Saccharomyces cerevisiae (budding yeast): YGL173C
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Entry
YGL173C CDS
T00005
Symbol
XRN1, DST2, KEM1, RAR5, SEP1, SKI1
Name
(RefSeq) chromatin-binding exonuclease XRN1
KO
K12618
5'-3' exoribonuclease 1 [EC:3.1.13.-]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce03008
Ribosome biogenesis in eukaryotes
sce03018
RNA degradation
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09120 Genetic Information Processing
09122 Translation
03008 Ribosome biogenesis in eukaryotes
YGL173C (XRN1)
09123 Folding, sorting and degradation
03018 RNA degradation
YGL173C (XRN1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
sce03019
]
YGL173C (XRN1)
03009 Ribosome biogenesis [BR:
sce03009
]
YGL173C (XRN1)
03016 Transfer RNA biogenesis [BR:
sce03016
]
YGL173C (XRN1)
03036 Chromosome and associated proteins [BR:
sce03036
]
YGL173C (XRN1)
Messenger RNA biogenesis [BR:
sce03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
YGL173C (XRN1)
mRNA degradation factors
5'-3' decay
5' exonucleases
YGL173C (XRN1)
Ribosome biogenesis [BR:
sce03009
]
Eukaryotic type
Pre-60S particles
RNases
YGL173C (XRN1)
Transfer RNA biogenesis [BR:
sce03016
]
Eukaryotic type
tRNA degradation factors
Rapid tRNA decay (RTD) pathway factors
YGL173C (XRN1)
Chromosome and associated proteins [BR:
sce03036
]
Eukaryotic type
Gene silencing
piRNA pathway
YGL173C (XRN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
XRN_N
XRN_M
XRN1_D2_D3
XRN1_D1
SH3_12
SWIRM-assoc_2
Motif
Other DBs
NCBI-GeneID:
852702
NCBI-ProteinID:
NP_011342
SGD:
S000003141
UniProt:
P22147
Structure
PDB
PDBj
LinkDB
All DBs
Position
VII:complement(175527..180113)
Genome browser
AA seq
1528 aa
AA seq
DB search
MGIPKFFRYISERWPMILQLIEGTQIPEFDNLYLDMNSILHNCTHGNDDDVTKRLTEEEV
FAKICTYIDHLFQTIKPKKIFYMAIDGVAPRAKMNQQRARRFRTAMDAEKALKKAIENGD
EIPKGEPFDSNSITPGTEFMAKLTKNLQYFIHDKISNDSKWREVQIIFSGHEVPGEGEHK
IMNFIRHLKSQKDFNQNTRHCIYGLDADLIMLGLSTHGPHFALLREEVTFGRRNSEKKSL
EHQNFYLLHLSLLREYMELEFKEIADEMQFEYNFERILDDFILVMFVIGNDFLPNLPDLH
LNKGAFPVLLQTFKEALLHTDGYINEHGKINLKRLGVWLNYLSQFELLNFEKDDIDVEWF
NKQLENISLEGERKRQRVGKKLLVKQQKKLIGSIKPWLMEQLQEKLSPDLPDEEIPTLEL
PKDLDMKDHLEFLKEFAFDLGLFITHSKSKGSYSLKMDLDSINPDETEEEFQNRVNSIRK
TIKKYQNAIIVEDKEELETEKTIYNERFERWKHEYYHDKLKFTTDSEEKVRDLAKDYVEG
LQWVLYYYYRGCPSWSWYYPHHYAPRISDLAKGLDQDIEFDLSKPFTPFQQLMAVLPERS
KNLIPPAFRPLMYDEQSPIHDFYPAEVQLDKNGKTADWEAVVLISFVDEKRLIEAMQPYL
RKLSPEEKTRNQFGKDLIYSFNPQVDNLYKSPLGGIFSDIEHNHCVEKEYITIPLDSSEI
RYGLLPNAKLGAEMLAGFPTLLSLPFTSSLEYNETMVFQQPSKQQSMVLQITDIYKTNNV
TLEDFSKRHLNKVIYTRWPYLRESKLVSLTDGKTIYEYQESNDKKKFGFITKPAETQDKK
LFNSLKNSMLRMYAKQKAVKIGPMEAIATVFPVTGLVRDSDGGYIKTFSPTPDYYPLQLV
VESVVNEDERYKERGPIPIEEEFPLNSKVIFLGDYAYGGETTIDGYSSDRRLKITVEKKF
