851818

NCBI-ProteinID:

NP_010518

SGD:	S000002640

UniProt:

P09950

Structure

LinkDB

Position

IV:927452..929098

AA seq 548 aa
MQRSIFARFGNSSAAVSTLNRLSTTAAPHAKNGYATATGAGAAAATATASSTHAAAAAAA
AANHSTQESGFDYEGLIDSELQKKRLDKSYRYFNNINRLAKEFPLAHRQREADKVTVWCS
NDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFS
SCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQS
YPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHC
DFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFA
PGFIFTTTLPPSVMAGATAAIRYQRCHIDLRTSQQKHTMYVKKAFHELGIPVIPNPSHIV
PVLIGNADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAV
DDVFNELQLPRVRDWESQGGLLGVGESGFVEESNLWTSSQLSLTNDDLNPNVRDPIVKQL
EVSSGIKQ

NT seq 1647 nt +upstreamnt +downstreamnt
atgcaacgctccatttttgcgaggttcggtaactcctctgccgctgtttccacactgaat
aggctgtccacgacagccgcaccacatgcgaaaaatggctatgccaccgctactggtgct
ggtgccgctgctgccactgccacagcgtcatcaacacatgcagcagcagcagcagccgct
gctgccaaccattccacccaggagtcgggtttcgattacgaaggcctgatagattccgaa
ctgcagaagaaaagacttgacaaatcgtacagatatttcaacaatatcaaccgattggcc
aaggagttccccctagctcatcgccagagagaggcggacaaggtcaccgtttggtgttcc
aacgactatttagcactttccaagcaccctgaggtattggacgccatgcataaaactatc
gacaagtatggttgtggtgccggtggtacaagaaacattgctggccataacatccccact
ttgaatctggaagccgaattggccactttacacaagaaggaaggtgccttagttttttcg
tcatgttacgtagccaacgatgccgtcttatccctactgggtcaaaagatgaaggacttg
gtgattttctccgacgaactcaaccatgcgtccatgattgtcggtattaagcatgctaac
gtaaaaaaacacattttcaaacataatgacttgaacgaattggaacaactgctccagtca
taccccaaatccgttcctaaactaattgctttcgaatcagtatattctatggccggttca
gtggccgacatagaaaaaatttgcgacttggccgacaaatacggtgctttgaccttcttg
gatgaagtacatgcggtcggcctgtacggccctcacggtgcaggtgttgcagaacattgt
gattttgaaagtcaccgtgcaagtggtattgctaccccaaagaccaatgacaagggcggc
gcgaagactgtgatggaccgtgtcgacatgatcaccggcactttaggtaagtctttcggt
agcgtaggtggctacgtcgcagcctctaggaaattgatcgattggttcagatcgtttgca
cctggtttcattttcaccacgactttaccaccttcagttatggcaggcgctaccgcagca
attagataccaacgttgccacatcgacctaagaacctcgcaacagaaacataccatgtac
gtaaagaaagctttccatgagttgggcattccagttattccaaatccttctcatatcgtc
ccagtgttgattggtaatgctgatttggctaagcaagcttctgacatcttaatcaataag
catcaaatctacgtacaagctatcaacttccctacggttgctcgcggtaccgaaagattg
agaattaccccaacgccaggtcacaccaacgatttatctgacatcttaatcaatgcagtt
gatgatgtgttcaatgagctacagttaccacgtgtcagagactgggaaagccaaggtggc
ttattgggtgttggagagagcggatttgtggaagagtctaacttatggacatcaagccaa
ctatctttaactaatgacgacttgaaccctaatgttagagaccccatcgttaaacaacta
gaggtttctagtggtatcaagcagtaa

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