Saccharomyces cerevisiae (budding yeast): YDR457W
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Entry
YDR457W CDS
T00005
Symbol
TOM1
Name
(RefSeq) E3 ubiquitin-protein ligase TOM1
KO
K10592
E3 ubiquitin-protein ligase HUWE1 [EC:
2.3.2.26
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce04120
Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
YDR457W (TOM1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
sce04121
]
YDR457W (TOM1)
Enzymes [BR:
sce01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
YDR457W (TOM1)
Ubiquitin system [BR:
sce04121
]
Ubiquitin ligases (E3)
HECT type E3
YDR457W (TOM1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
DUF908
DUF913
UBM
ARM_ARMC5
Motif
Other DBs
NCBI-GeneID:
852068
NCBI-ProteinID:
NP_010745
SGD:
S000002865
UniProt:
Q03280
LinkDB
All DBs
Position
IV:1369790..1379596
Genome browser
AA seq
3268 aa
AA seq
DB search
MVLFTRCEKARKEKLAAGYKPLVDYLIDCDTPTFLERIEAIQEWDRSRDDLYVWIPILDR
MDGLLLKVAEKYKYKQDPKKECEVKLVEMEAHDVDYCLKMLKFTRRLLLNTENRFVYSSG
DVLMYLLNCPNFTIKLAVMRILAILGERFVIAREKIVAHNIFGDHNLRKKTLKLALSLSS
SVMDEDGEHFSLVDLYFDKKKVPQKWRKLRFTHYTSNDFKKSSQQKNNINETQTSIKKVT
MTTQELCEHSLQQIFDKGMALLPAESWFDFSIKASVAKAFSDDSGENIDLRNIIIETKLN
AIAFVNTIFSPPQVSSKLFELDPYAFNSLTDLISLSETKIPKELRTDALFTLECISLKHV
WCSDIIRNLGGNISHGLLFQILRYIAKTLREATDEIDEEYNVRFFYLISNLADVKPLHES
LFAAGLIPTLLEIVSIRNCPYKRTLASATHLLETFIDNSETTTEFIENDGFTMLITSVAN
EIDFTLAHPETWQPPKYSVVYYSISFRELAYIRSLLKLVLKLLSTDSGDRIRNLIDSPIL
VSLKKILENKLVFGLTLITYTLDVVQKVINSEPTIYPVLVEAGLIPYVIDNFPKLIGPSA
ELLSLLPDVVSAICLNPEGLKQVKEKGLINNLFDFLLDADHARILTGGDRSTEYGTDIDE
LARHYPDLKANIVEALCNVIRKMPSTFRNEREFLFTSPKDQKYFFHRKNEEILTDKEEHE
PAYWELLDKGTMLDTFTSVLFGMSLGNGSFSQVPQHLEARDFLAIIFMENPPYEYFTSVA
ISNVTEVLQYLDEKYEDYAFMDVMKVLNDQLENLNDFLNSPNDRSFFLERDGENSVRSCH
SKLCRLAAILNIVTNVYIDLTTLSCKRIMQIYSYFDKRGFSLIKNLKLLFQKCALEEMYI
RQHMPDSVITETMPLPIVDVSGDGPPLQIYIDDPKKGDQKGKITSVKTRNTLQMRTILYT
LQSNTAILFRCFLRLSHSRNMDLEHKDLTTEVHIFENVVENVIEMLKATELEGHLPYILV
LLNFNTFVFTIPKASPNSTEILQTIPAYIFYQKGGYLLYLHIIRDLFTRMTKIKDLSSLD
NINYIDESNGILTLSCLINALTFYNKSMQTETMENVQSIGKYYVSIDDDYNIMKALTVPI
KVMALAMILDLDKSDSLFKTQSRNVPYSVFKQLLSMLKNIFTNVNIYTKELYELHWDLIF
PPIKKISLFEQVGIPGDVAANYLTDTGDDLPADNSIGLFSPEQWEKYKKLIGEDKSIYYP
QPMQAQYYKGCSSKELDELRDTFFNDGLPSRIFTVLPFYPKLVNAFAKTLLQIFTKYDEP
TEVFAGRILDRILETDLDDPATLSSLIHLFGIFLNEKYIYQKASHLMQRFIEYLEKSLKP
EHVNTPWFSKALYVYEIILAKSELPHLEELSKDVLLRYPLLSMAKVFRIPDPMKQKLFDI
