Saccharomyces cerevisiae (budding yeast): YER178W
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Entry
YER178W CDS
T00005
Symbol
PDA1
Name
(RefSeq) pyruvate dehydrogenase (acetyl-transferring) subunit E1 alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00010
Glycolysis / Gluconeogenesis
sce00020
Citrate cycle (TCA cycle)
sce00620
Pyruvate metabolism
sce00785
Lipoic acid metabolism
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01200
Carbon metabolism
sce01210
2-Oxocarboxylic acid metabolism
Module
sce_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
YER178W (PDA1)
00020 Citrate cycle (TCA cycle)
YER178W (PDA1)
00620 Pyruvate metabolism
YER178W (PDA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
YER178W (PDA1)
Enzymes [BR:
sce01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
YER178W (PDA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
KRTAP7
Motif
Other DBs
NCBI-GeneID:
856925
NCBI-ProteinID:
NP_011105
SGD:
S000000980
UniProt:
P16387
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Position
V:546817..548079
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AA seq
420 aa
AA seq
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MLAASFKRQPSQLVRGLGAVLRTPTRIGHVRTMATLKTTDKKAPEDIEGSDTVQIELPES
SFESYMLEPPDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAI
AVGIENAITKLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGGSMHLYAPGF
YGGNGIVGAQVPLGAGLAFAHQYKNEDACSFTLYGDGASNQGQVFESFNMAKLWNLPVVF
CCENNKYGMGTAASRSSAMTEYFKRGQYIPGLKVNGMDILAVYQASKFAKDWCLSGKGPL
VLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGIATEAEVKAYDK
SARKYVDEQVELADAAPPPEAKLSILFEDVYVKGTETPTLRGRIPEDTWDFKKQGFASRD
NT seq
1263 nt
NT seq
+upstream
nt +downstream
nt
atgcttgctgcttcattcaaacgccaaccatcacaattggtccgcgggttaggagctgtt
cttcgcactcccaccaggataggtcatgttcgtaccatggcaactttaaaaacaactgat
aagaaggcccctgaggacatcgagggctcggacacagtgcaaattgagttgcctgaatct
tccttcgagtcgtatatgctagagcctccagacttgtcttatgagacttcgaaagccacc
ttgttacagatgtataaagatatggtcatcatcagaagaatggagatggcttgtgacgcc
ttgtacaaggccaagaaaatcagaggtttttgccatctatctgttggtcaggaggccatt
gctgtcggtatcgagaatgccatcacaaaattggattccatcatcacatcttacagatgt
cacggtttcacttttatgagaggtgcctcagtgaaagccgttctggctgaattgatgggt
agaagagccggtgtctcttatggtaagggtggttccatgcacctttacgctccaggcttc
tatggtggtaatggtatcgtgggtgcccaggttcctttaggtgcaggtttagcttttgct
caccaatacaagaacgaggacgcctgctctttcactttgtatggtgatggtgcctctaat
caaggtcaagtttttgaatctttcaacatggccaaattatggaatttgcccgtcgtgttt
tgctgtgagaacaacaagtacggtatgggtaccgccgcttcaagatcctccgcgatgact
gaatatttcaagcgtggtcaatatattccaggtttaaaagttaacggtatggatattcta
gctgtctaccaagcatccaagtttgctaaggactggtgtctatccggcaaaggtcctctc
gttctagaatatgaaacctataggtacggtggccattctatgtctgatcccggtactacc
tacagaactagagacgagattcagcatatgagatccaagaacgatccaattgctggtctt
aagatgcatttgattgatctaggtattgccactgaagctgaagtcaaagcttacgacaag
tccgctagaaaatacgttgacgaacaagttgaattagctgatgctgctcctcctccagaa
gccaaattatccatcttgtttgaagacgtctacgtgaaaggtacagaaactccaacccta
agaggtaggatccctgaagatacttgggacttcaaaaagcaaggttttgcctctagggat
taa
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