LDSEPTIGKERLQMDHQAVKYYPSYIVSKNMHLHPLFLSKITSKFMITDATGKHINVGIP
VKFEARHQKVLGYARRNPRGWEYSNLTLNLLKEYRQTFPDFFFRLSKVGNDIPVLEDLFP
DTSTKDAMNLLDGIKQWLKYVSSKFIAVSLESDSLTKTSIAAVEDHIMKYAANIEGHERK
QLAKVPREAVLNPRSSFALLRSQKFDLGDRVVYIQDSGKVPIFSKGTVVGYTTLSSSLSI
QVLFDHEIVAGNNFGGRLRTNRGLGLDASFLLNITNRQFIYHSKASKKALEKKKQSNNRN
NNTKTAHKTPSKQQSEEKLRKERAHDLLNFIKKDTNEKNSESVDNKSMGSQKDSKPAKKV
LLKRPAQKSSENVQVDLANFEKAPLDNPTVAGSIFNAVANQYSDGIGSNLNIPTPPHPMN
VVGGPIPGANDVADVGLPYNIPPGFMTHPNGLHPLHPHQMPYPNMNGMSIPPPAPHGFGQ
PISFPPPPPMTNVSDQGSRIVVNEKESQDLKKFINGKQHSNGSTIGGETKNSRKGEIKPS
SGTNSTECQSPKSQSNAADRDNKKDEST
NT seq
4587 nt
NT seq
+upstream
nt +downstream
nt
atgggtattccaaaatttttcaggtacatctcagaaagatggcccatgattttacagctt
attgagggaacacagattcctgagtttgataacttatacctggatatgaattcgatttta
cataattgtacgcatggtaacgacgatgatgtaaccaagcgattaactgaagaagaggtt
tttgcaaaaatctgtacgtatatcgatcacctttttcaaacaatcaagcccaagaagatt
ttctacatggctattgatggtgtggcccctcgtgccaagatgaatcaacaaagagctcgt
agattcagaaccgctatggatgcagaaaaagccttgaagaaggctattgagaatggtgac
gagattcctaagggtgagccatttgattcgaattctattactccaggtacggagtttatg
gccaaattgaccaaaaacttacaatattttattcacgacaagatttctaacgattccaaa
tggagggaagtgcaaatcatattttctggccatgaagttccaggtgaaggtgaacacaag
atcatgaactttataaggcatttaaaatcccaaaaggatttcaaccagaatacgagacat
tgtatttacggtcttgacgcagatttgattatgctgggtttgtctactcatgggccacat
tttgcgttattgagagaagaagtgacatttggtagaagaaatagtgaaaaaaaatcgctt
gaacatcaaaatttctacttattacatctttctttattaagagaatacatggagttggaa
ttcaaagaaattgccgatgaaatgcaatttgaatacaattttgaacgtattttggatgat
tttattcttgtcatgttcgtcattggtaatgatttcttgcccaatttgccagatttgcac
cttaacaaaggagcatttcccgttttgttacaaacgttcaaagaagctcttttacatact
gatggctacattaatgaacatggtaaaataaatttaaagagattaggtgtctggttaaat
tatctgtctcaatttgagttattaaatttcgaaaaggatgatatagacgttgagtggttc
aacaagcaattagagaatatttctttggagggtgaaaggaaaagacagagggttggtaaa
aaattactggtaaaacaacagaagaaattaattggaagtataaaaccatggttgatggag
caattacaggaaaaattatcgcctgatttaccagatgaagaaattccaactttagagtta
cctaaggacttagacatgaaagatcatttagaatttttaaaagaattcgcttttgatttg
ggtctttttataacgcattccaaatccaaaggtagttattcgctaaaaatggatcttgat
tctattaatcctgatgaaacagaagaagaatttcaaaatcgtgttaattctatcaggaaa
acaataaaaaaatatcaaaatgctatcatcgtggaggacaaagaagaattggaaactgaa
aaaacgatttataatgaaaggtttgaacgttggaagcatgagtattatcacgacaagtta
aaatttacgacagacagtgaagaaaaagtgagagatcttgctaaagactacgttgaaggt
ttacaatgggttctatattattattatagaggatgtccatcttggtcgtggtactatccg
caccattatgcaccaagaatctccgacttagccaagggtttagatcaagacattgaattt
gatttgagcaaaccatttactccattccagcaactaatggcagttttaccggaaaggtcc
aaaaatctgatacctcccgcctttaggccattaatgtacgatgaacagtcgccaatccac
gatttctatcccgctgaggttcaacttgataaaaacggcaagacagctgattgggaagct
gtggttttgatatcgtttgtagatgaaaaaaggttgattgaggctatgcaaccttatttg
cgcaagttatcacctgaagaaaaaacgagaaatcaatttggcaaggacttgatatattcc