LIRVSDISNFYSALATSRILIFYSRDELYANNIARSGILSRLLKVIGSFQKLDKINFLES
SFLLLTRRCFETTENVDALIRAEINRSFTARPLGGGDDAVRELTTILEEKAHVVMRSPSQ
FIDVLCETARFHEFDDQGALVDYSLKRFLGEKDKNTQASSTEKSDIYERTGIMHLLLSQL
MAASEKDWLSEPANSSDLPENKKAQLDPSRNPVCAYMIFLLKLLVELVSSYNQCKFEFLT
FSRRNTYAERPRPRTTAINFFLYRLLDKPVGTDHDKHEAKRREVIGMLARSVIIGFLATV
QDDRTTKTDVKLADPHMNFIRKFAIEAIIKAIRNATSSSKLLESNHLKLDMWFRIITSMV
YVQAPYLRQLLDSNKVEADQYQLCKLVIDLGLPSVITEAMASIDLNYPFSKKIFNVAVEA
LNTISSTRNNFSEHFKIEDHDEVEDEVDESDKEEIPDMFKNSALGMYDVEDIEEDDDDDT
SLIGDDDAMAFVDSDNGFEVVFSDEDDDMGEEDADDARSDSEENELSSEMQSSTADGTDV
DYEVDDADGLIINIDQPSGDDEEMADYDANISHSSHSENEDDASMDVIEVYDDELSSGYD
VDLSDYDVDESDWDSGLSSLSISDEDSESSEDEPINSTRMGDSRRRWLIAEGVELTDDSQ
GESEEDDRGVFRGIEHIFSNENEPLFRVHDEMRHRNHHRSINRTHFHSAMSAPSLSLLNR
GRRNQSNLINPLGPTGLEQVENDISDQVTVAGSGSRPRSHHLHFSEVLVSGSFFDEPVLD
GIILKSTVSRWKDIFDMFYDSKTYANCIIPTVINRLYKVSLALQKDLENKREQEKLKNKN
LLFNEAKVESHNSSDAISVEQDDIQESNVTHDDHEPVYVTIQGSEVDIGGTDIDPEFMNA
LPDDIRADVFAQHVRERRAEARLNSDHNVHSREIDSDFLEAIPEDIREGILDTEAEEQRM
FGRIGSSADVIRADDDVSNNDEEVENGLDHGNSNDRNNADPEKKKPARIYFAPLIDRAGI
ASLMKSVFISKPYIQREIYHELFYRLCSSKQNRNDLMNTFLFILSEGIIDQHSLEKVYNI
ISSRAMGHAKTTTVRQLPSDCTPLTVANQTIEILQSLIDADSRLKYFLIAEHDNLIVNKA
NNKSRKEALPDKKLRWPLWHLFSLLDRKLITDESVLMDLLTRILQVCTKTLAVLSTSSNG
KENLSKKFHLPSFDEDDLMKILSIIMLDSCTTRVFQQTLNIIYNLSKLQGCMSIFTKHLV
SLAISIMSKLKSALDGLSREVGTITTGMEINSELLQKFTLPSSDQAKLLKILTTVDFLYT
HKRKEEERNVKDLQSLYDKMNGGPVWSSLSECLSQFEKSQAINTSATILLPLIESLMVVC
RRSDLSQNRNTAVKYEDAKLLDFSKTRVENLFFPFTDAHKKLLNQMIRSNPKLMSGPFAL
LVKNPKVLDFDNKRYFFNAKLKSDNQERPKLPITVRREQVFLDSYRALFFKTNDEIKNSK
LEITFKGESGVDAGGVTREWYQVLSRQMFNPDYALFLPVPSDKTTFHPNRTSGINPEHLS
FFKFIGMIIGKAIRDQCFLDCHFSREVYKNILGRPVSLKDMESLDPDYYKSLVWILENDI
TDIIEETFSVETDDYGEHKVINLIEGGKDIIVTEANKQDYVKKVVEYKLQTSVKEQMDNF
LVGFYALISKDLITIFDEQELELLISGLPDIDVDDWKNNTTYVNYTATCKEVSYFWRAVR
SFDAEERAKLLQFVTGTSKVPLNGFKELSGVNGVCKFSIHRDFGSSERLPSSHTCFNQLN
LPPYESYETLRGSLLLAINEGHEGFGLA
NT seq
9807 nt
NT seq
+upstream
nt +downstream
nt
atggtgctttttactcggtgtgaaaaggcaagaaaggagaaactcgccgctggttataag
cccttagttgattatttgattgattgtgatactcccacatttttagaaagaattgaggca
atccaagagtgggaccgatccagagatgatctttatgtttggattcccattctagacaga
atggacgggctgttgttaaaagtggcagagaaatataaatacaagcaagaccccaagaag
gagtgtgaagtcaaattggtggaaatggaagcgcatgatgttgattattgtttgaaaatg
ctaaagtttactcgtcgactacttctaaatacagaaaacaggtttgtttattcatctgga
gatgttttaatgtatctactgaattgtccgaattttacaataaaactagcggtcatgcga
attttagccattttaggggaaaggtttgtgattgcgagagaaaaaatagttgcacataac
