Saccharomyces cerevisiae (budding yeast): YHR079C
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Entry
YHR079C CDS
T00005
Symbol
IRE1, ERN1
Name
(RefSeq) bifunctional endoribonuclease/protein kinase IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce04141
Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
YHR079C (IRE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
sce01001
]
YHR079C (IRE1)
Enzymes [BR:
sce01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
YHR079C (IRE1)
Protein kinases [BR:
sce01001
]
Serine/threonine kinases: Other
IRE family
YHR079C (IRE1)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ
Kdo
Sporozoite_P67
PQQ_2
Motif
Other DBs
NCBI-GeneID:
856478
NCBI-ProteinID:
NP_011946
SGD:
S000001121
UniProt:
P32361
Structure
PDB
PDBj
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All DBs
Position
VIII:complement(258244..261591)
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AA seq
1115 aa
AA seq
DB search
MRLLRRNMLVLTLLVCVFSSIISCSIPLSSRTSRRQIVEDEVASTKKLNFNYGVDKNINS
PIPAPRTTEGLPNMKLSSYPTPNLLNTADNRRANKKGRRAANSISVPYLENRSLNELSLS
DILIAADVEGGLHAVDRRNGHIIWSIEPENFQPLIEIQEPSRLETYETLIIEPFGDGNIY
YFNAHQGLQKLPLSIRQLVSTSPLHLKTNIVVNDSGKIVEDEKVYTGSMRTIMYTINMLN
GEIISAFGPGSKNGYFGSQSVDCSPEEKIKLQECENMIVIGKTIFELGIHSYDGASYNVT
YSTWQQNVLDVPLALQNTFSKDGMCIAPFRDKSLLASDLDFRIARWVSPTFPGIIVGLFD
VFNDLRTNENILVPHPFNPGDHESISSNKVYLDQTSNLSWFALSSQNFPSLVESAPISRY
ASSDRWRVSSIFEDETLFKNAIMGVHQIYNNEYDHLYENYEKTNSLDTTHKYPPLMIDSS
VDTTDLHQNNEMNSLKEYMSPEDLEAYRKKIHEQISRELDEKNQNSLLLKFGSLVYRIIE
TGVFLLLFLIFCAILQRFKILPPLYVLLSKIGFMPEKEIPIVESKSLNCPSSSENVTKPF
DMKSGKQVVFEGAVNDGSLKSEKDNDDADEDDEKSLDLTTEKKKRKRGSRGGKKGRKSRI
ANIPNFEQSLKNLVVSEKILGYGSSGTVVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLT
ESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQ
IASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQS
SFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRS
IDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRSLIAEATDLISQM
IDHDPLKRPTAMKVLRHPLFWPKSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVI
PSGDWTVKFDKTFMDNLERYRKYHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGF
YDYFTKRFPNLLIGVYMIVKENLSDDQILREFLYS
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atgcgtctacttcgaagaaacatgttagtattgacactgctcgtttgtgtgttttcatcc
atcatttcatgctcaatcccattgtcgtctcgcacctcaaggcggcagatagtggaagat
gaagttgcctccactaaaaagctcaatttcaactatggtgtggataaaaatataaactcg
cccattcctgctccaagaaccactgaaggtttaccaaatatgaaactcagctcatatcca
actcctaacttattgaatactgctgataatcgacgtgctaacaaaaaaggacgtagggct
gccaattctataagtgtaccctatttggagaatcgttccttgaacgaactgagtttatca
gatatactaatcgcagccgacgttgagggtggacttcatgctgtagatagaagaaatggt
catatcatatggtcaatcgaaccagaaaattttcaacctctgatagaaatacaagaacct
tcgaggttagaaacatatgaaacgttgattatagaacctttcggtgatgggaacatttac
tactttaacgcccatcaagggttacaaaaactgcctttatccatacgacaacttgtatca
