Saccharomyces cerevisiae (budding yeast): YGR061C
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Entry
YGR061C CDS
T00005
Symbol
ADE6
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00230
Purine metabolism
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
Module
sce_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
YGR061C (ADE6)
Enzymes [BR:
sce01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
YGR061C (ADE6)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-GeneID:
852952
NCBI-ProteinID:
NP_011575
SGD:
S000003293
UniProt:
P38972
LinkDB
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Position
VII:complement(611889..615965)
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AA seq
1358 aa
AA seq
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MTDYILPGPKALSQFRVDNLIKDINSYTNSTSVINELRSCYIHYVNGIAQNLSEQDTKLL
EVLLTYDSALDIANDPLARQLNDAVANNLPSSALGEDTYLIRVVPRSGTISPWSSKATNI
AHVCGLQDKVQRIERGLALLIKTVPGFPLLENLNDISLKCVYDRMTQQLYLTEPPNTMSI
FTHEEPKPLVHVPLTPKDTKQSPKDILSKANTELGLALDSGEMEYLIHAFVETMKRDPTD
VELFMFAQVNSEHCRHKIFNADWTIDGIKQQFTLFQMIRNTHKLNPEYTISAYSDNAAVL
DSENDAFFFAPNSTTKEWTSTKERIPLLIKVETHNHPTAVSPFPGAATGSGGEIRDEGAT
GRGSKTKCGLSGFSVSDLLIPGNEQPWELNIGKPYHIASALDIMIEAPLGSAAFNNEFGR
PCINGYFRTLTTKVLNHQGKEEIRGFHKPIMIAGGFGTVRPQFALKNTPITPGSCLIVLG
GQSMLIGLGGGAASSVASGEGSADLDFASVQRGNPEMERRCQQVIDACVALGNNNPIQSI
HDVGAGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSPQDL
SIFEEICKRERAPFAVVGHATAEQKLIVEDPLLKTTPIDLEMPILFGKPPKMSRETITEA
LNLPEANLSEIPSLQDAIQRVLNLPSVGSKSFLITIGDRSVTGLIDRDQFVGPWQVPVAD
VGVTGTSLGETIISTGEAMAMGEKPVNALISASASAKLSVAESLLNIFAADVKSLNHIKL
SANWMSPASHQGEGSKLYEAVQALGLDLCPALGVAIPVGKDSMSMKMKWDDKEVTAPLSL
NITAFAPVFNTSKTWTPLLNRNTDDSVLVLVDLSAKQETKSLGASALLQVYNQVGNKSPT
VYDNAILKGFLESLIQLHQQKEDIVLAYHDRSDGGLLITLLEMAFASRCGLEINIDGGDL
ESQLTNLFNEELGAVFQISAKNLSKFEKILNENGVAKEYISIVGKPSFQSQEIKIINSTT
NDVIYANSRSELEQTWSKTSYEMQKLRDNPKTAEEEFASITDDRDPGLQYALTYNPADDM
KIGLELSSQRPKVAILREQGVNGQMEMAWCFQQAGFNSVDVTMTDLLEGRFHLDDFIGLA
ACGGFSYGDVLGAGAGWAKSVLYHEGVRSQFSKFFNERQDTFAFGACNGCQFLSRLKDII
PGCENWPSFERNVSEQYEARVCMVQISQEKDNSSEESVFLNGMAGSKLPIAVAHGEGKAT
FSKSAEQLEKFEKDGLCCIRYVDNYGNVTERFPFNPNGSTNGIAGIKSPNGRVLAMMPHP
ERVCRLEANSWYPEGKYEEWGGYGPWIRLFRSARRWVG
NT seq
4077 nt
NT seq
+upstream
nt +downstream
nt
atgactgattatattttgccgggtcccaaggccttatctcagttcagagtcgataatcta
attaaagatataaactcctatacaaacagtacttctgtcatcaatgaattgcgttcgtgt
tacattcactatgtcaacggcatcgctcaaaatttgtctgaacaggacactaaattgcta
gaagttttgttgacttacgattctgctttagatattgctaacgatccattagcaagacaa
ttaaacgatgctgtcgctaataatttacccagttcagctcttggcgaagacacatatttg
attagagttgttcctagatcaggcactatctctccttggtcttccaaggctactaatatt
gctcatgtatgcgggctacaagacaaagttcaacgtattgaaagaggtttagccttactc
ataaagactgttccaggtttccctcttttggaaaatctaaatgatatttcattgaagtgt
gtctacgataggatgacacaacaattatatctgaccgaaccaccaaatacgatgagtatt
ttcacacatgaagagccaaagccattagttcacgttcctttaactcctaaggacactaaa
cagtctccaaaggatattttatccaaagctaatacggaattgggtttagctctagatagt
ggagaaatggaatatttgattcatgcattcgtcgaaactatgaaaagagatcctactgat
gttgagttatttatgttcgctcaagttaattctgaacattgtcgtcacaagatcttcaat
gctgattggaccattgatggaataaaacaacaattcaccttgtttcaaatgattagaaat
acccataaattaaacccagaatatactattagcgcctattctgataatgcagccgttttg
gatagtgaaaatgatgcctttttctttgcaccaaattcaactacaaaggaatggacctct
