Saccharomyces cerevisiae (budding yeast): YHR190W
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Entry
YHR190W CDS
T00005
Symbol
ERG9
Name
(RefSeq) bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase
KO
K00801
farnesyl-diphosphate farnesyltransferase [EC:
2.5.1.21
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00100
Steroid biosynthesis
sce00909
Sesquiterpenoid and triterpenoid biosynthesis
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
Module
sce_M00102
Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
YHR190W (ERG9)
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
YHR190W (ERG9)
09180 Brite Hierarchies
09181 Protein families: metabolism
01006 Prenyltransferases [BR:
sce01006
]
YHR190W (ERG9)
Enzymes [BR:
sce01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.21 squalene synthase
YHR190W (ERG9)
Prenyltransferases [BR:
sce01006
]
Terpene biosynthesis
Squalene/phytoene synthase
YHR190W (ERG9)
BRITE hierarchy
SSDB
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Gene cluster
GFIT
Motif
Pfam:
SQS_PSY
GST_C_8
Motif
Other DBs
NCBI-GeneID:
856597
NCBI-ProteinID:
NP_012060
SGD:
S000001233
UniProt:
P29704
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All DBs
Position
VIII:484845..486179
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AA seq
444 aa
AA seq
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MGKLLQLALHPVEMKAALKLKFCRTPLFSIYDQSTSPYLLHCFELLNLTSRSFAAVIREL
HPELRNCVTLFYLILRALDTIEDDMSIEHDLKIDLLRHFHEKLLLTKWSFDGNAPDVKDR
AVLTDFESILIEFHKLKPEYQEVIKEITEKMGNGMADYILDENYNLNGLQTVHDYDVYCH
YVAGLVGDGLTRLIVIAKFANESLYSNEQLYESMGLFLQKTNIIRDYNEDLVDGRSFWPK
EIWSQYAPQLKDFMKPENEQLGLDCINHLVLNALSHVIDVLTYLAGIHEQSTFQFCAIPQ
VMAIATLALVFNNREVLHGNVKIRKGTTCYLILKSRTLRGCVEIFDYYLRDIKSKLAVQD
PNFLKLNIQISKIEQFMEEMYQDKLPPNVKPNETPIFLKVKERSRYDDELVPTQQEEEYK
FNMVLSIILSVLLGFYYIYTLHRA
NT seq
1335 nt
NT seq
+upstream
nt +downstream
nt
atgggaaagctattacaattggcattgcatccggtcgagatgaaggcagctttgaagctg
aagttttgcagaacaccgctattctccatctatgatcagtccacgtctccatatctcttg
cactgtttcgaactgttgaacttgacctccagatcgtttgctgctgtgatcagagagctg
catccagaattgagaaactgtgttactctcttttatttgattttaagggctttggatacc
atcgaagacgatatgtccatcgaacacgatttgaaaattgacttgttgcgtcacttccac
gagaaattgttgttaactaaatggagtttcgacggaaatgcccccgatgtgaaggacaga
gccgttttgacagatttcgaatcgattcttattgaattccacaaattgaaaccagaatat
caagaagtcatcaaggagatcaccgagaaaatgggtaatggtatggccgactacatctta
gatgaaaattacaacttgaatgggttgcaaaccgtccacgactacgacgtgtactgtcac
tacgtagctggtttggtcggtgatggtttgacccgtttgattgtcattgccaagtttgcc
aacgaatctttgtattctaatgagcaattgtatgaaagcatgggtcttttcctacaaaaa
accaacatcatcagagattacaatgaagatttggtcgatggtagatccttctggcccaag
gaaatctggtcacaatacgctcctcagttgaaggacttcatgaaacctgaaaacgaacaa
ctggggttggactgtataaaccacctcgtcttaaacgcattgagtcatgttatcgatgtg
ttgacttatttggccggtatccacgagcaatccactttccaattttgtgccattccccaa
gttatggccattgcaaccttggctttggtattcaacaaccgtgaagtgctacatggcaat
gtaaagattcgtaagggtactacctgctatttaattttgaaatcaaggactttgcgtggc
tgtgtcgagatttttgactattacttacgtgatatcaaatctaaattggctgtgcaagat
ccaaatttcttaaaattgaacattcaaatctccaagatcgaacagtttatggaagaaatg
taccaggataaattacctcctaacgtgaagccaaatgaaactccaattttcttgaaagtt
aaagaaagatccagatacgatgatgaattggttccaacccaacaagaagaagagtacaag
ttcaatatggttttatctatcatcttgtccgttcttcttgggttttattatatatacact
ttacacagagcgtga
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