atatttggagatcacaacctcaggaaaaaaactctcaaactagctttatctctgtcatct
tccgtcatggatgaagacggagagcacttttctcttgtcgatctatattttgataagaaa
aaagtgcctcaaaaatggagaaagttgagatttacacattatacttcaaacgactttaaa
aagtcaagccagcaaaaaaataacattaatgaaacccaaacttccattaagaaggtaact
atgacgacccaagaactgtgtgaacactcactacagcaaatatttgataagggtatggcc
cttttacccgcagaaagttggtttgatttctcaataaaagcttcggtggcgaaggccttc
agtgatgattcaggtgaaaatatagatttgagaaatataattattgaaacaaaactgaat
gctattgcatttgttaacaccattttctcgcctcctcaagtaagctcgaagttatttgaa
ttagatccgtatgcttttaatagtctaactgatttgatatcgttgtctgaaaccaaaata
ccaaaagagctaagaacggatgctttattcacattggaatgtatatccttgaagcatgtc
tggtgctcagacattatcagaaatctcggtggtaacatatcgcatggtctgttgtttcag
attctccgttacattgccaagacattgagagaagcgacagacgaaatcgatgaagaatat
aatgtgaggttcttttacttgatatcaaatttagctgacgttaagcctttgcatgaatct
cttttcgccgcgggtttaatacctactttattggaaattgtatctataagaaattgccca
tataagcgtaccctcgcatctgctacccatctcctagaaacatttatagataacagtgaa
actaccactgaatttatcgaaaatgatgggtttactatgctgatcacttcagtcgccaat
gagattgatttcacgcttgcacatccagagacgtggcaaccgccaaaatattcagtggtt
tattattcaatttcttttagggagttggcatatattagaagtttattgaaactcgttctc
aaattattaagcacagactcaggggatagaattagaaatttaatagattcgccgatactt
gtttcattaaagaaaatcctagaaaataaacttgtattcggtttaacattaataacttac
actctggatgtagttcagaaagtaataaatagtgagcctactatttatcctgttctggtt
gaagcaggacttattccatatgttatcgataattttccaaagttaattgggccttccgcc
gaattattaagtttacttccagatgtcgtttctgccatatgcttgaatccagaagggctg
aagcaagttaaagaaaagggtctcataaacaatttgtttgatttcttactcgatgctgac
cacgcgcgtatattaacaggtggagatcgttctacggaatatggtactgacattgatgaa
ttagcaagacattatccagacttaaaggcaaatatcgtggaggctttgtgtaacgtcatc
agaaaaatgccaagtacctttagaaatgaaagagagtttctttttacttcaccaaaagat
caaaagtacttttttcacagaaaaaatgaggaaatattgacagataaagaggaacatgaa
cctgcatactgggagctattagataagggaactatgctggacacatttaccagtgttttg
tttggtatgtctttaggaaatggttctttttcacaggtgccacaacatctggaagcgaga
gattttctggcaataatatttatggaaaatcctccttatgaatactttacctccgtggca
atctcaaatgttactgaggtcctccagtatctggatgaaaaatacgaagactacgcattc
atggatgttatgaaagtattgaacgatcaattggagaacctgaatgattttttgaatagt
ccaaatgatagaagtttctttttagaaagagatggggaaaactcggtgcgttcatgccat
tcaaaactttgtcgacttgccgctattttgaacattgttacgaatgtatacattgacctc
actaccttatcttgtaagagaatcatgcagatctattcttattttgacaaaagaggattt
tctttaattaaaaacttaaagttgctattccagaaatgtgcgttggaggaaatgtacata
cgccaacatatgccagattctgttattacagaaacaatgccgttgcctatagtggatgtt
tccggagatggaccaccacttcaaatttatatcgatgacccaaaaaagggtgatcaaaag