acaaaggaaagaattccattacttatcaaagtcgaaactcacaaccatccaacagccgtg
tctcctttcccaggtgctgctacaggttctggtggtgaaatcagagacgagggtgctaca
ggcagaggttccaagactaagtgtggtttgagtggattctctgtcagcgaccttttgata
ccaggtaatgaacaaccttgggagttgaatattggtaagccttaccatattgcatctgca
ttagatattatgattgaggctcctttgggttcagctgcatttaacaatgagtttggtaga
ccttgtataaacggttacttcagaactttaactacaaaggttttgaatcaccaagggaag
gaggaaatcagagggttccacaagccaattatgattgcgggtggtttcggtactgttaga
cctcaatttgctttgaagaacaccccaataactccaggctcttgtttaattgtacttggt
ggtcaatctatgctgattggtttaggtggtggtgctgcttcttctgtagcttccggtgaa
ggttccgccgatttggattttgcttctgtacaaagagggaaccccgaaatggaacgtcgt
tgccaacaagtgattgacgcttgtgttgccttaggtaacaataatcctatccaatctatt
cacgatgttggtgctggtgggttatccaacgctttgccagaattggttcatgacaatgac
ttgggtgctaaattcgatattagaaaggtcctctccttagaacctggtatgtcaccaatg
gaaatttggtgtaatgaatcacaagaacgttatgttcttggtgtttctcctcaagactta
tccattttcgaggaaatctgtaagagagaaagagcaccatttgctgtcgtcggtcacgca
accgctgaacaaaaattgattgtagaagatcctcttttgaaaacaactccaattgattta
gaaatgccaattttatttggtaagcctccaaagatgtcaagagaaaccataactgaagca
ctaaatctaccagaggcaaatttgagcgaaattccttccctacaagatgctattcaaaga
gttctaaacttaccatctgttggctcaaagtcatttttgattactattggtgacagatcc
gtcacaggtctaattgatagggatcaatttgttggtccttggcaagtacctgttgcggat
gtcggtgttaccggtacctctttgggtgagacaataatttccacaggtgaagccatggct
atgggtgaaaaaccagttaacgccctaatctccgcatctgcttccgctaaattatctgtg
gcagaatctttattgaacatattcgctgctgatgtgaaatctttaaatcatatcaagcta
tctgctaactggatgtctccagcctctcatcaaggtgagggttctaagttatatgaagcc
gttcaagcattaggtctggatttatgtcctgcattaggtgttgctatccctgttggtaag
gattccatgtccatgaagatgaaatgggatgataaggaagttactgcaccattgtcattg
aatatcacagcatttgcaccagttttcaacactagtaaaacgtggactccattgctaaat
agaaacacagatgattctgtccttgtcttggttgatctatcagctaaacaagagactaag
tcactaggtgcctctgctttgttgcaagtttacaaccaagttggtaacaagtcgcctact
gtgtatgataacgccattttgaagggtttcttggaaagtttaatccaattgcatcaacaa
aaggaggatatagtgcttgcctaccatgataggtctgatggtggtctactaatcacttta
ctggaaatggcatttgcttccagatgcggcttagaaatcaacattgacggtggagaccta
gaaagtcaattaacaaacctattcaatgaagaattaggtgcagtattccagatttctgct
aagaacttgagcaagttcgaaaaaatcttgaacgagaacggagttgctaaagaatatatt
tctattgttggtaagccatccttccaaagccaggaaatcaagattattaactccacaaca
aatgatgtaatttacgccaattcgagatctgaattggagcaaacttggagtaagacatct
tacgaaatgcagaaattgagagacaatccaaaaacagccgaagaagagtttgccagtatc
acggacgatagagatcccggtttgcagtatgccctaacatacaacccagccgatgatatg
aagatcggattagaattatccagtcaaaggccaaaggttgctatcttaagagagcaaggt
gtgaacggtcaaatggaaatggcatggtgcttccaacaagctggattcaactcagtggat
gtcactatgacagatttgctagaaggtaggttccatttggatgacttcatcggtcttgcc
gcatgtggtggtttctcttatggtgatgtcttaggtgcaggtgcgggttgggctaaatcc
gtattgtatcacgaaggtgtgcgctcgcaattttctaagttcttcaatgaaagacaagat
acatttgcttttggtgcttgtaatggttgtcaattcttgagtagattaaaagatatcata
cccgggtgtgaaaactggccaagtttcgaaagaaatgttagtgaacaatatgaagcccgt
gtatgtatggtgcaaatatctcaagaaaaggacaattctagcgaggaatctgttttcttg
aatggcatggcaggatccaaattgccaattgctgtcgcacatggtgaaggtaaagcaaca
ttttctaaaagcgctgaacaactggaaaagttcgaaaaggatggtttatgttgtataagg
tatgtggacaactacggtaacgtcaccgaaaggttccccttcaaccccaatgggtcgacc
aatggtattgccggtatcaagtcaccaaatggtagagtgcttgccatgatgccacatcct
gaaagagtttgcagattggaggccaattcctggtatccagagggcaaatacgaagagtgg
ggtggatacggtccatggattagattattcagatctgccagaagatgggtcggttga
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