Saccharomyces cerevisiae (budding yeast): YHR183W
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Entry
YHR183W CDS
T00005
Symbol
GND1
Name
(RefSeq) phosphogluconate dehydrogenase (decarboxylating) GND1
KO
K00033
6-phosphogluconate dehydrogenase [EC:
1.1.1.44
1.1.1.343
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00030
Pentose phosphate pathway
sce00480
Glutathione metabolism
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01200
Carbon metabolism
Module
sce_M00004
Pentose phosphate pathway (Pentose phosphate cycle)
sce_M00006
Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00030 Pentose phosphate pathway
YHR183W (GND1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
YHR183W (GND1)
Enzymes [BR:
sce01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
YHR183W (GND1)
1.1.1.343 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)
YHR183W (GND1)
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Gene cluster
GFIT
Motif
Pfam:
6PGD
NAD_binding_2
F420_oxidored
NAD_binding_11
Motif
Other DBs
NCBI-GeneID:
856589
NCBI-ProteinID:
NP_012053
SGD:
S000001226
UniProt:
P38720
Structure
PDB
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Position
VIII:470960..472429
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AA seq
489 aa
AA seq
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MSADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDF
ISKLKRPRKVMLLVKAGAPVDALINQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGI
LFVGSGVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSISAKSDGEPCCEWVGPAGAGHY
VKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEITRDILKF
DDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSALKNERIRASK
VLPGPEVPKDAVKDREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLNNPAIALM
WRGGCIIRSVFLGQITKAYREEPDLENLLFNKFFADAVTKAQSGWRKSIALATTYGIPTP
AFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPECASDNLPVDKDIHINWTGHGG
NVSSSTYQA
NT seq
1470 nt
NT seq
+upstream
nt +downstream
nt
atgtctgctgatttcggtttgattggtttggccgtcatgggtcaaaatttgatcttgaac
gctgctgaccacggtttcactgtttgtgcttacaacagaactcaatccaaggtcgaccat
ttcttggccaatgaagctaagggcaaatctatcatcggtgctacttccattgaagatttc
atctccaaattgaagagacctagaaaggtcatgcttttggttaaagctggtgctccagtt
gacgctttgatcaaccaaatcgtcccacttttggaaaagggtgatattatcatcgatggt
ggtaactctcacttcccagattctaatagacgttacgaagaattgaagaagaagggtatt
cttttcgttggttctggtgtctccggtggtgaggaaggtgcccgttacggtccatctttg
atgccaggtggttctgaagaagcttggccacatattaagaacatcttccaatccatctct
gctaaatccgacggtgaaccatgttgcgaatgggttggcccagccggtgctggtcactac
gtcaagatggttcacaacggtattgaatacggtgatatgcaattgatttgtgaagcttat
gacatcatgaagagattgggtgggtttaccgataaggaaatcagtgacgtttttgccaaa
tggaacaatggtgtcttggattccttcttggtcgaaattaccagagatattttgaaattc
gacgacgtcgacggtaagccattagttgaaaaaatcatggatactgctggtcaaaagggt
actggtaagtggactgccatcaacgccttggatttgggtatgccagttactttgattggt
gaagctgtctttgcccgttgtctatctgctttgaagaacgagagaattagagcctccaag
gtcttaccaggcccagaagttccaaaagacgccgtcaaggacagagaacaatttgtcgat
gatttggaacaagctttgtatgcttccaagattatttcttacgctcaaggtttcatgttg
atccgtgaagctgctgctacttatggctggaaactaaacaaccctgccatcgctttgatg
tggagaggtggttgtatcattagatctgttttcttgggtcaaatcacaaaggcctacaga
gaagaaccagatttggaaaacttgttgttcaacaagttcttcgctgatgccgtcaccaag
gctcaatctggttggagaaagtcaattgcgttggctaccacctacggtatcccaacacca
gccttttccaccgctttgtctttctacgatgggtacagatctgaaagattgccagccaac
ttactacaagctcaacgtgactactttggtgctcacactttcagagtgttgccagaatgt
gcttctgacaacttgccagtagacaaggatatccatatcaactggactggccacggtggt
aatgtttcttcctctacataccaagcttaa
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