gggaaaattaccagcgtaaaaacgagaaatactcttcaaatgcgaacaatactgtataca
ttacaatcaaatactgcaattctatttcgctgctttttaaggttaagccactctaggaat
atggatctagagcataaagatttgacgacagaagttcatatatttgagaacgttgttgaa
aatgttattgaaatgttgaaggccaccgaactcgaaggtcatctaccgtatattctcgtt
ttattaaacttcaacacctttgtgtttactattccaaaggcttcccctaattccactgaa
atattacaaacaataccggcttatattttctatcaaaaggggggctatttactttatttg
cacattataagggatctctttacgagaatgacaaaaataaaagatttatcctcacttgat
aacataaactacatagatgagtccaacggtatcctaaccttaagctgtttaattaatgct
ctcaccttttacaacaaatcaatgcaaactgaaaccatggagaatgtccaaagtattggt
aagtattacgtttcaatagatgacgattataatattatgaaagctttaacagttcctatt
aaggtaatggctctcgcaatgattttagatttggataaatcggatagcctcttcaagaca
cagtcccgtaatgtgccttactcagttttcaagcaacttcttagtatgctcaaaaatata
ttcactaatgtgaacatctataccaaggaattatatgaattgcattgggacctaatattc
ccaccaattaaaaaaattagcttgtttgagcaagtcggcattcccggtgatgttgcggca
aactatttaacagatactggtgatgatcttcctgcagataacagtattggcctgttttcg
cctgaacaatgggaaaaatataaaaaattaatcggtgaagataaatccatctactatcca
caaccaatgcaagctcagtattacaaaggatgttcctcaaaagaattagatgagctgaga
gatacctttttcaatgacggtttaccatctaggatcttcactgtactccctttctatcct
aaacttgtaaacgcgtttgcaaaaactttgctacaaatttttacgaaatacgatgaaccc
actgaagtgtttgctggtagaatcttagatcgaattttagagacagatctagatgaccct
gctactttatcttccttaatccatttatttggtatattcctgaacgagaaatatatttat
caaaaggcttcgcatttaatgcaaaggttcattgaatatcttgagaagtctctgaagcca
gaacatgttaatacgccttggttttcgaaagctctttacgtttacgaaattatactggcg
aaatctgagcttccacacctcgaagagctttccaaggatgttcttctgagatatccattg
ctttccatggcgaaagtctttcgcataccagaccctatgaagcagaaattatttgacata
ctgatcagagtttctgatatttccaatttttattctgcactggcaacatcacgcatactt
attttctactctagggatgagttgtatgctaacaacatagctagatcgggaatattatct
agattgttgaaagtaattggaagtttccaaaaactagacaaaataaactttttagagtca
tctttccttttattaaccaggagatgttttgaaacgactgaaaatgttgatgctttaata
cgtgcagaaattaatagaagctttacagcaagaccgttaggtggtggggatgatgctgta
cgtgagttaaccactattctagaagaaaaggcgcatgtggtcatgcgtagtccctctcaa
tttattgacgttctttgcgaaacagctcggttccatgaatttgatgatcaaggtgcgttg
gttgattactcattgaaaagatttcttggtgaaaaagataagaatacgcaagcctcaagt
acagaaaaatcagatatctacgagagaacggggatcatgcatttattactgtcacaactt
atggctgcttctgagaaagactggttgtctgaaccggccaactcctcggatttgcctgag
aacaaaaaagcccaattggacccatcaagaaatcctgtatgtgcttacatgatttttctt
ttgaagcttttggtcgagttagttagcagttacaatcaatgtaaatttgagttcttaact
ttcagtagaagaaacacatatgcagaacgccccagaccaagaacaactgctattaacttt
ttcctttatagattattagacaaacctgtcggaactgaccacgataagcatgaagctaaa
