Saccharomyces cerevisiae (budding yeast): YJL034W
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Entry
YJL034W CDS
T00005
Symbol
KAR2, GRP78
Name
(RefSeq) Hsp70 family ATPase KAR2
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
5.6.1.10
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce03060
Protein export
sce04141
Protein processing in endoplasmic reticulum
sce04156
Integrated stress response (ISR) signaling pathway
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
YJL034W (KAR2)
04141 Protein processing in endoplasmic reticulum
YJL034W (KAR2)
09140 Cellular Processes
09143 Cell growth and death
04156 Integrated stress response (ISR) signaling pathway
YJL034W (KAR2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
sce03110
]
YJL034W (KAR2)
04131 Membrane trafficking [BR:
sce04131
]
YJL034W (KAR2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sce04147
]
YJL034W (KAR2)
Enzymes [BR:
sce01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.10 non-chaperonin molecular chaperone ATPase
YJL034W (KAR2)
Chaperones and folding catalysts [BR:
sce03110
]
Heat shock proteins
HSP70 / DNAK
YJL034W (KAR2)
Membrane trafficking [BR:
sce04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
YJL034W (KAR2)
Autophagy
ER-phagy
ER stress-related proteins
YJL034W (KAR2)
Exosome [BR:
sce04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
YJL034W (KAR2)
Exosomal proteins of other body fluids (saliva and urine)
YJL034W (KAR2)
Exosomal proteins of colorectal cancer cells
YJL034W (KAR2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
BcrAD_BadFG
SPP1_GP23-1
FGGY_C
Radial_spoke_3
Motif
Other DBs
NCBI-GeneID:
853418
NCBI-ProteinID:
NP_012500
SGD:
S000003571
UniProt:
P16474
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:381327..383375
Genome browser
AA seq
682 aa
AA seq
DB search
MFFNRLSAGKLLVPLSVVLYALFVVILPLQNSFHSSNVLVRGADDVENYGTVIGIDLGTT
YSCVAVMKNGKTEILANEQGNRITPSYVAFTDDERLIGDAAKNQVAANPQNTIFDIKRLI
GLKYNDRSVQKDIKHLPFNVVNKDGKPAVEVSVKGEKKVFTPEEISGMILGKMKQIAEDY
LGTKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLDKSDKEHQI
IVYDLGGGTFDVSLLSIENGVFEVQATSGDTHLGGEDFDYKIVRQLIKAFKKKHGIDVSD
NNKALAKLKREAEKAKRALSSQMSTRIEIDSFVDGIDLSETLTRAKFEELNLDLFKKTLK
PVEKVLQDSGLEKKDVDDIVLVGGSTRIPKVQQLLESYFDGKKASKGINPDEAVAYGAAV
QAGVLSGEEGVEDIVLLDVNALTLGIETTGGVMTPLIKRNTAIPTKKSQIFSTAVDNQPT
VMIKVYEGERAMSKDNNLLGKFELTGIPPAPRGVPQIEVTFALDANGILKVSATDKGTGK
SESITITNDKGRLTQEEIDRMVEEAEKFASEDASIKAKVESRNKLENYAHSLKNQVNGDL
GEKLEEEDKETLLDAANDVLEWLDDNFETAIAEDFDEKFESLSKVAYPITSKLYGGADGS
GAADYDDEDEDDDGDYFEHDEL
NT seq
2049 nt
NT seq
+upstream
nt +downstream
nt
atgtttttcaacagactaagcgctggcaagctgctggtaccactctccgtggtcctgtac
gcccttttcgtggtaatattacctttacagaattctttccactcctccaatgttttagtt
agaggtgccgatgatgtagaaaactacggaactgttatcggtattgacttaggtactact
tattcctgtgttgctgtgatgaaaaatggtaagactgaaattcttgctaatgagcaaggt
aacagaatcaccccatcttacgtggcattcaccgatgatgaaagattgattggtgatgct
gcaaagaaccaagttgctgccaatcctcaaaacaccatcttcgacattaagagattgatc
ggtttgaaatataacgacagatctgttcagaaggatatcaagcacttgccatttaatgtg
gttaataaagatgggaagcccgctgtagaagtaagtgtcaaaggagaaaagaaggttttt
actccagaagaaatttctggtatgatcttgggtaagatgaaacaaattgccgaagattat
ttaggcactaaggttacccatgctgtcgttactgttcctgcttatttcaatgacgcgcaa
agacaagccaccaaggatgctggtaccatcgctggtttgaacgttttgagaattgttaat
gaaccaaccgcagccgccattgcctacggtttggataaatctgataaggaacatcaaatt
attgtttatgatttgggtggtggtactttcgatgtctctctattgtctattgaaaacggt
gttttcgaagtccaagccacttctggtgatactcatttaggtggtgaagattttgactat
aagatcgttcgtcaattgataaaagctttcaagaagaagcatggtattgatgtgtctgac
aacaacaaggccctagctaaattgaagagagaagctgaaaaggctaaacgtgccttgtcc
agccaaatgtccacccgtattgaaattgactccttcgttgatggtatcgacttaagtgaa
accttgaccagagctaagtttgaggaattaaacctagatctattcaagaagaccttgaag
cctgtcgagaaggttttgcaagattctggtttggaaaagaaggatgttgatgatatcgtt
ttggttggtggttctactagaattccaaaggtccaacaattgttagaatcatactttgat
ggtaagaaggcctccaagggtattaacccagatgaagctgttgcatacggtgcagccgtt
caagctggtgtcttatccggtgaagaaggtgtcgaagatattgttttattggatgtcaac
gctttgactcttggtattgaaaccactggtggtgtcatgactccattaattaagagaaat
actgctattcctacaaagaaatcccaaattttctctactgccgttgacaaccaaccaacc
gttatgatcaaggtatacgagggtgaaagagccatgtctaaggacaacaatctattaggt
aagtttgaattaaccggcattccaccagcaccaagaggtgtacctcaaattgaagtcaca
tttgcacttgacgctaatggtattctgaaggtgtctgccacagataagggaactggtaaa
tccgaatctatcaccatcactaacgataaaggtagattaacccaagaagagattgataga
atggttgaagaggctgaaaaattcgcttctgaagacgcttctatcaaggccaaggttgaa
tctagaaacaaattagaaaactacgctcactctttgaaaaaccaagttaatggtgaccta
ggtgaaaaattggaagaagaagacaaggaaaccttattagatgctgctaacgatgtttta
gaatggttagatgataactttgaaaccgccattgctgaagactttgatgaaaagttcgaa
tctttgtccaaggtcgcttatccaattacttctaagttgtacggaggtgctgatggttct
ggtgccgctgattatgacgacgaagatgaagatgacgatggtgattatttcgaacacgac
gaattgtag
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