acttccccgctgcacttgaaaacaaatattgtggttaatgactctggaaaaattgttgaa
gatgaaaaggtctacactggatcgatgagaactataatgtatactataaacatgttgaat
ggtgaaattatatcagcgttcggacctggttcaaaaaacgggtatttcgggagccagagt
gtggattgctcacctgaggagaagataaaacttcaggaatgtgaaaatatgattgtaata
ggcaaaactatttttgagctgggaattcactcttatgatggagcaagctacaatgtcact
tactctacatggcagcaaaatgttttagatgttcccctagcgcttcagaatacattttca
aaggacggcatgtgcatagcgcctttccgtgataaatcattgctagcaagcgatttagat
tttagaattgctagatgggtttctccgacattccccggaattattgttgggcttttcgat
gtgtttaatgatctccgcaccaatgaaaatatactggtaccgcatccctttaatcctggt
gatcatgaaagtatatcgagtaacaaagtttacttggatcagacttcgaacctctcctgg
tttgcattatctagtcagaattttccatctttagtcgaatcagctcccatatcaagatac
gcttccagtgaccgttggagggtgtcttcaatttttgaagatgagactttattcaagaac
gcaatcatgggtgttcatcagatatataataatgaatatgatcacctttatgaaaactat
gaaaaaacgaatagtttggacactacgcacaaatatccacctctgatgattgattcgtcc
gttgatacaaccgatttacatcagaataacgagatgaattcactaaaggaatacatgtca
ccagaagaccttgaggcatatagaaaaaagatacacgagcaaatatcgagagaattagat
gaaaagaaccaaaattctttgctactgaagtttggaagtctagtatatcgaattatagag
actggagtatttctgttgttatttctcattttttgtgcaatactacaaagattcaaaatt
ttgccgccactatatgtattattatccaaaattggatttatgcctgaaaaggaaatcccc
atagttgagtcgaaatcgctaaattgtccctcttcatcggaaaatgtaaccaagccattc
gatatgaaatcagggaagcaagttgtttttgaaggtgctgtgaacgatggaagtctaaaa
tctgaaaaagataacgatgatgctgatgaagatgatgaaaaatcactagatttaaccaca
gaaaagaagaagaggaaaagaggttcgagaggaggcaaaaagggccgaaaatcacgcatt
gcaaatataccaaactttgagcaatctttaaaaaatttggtagtatccgaaaaaatttta
ggttacggttcatcaggaacagtagtttttcagggaagttttcaaggaagacctgttgcg
gtaaagagaatgttaattgatttttgtgacatagctttaatggaaataaaacttttgact
gaaagcgatgatcaccctaacgtcatacgatactactgttcagaaacaacagacagattt
ttgtatattgctttagagctctgcaatttgaaccttcaagatttggtggagtctaagaat
gtatcagatgaaaacctgaaattacagaaagagtataatccaatttcgttattgagacaa
atagcgtccggggtagcacatttacattctttaaagattatccatcgagatttaaagcct
caaaatattctcgtttctacttcgagtaggtttactgccgatcagcaaacaggagcagaa
aatcttcgaattttgatatcagactttggtctttgcaaaaaactagactctggtcagtct
tcatttagaacaaatttgaataacccttctggcacaagtggttggagggccccagagctg
cttgaagaatcaaacaatttgcagtgccaagtcgaaacggaacactcttctagtaggcat
acagtagtttcatctgattctttttatgatccgttcaccaagaggaggctaacaagatct
attgatattttttctatgggatgtgtattctattatatcctatccaaagggaagcatcca
tttggagataaatattcacgtgaaagcaatatcataagaggaatattcagtcttgatgaa
atgaaatgtctacatgatagatccttaattgcagaagctacagatctgatctcccaaatg
attgatcacgatccgttaaaaagacctactgctatgaaagttctaaggcatccgttgttt
tggccaaagtcgaaaaaattggagttccttttaaaagttagtgataggcttgaaattgaa
aacagagaccctccaagtgccctgttaatgaaatttgacgccggttctgactttgtaata
cccagtggagattggactgtcaagtttgataaaacattcatggacaaccttgaaaggtac
agaaaataccattcatcaaagttaatggatctattaagagcacttaggaataaatatcat
cattttatggatttacctgaagatatagcagaactaatggggccggtacccgatggattt
tacgattacttcaccaagcgttttccaaacctattaataggtgtttatatgattgtcaag
gaaaatttaagtgacgatcaaattttacgtgaatttttgtattcataa
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