agaagagaggttattggaatgctagcacgttccgtaattattggtttcttggctactgtt
caagatgataggacgaccaagactgacgtcaagcttgctgatcctcacatgaactttatt
agaaaatttgccattgaagcgattataaaagccattcgcaacgccacttcctcttctaaa
cttttggaaagtaatcatttaaagttagatatgtggtttagaatcattacatcgatggtt
tatgtccaggctccatatcttcgccaactacttgattcaaataaagttgaggcagatcag
taccaattgtgcaaactggttatagacctcggtcttccgtcagttatcacggaagccatg
gccagtatagacttaaactatcctttttccaaaaagattttcaacgtcgctgttgaagct
ctaaacacaattagttcgacaaggaacaatttttctgagcacttcaaaattgaagatcat
gatgaagttgaagacgaggttgacgagtctgataaggaagagatcccggatatgttcaaa
aactcagcgctgggaatgtatgacgtagaggacattgaagaagacgacgatgacgacaca
tcattaattggagacgatgatgctatggcatttgttgatagtgataacggatttgaagta
gtatttagtgacgaagatgatgatatgggagaagaagatgcagatgatgctcgttcagat
tcggaagaaaatgaattatcttctgaaatgcaatcaagtacagcggacggcacggatgtg
gactatgaggttgatgatgcagatggactaattatcaatattgaccagccctcaggagat
gatgaagaaatggcagactatgatgctaacattagccattcttctcacagtgaaaatgaa
gatgacgcttcaatggacgtcatagaagtttacgacgacgagctaagttctggatatgat
gttgatttaagcgattatgacgtagatgaatctgattgggactccgggttatccagccta
tctatttctgatgaagatagtgaaagtagcgaagatgagcctattaactccaccagaatg
ggagattcaagaaggagatggctgatagctgaaggcgtggagctaactgacgactcgcaa
ggtgagagtgaagaagatgatagaggtgttttccgtggtattgaacatatattttcaaat
gagaatgagcctttgtttagagttcatgacgaaatgcgtcatagaaaccatcatcgctca
atcaatcgtacccattttcactctgctatgagcgccccctctttaagcttattaaatcgt
ggaagaagaaaccaaagcaacctaataaatccactagggcctacaggattggaacaagtg
gagaacgatatttcagatcaggtgactgttgctggttcaggctctcgcccaagatcacat
catcttcacttttcggaagttctagtctcaggcagcttttttgatgaacctgtcttagat
ggcataattttaaagtctacggtatccagatggaaggatatattcgacatgttttacgac
tctaagacttacgctaactgtattattcctactgttatcaacagattatacaaggtcagt
ttagctttgcaaaaggacttggaaaacaaacgtgaacaagagaaattgaaaaataagaac
ctactattcaacgaggctaaagtagaaagccataacagttctgatgctatatcggtagaa
caagacgatatacaagaaagcaatgttactcatgatgaccacgagcctgtatatgttact
attcaaggttccgaggttgatataggtggtacagatattgatccagaattcatgaatgca
ttgcctgatgatataagagccgatgtctttgcacaacatgttagagaaagaagagcagaa
gctaggctaaattctgatcataacgtacactccagagaaatcgattccgattttctggaa
gcaattcctgaagacatcagagaaggaatattggatactgaggcagaggaacagagaatg
tttggtagaattggctcttcggccgatgtgattagagcagacgacgacgttagcaacaat
gacgaagaagttgaaaacggtttggatcatggaaatagtaatgatcgcaataacgccgac
cctgaaaagaaaaaaccggctagaatatactttgcaccattaattgatcgtgccgggatt
gcctcattgatgaaatctgtgtttatttcgaaaccttatattcagcgtgaaatttatcat
gagcttttctaccgtttatgttctagcaaacaaaatagaaatgatttgatgaatacattt