tttaatcctcaagttgataacctttataagagtccgttgggcggcattttttctgatatt
gaacacaatcattgtgtcgaaaaagagtacatcaccatcccattggacagctccgagatt
cggtatggtttattacctaatgctaaactcggtgccgaaatgctggcgggtttccccacg
ttattgtctttaccatttactagttcactggagtacaatgagacaatggttttccaacaa
ccttctaaacaacaatcaatggtcttacaaataactgacatatacaaaacgaataatgtt
actttggaggacttttccaagaggcatttaaacaaagtgatttatacaagatggccatat
ttaagagaatccaaattggtctctttaacggatggtaagactatctatgaatatcaggag
tccaatgataagaaaaagttcggattcataacgaagcctgcggaaacccaggacaaaaaa
cttttcaatagtttgaagaattcaatgctaaggatgtatgctaaacagaaagctgttaaa
ataggacctatggaagccattgctaccgtctttccagtgactggtttggtgagagactct
gatggtggttatattaagacctttagccctaccccagattactatccattgcaactggtt
gttgaatctgttgtcaacgaggatgaaagatataaagaaagaggacccattcctattgaa
gaggaatttccattgaattcaaaagttattttcttaggtgattatgcctatggtggtgaa
actactattgacggttacagcagtgaccgcagactaaaaattactgtagaaaagaagttt
ttggatagtgagcccaccatcggcaaagaaaggttacaaatggatcatcaagccgttaaa
tattatccgtcttatattgtgtccaagaacatgcacttacaccccttgtttttgtctaag
attacttccaagttcatgattactgacgctactgggaagcatatcaatgttggtatcccg
gttaagttcgaagctagacaccaaaaggttttaggttacgcgaggaggaaccctaggggc
tgggaatactcaaatttaactctaaatttactgaaagagtatagacaaactttcccagat
ttttttttcaggttgtccaaggtaggtaatgatatcccagttttggaagatcttttcccc
gatacttccactaaggatgccatgaatttattagatggtatcaaacaatggctaaagtat
gtctcatcgaagtttatcgcggtatctttggagtctgactccttaactaagacatcgatt
gctgccgtggaagatcatatcatgaaatacgcagctaacatcgaaggtcatgaaagaaaa
cagttagccaaagttcctcgtgaggctgttttgaatccaagatcatcatttgcactctta
cgtagtcaaaagttcgatttgggtgaccgtgttgtttatatccaagattctggtaaggta
ccaattttctcaaagggtacagttgttggctatactactctcagttcatcattatcaatt
caggtcttatttgatcatgaaatcgtggccggtaataattttggcggcaggttgcgcacg
aatagaggcttagggcttgatgcctctttcttattgaatattactaacaggcagttcatt
tatcactccaaggcttccaaaaaggctttggaaaagaaaaagcaatctaacaataggaac
aataataccaaaactgctcacaagactccttcaaagcaacaatctgaagaaaaactgaga
aaagaaagggcacatgatttattgaattttatcaaaaaggataccaatgaaaagaattct
gaaagtgtagacaacaagagcatgggatcgcaaaaagattccaaacccgcaaagaaagtt
ttgttaaaaagaccagctcagaaaagcagtgaaaacgtgcaagttgatttggccaatttt
gaaaaagcaccgcttgataatccaactgttgctggatctattttcaatgccgttgcaaat
caatattctgatggtataggcagtaatttgaatatcccaactccacctcacccaatgaat
gtggttgggggtcctattcctggagcgaatgatgttgcagatgttggtttgccgtacaat
attcccccaggttttatgacgcatcctaatggtcttcacccattacaccctcaccagatg
ccttaccctaatatgaatggaatgtctattccgccaccagcaccacatgggtttggacaa
ccgatttccttcccacctccacctcctatgacaaatgtttcagatcaaggaagtcgtatt
gttgtcaatgaaaaggaaagccaagatttgaaaaaattcattaatggtaaacagcacagc
aatggttcaactattgggggagaaacaaagaacagtaggaaaggcgagattaaaccttct
tctggcacaaactctactgaatgtcaatcgccaaagtcacaaagcaatgctgctgaccgt
gataataaaaaagacgaatctacttag
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integrated database retrieval system
