Saccharomyces cerevisiae (budding yeast): YJR139C
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Entry
YJR139C CDS
T00005
Symbol
HOM6, THR6
Name
(RefSeq) homoserine dehydrogenase
KO
K00003
homoserine dehydrogenase [EC:
1.1.1.3
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00260
Glycine, serine and threonine metabolism
sce00270
Cysteine and methionine metabolism
sce00300
Lysine biosynthesis
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01230
Biosynthesis of amino acids
Module
sce_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sce_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
YJR139C (HOM6)
00270 Cysteine and methionine metabolism
YJR139C (HOM6)
00300 Lysine biosynthesis
YJR139C (HOM6)
Enzymes [BR:
sce01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
YJR139C (HOM6)
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Motif
Pfam:
Homoserine_dh
NAD_binding_3
DUF5101
Motif
Other DBs
NCBI-GeneID:
853604
NCBI-ProteinID:
NP_012673
SGD:
S000003900
UniProt:
P31116
Structure
PDB
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Position
X:complement(689445..690524)
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AA seq
359 aa
AA seq
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MSTKVVNVAVIGAGVVGSAFLDQLLAMKSTITYNLVLLAEAERSLISKDFSPLNVGSDWK
AALAASTTKTLPLDDLIAHLKTSPKPVILVDNTSSAYIAGFYTKFVENGISIATPNKKAF
SSDLATWKALFSNKPTNGFVYHEATVGAGLPIISFLREIIQTGDEVEKIEGIFSGTLSYI
FNEFSTSQANDVKFSDVVKVAKKLGYTEPDPRDDLNGLDVARKVTIVGRISGVEVESPTS
FPVQSLIPKPLESVKSADEFLEKLSDYDKDLTQLKKEAATENKVLRFIGKVDVATKSVSV
GIEKYDYSHPFASLKGSDNVISIKTKRYTNPVVIQGAGAGAAVTAAGVLGDVIKIAQRL
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atgagcactaaagttgttaatgttgccgttatcggtgccggtgttgttggttcagctttc
ttggatcaattgttagccatgaagtctaccattacttacaatctagttcttttggctgaa
gctgagcgttctttaatctccaaggacttttctccattaaatgttggttctgattggaag
gctgctttagcagcctccactactaaaacgttgcctttggatgatttaattgctcatttg
aagacttcacctaagccagtcattttggttgataacacttccagcgcttacattgctggt
ttttacactaagtttgtcgaaaatggtatttccattgctactccaaacaagaaggccttt
tcctctgatttggctacctggaaggctcttttctcaaataagccaactaacggttttgtc
tatcatgaagctaccgtcggtgctggtttgcctatcatcagtttcttaagagaaattatt
caaaccggtgacgaagttgaaaaaattgaaggtatcttctctggtactctatcttatatt
ttcaacgagttctccactagtcaagctaacgacgtcaaattctctgatgttgtcaaagtt
gctaaaaaattgggttatactgaaccagatccaagagatgatttgaatgggttggatgtt
gctagaaaggttaccattgttggtaggatatctggtgtggaagttgaatctccaacttcc
ttccctgtccagtctttgattccaaaaccattggaatctgtcaagtctgctgatgaattc
ttggaaaaattatctgattacgataaagatttgactcaattgaagaaggaagctgccact
gaaaataaggtattgagattcattggtaaagtcgatgttgccaccaaatctgtgtctgta
ggaattgaaaagtacgattactcacacccattcgcatcattgaagggatcagataacgtt
atttccatcaagactaagcgttacaccaatcctgttgtcattcaaggtgccggtgccggt
gctgccgttactgccgctggtgttttgggtgatgttatcaagattgctcaaagactttag
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