ttatttatactaagtgaaggtatcatagatcagcactctttggaaaaggtttataacatt
atttccagcagggcaatggggcacgcaaaaaccacgaccgttagacagttaccatcagat
tgtaccccgctaacagtggctaatcaaactatcgaaattttgcaaagtctaattgacgcg
gattctaggctaaaatacttcctgattgcagaacatgacaacctgatagtgaacaaagct
aataacaaatctaggaaagaagccttacctgacaaaaaattaagatggcctttatggcat
ttattctcacttttagatagaaagctcattacagacgaaagcgtattgatggatttgtta
acaagaatattacaagtttgtactaaaacattggctgtcctttctacaagttcaaatggt
aaagaaaatttaagcaaaaagtttcatttacctagttttgatgaggatgatctcatgaaa
attttatccatcattatgcttgatagttgtactacaagagtatttcaacaaacacttaat
ataatttacaacctctctaaattacaaggctgtatgtccattttcacgaaacatttggta
tctttagctatcagcataatgagtaaattaaagagtgctctcgatgggctatcacgtgaa
gtaggcactatcaccaccggaatggagatcaattcagagctgttacagaaatttaccctt
ccaagttctgatcaagctaaattattgaaaattttaactacggttgattttctttacact
cacaaaagaaaagaggaagagcgcaacgttaaagaccttcaatctttatatgataagatg
aacggcggaccagtgtggtcctcattgagtgagtgcttatctcaatttgaaaagagtcaa
gccatcaacacttcagccacaatcttacttccgttgatcgaatcacttatggttgtatgc
aggcgtagtgacttaagtcaaaatagaaacactgcagtcaaatatgaagatgctaaatta
ttggatttttccaaaacacgtgtcgaaaacttatttttcccatttacagacgcacacaag
aagttgttgaatcaaatgattcgttcaaatccaaaactgatgagtggtcctttcgcatta
ttggtcaagaatccaaaagttttggattttgacaacaaaagatatttcttcaatgccaaa
ttgaagtctgataatcaagagcgtcctaaattacctattaccgttcgccgtgagcaggtt
ttcttggactcttatcgagccttatttttcaagacaaacgatgaaatcaagaattctaaa
ttagagataacattcaaaggagaaagtggtgtcgatgccggtggggtaaccagagaatgg
taccaagtactatcgagacagatgttcaaccctgattatgctctttttcttcctgtacca
tcggataaaactactttccatcctaatcggacatcaggtatcaaccctgagcacctttct
ttctttaaatttatcgggatgattatagggaaagcaattagagaccaatgctttttggat
tgccattttagtcgtgaagtatacaagaatattttgggtaggcctgtatcattgaaggat
atggagtctcttgatccagattattataaatcattggtgtggattcttgaaaacgatatc
acagatattatagaggaaactttttctgttgaaactgatgattatggtgaacataaagtt
atcaatttgattgaggggggcaaggatataatagttacagaggccaataaacaggattat
gtgaaaaaggttgtcgaatataaacttcagacatctgttaaggaacaaatggataacttt
ttagtgggtttctatgcccttatatccaaagatctcattacaatatttgatgagcaggaa
ttggagttattaatcagcggtttgcctgatattgatgtcgacgactggaaaaacaatact
acttatgttaattacaccgcaacctgtaaggaagtgagttatttttggagggcagttaga
tccttcgacgctgaagaacgtgccaagttgttgcagtttgttaccggtactagtaaagtt
cctctaaatgggtttaaggaactaagcggtgtcaacggtgtttgtaaattttccatccat
cgtgattttggttcatcagaaagactaccatcatcacatacctgtttcaatcaactgaat
ttacctccttatgaatcatatgagacattgcgtggttcactattattggcaatcaatgaa
gggcatgaagggtttggtcttgcctga
DBGET
integrated database retrieval system
