Saccharomyces cerevisiae (budding yeast): YNL104C
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Entry
YNL104C CDS
T00005
Symbol
LEU4
Name
(RefSeq) 2-isopropylmalate synthase LEU4
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00290
Valine, leucine and isoleucine biosynthesis
sce00620
Pyruvate metabolism
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01210
2-Oxocarboxylic acid metabolism
sce01230
Biosynthesis of amino acids
Module
sce_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
YNL104C (LEU4)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
YNL104C (LEU4)
Enzymes [BR:
sce01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
YNL104C (LEU4)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
CGI-121
Motif
Other DBs
NCBI-GeneID:
855619
NCBI-ProteinID:
NP_014295
SGD:
S000005048
UniProt:
P06208
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Position
XIV:complement(424895..426754)
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AA seq
619 aa
AA seq
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MVKESIIALAEHAASRASRVIPPVKLAYKNMLKDPSSKYKPFNAPKLSNRKWPDNRITRA
PRWLSTDLRDGNQSLPDPMSVEQKKEYFHKLVNIGFKEIEVSFPSASQTDFDFTRYAVEN
APDDVSIQCLVQSREHLIKRTVEALTGAKKATIHTYLATSDMFREIVFNMSREEAISKAV
EATKLVRKLTKDDPSQQATRWSYEFSPECFSDTPGEFAVEICEAVKKAWEPTEENPIIFN
LPATVEVASPNVYADQIEYFATHITEREKVCISTHCHNDRGCGVAATELGMLAGADRVEG
CLFGNGERTGNVDLVTVAMNMYTQGVSPNLDFSDLTSVLDVVERCNKIPVSQRAPYGGDL
VVCAFSGSHQDAIKKGFNLQNKKRAQGETQWRIPYLPLDPKDIGRDYEAVIRVNSQSGKG
GAAWVILRSLGLDLPRNMQIEFSSAVQDHADSLGRELKSDEISKLFKEAYNYNDEQYQAI
SLVNYNVEKFGTERRVFTGQVKVGDQIVDIEGTGNGPISSLVDALSNLLNVRFAVANYTE
HSLGSGSSTQAASYIHLSYRRNADNEKAYKWGVGVSEDVGDSSVRAIFATINNIIHSGDV
SIPSLAEVEGKNAAASGSA
NT seq
1860 nt
NT seq
+upstream
nt +downstream
nt
atggttaaagagagtattattgctcttgctgagcatgcggcctccagagcctcaagagtt
attcctccagtgaagctagcctataaaaatatgcttaaggacccttcctccaagtacaag
ccatttaacgctccaaagctatctaatagaaagtggccggataaccggatcacgagggct
cctcgttggttatcaacagatttgagagatggtaaccaatctctgccggatcccatgtca
gtggaacaaaagaaagaatactttcacaagctggtcaatattgggttcaaagaaatcgag
gtttccttcccctctgcatctcaaacagatttcgacttcactagatatgctgtagaaaac
gccccagacgatgttagtattcaatgtcttgtccaatctagagaacacttgattaagaga
acggtggaagcattaacaggtgctaaaaaggctactatacatacttacttggcaacaagt
gatatgttccgtgaaattgtttttaatatgtctagagaggaagctatttccaaggcagta
gaggccaccaaactagttaggaaactaactaaggatgacccttcccaacaagccactcgt
tggtcctatgagttttcccccgaatgtttcagtgatactccaggtgaatttgctgtagaa
atttgcgaagctgttaagaaggcttgggaacctaccgaggaaaatccaatcattttcaac
ttacctgctaccgtagaagttgcctctccaaatgtttatgctgatcagattgaatacttc
gctacccatattactgagcgtgagaaggtttgcatctctacacattgtcacaatgaccgt
ggttgcggtgtcgccgccacagagttaggtatgcttgcaggtgccgaccgtgtagaagga
tgtctctttggtaatggtgaacgtacaggtaatgtggacttggttactgttgctatgaat
atgtatacccaaggtgtttctcctaatttggatttctctgacttgacctctgtcctagat
gtggttgagcgttgtaataagatcccagtatcgcaaagagcaccatacggcggtgacttg
gtcgtttgtgccttttccggttctcaccaagacgccattaagaagggtttcaacttacaa
aacaagaagcgtgctcaaggtgaaactcaatggagaatcccatacttgccattggatcca
aaggacattggccgtgattacgaagctgtcatcagagtcaactctcagtctggtaaaggt
ggtgccgcttgggttattttgagatctttgggtttggatctaccaagaaacatgcaaatc
gaattttctagcgccgttcaagaccatgctgactccttgggtagagaactaaaatcagat
gagatttccaagttattcaaagaggcttacaactacaatgacgaacagtaccaagctatt
agtttagtcaattataatgttgaaaaattcggcactgaacgtagagtgttcactggtcaa
gtcaaagtaggcgaccagatcgtcgatattgaaggtacaggtaatggtccaatctcttct
ttggtcgacgccctatcaaacttgttgaacgtgagatttgccgtagcaaactacacagag
cattctctaggttctggttcttctacgcaagctgcttcttacatccatctatcgtatagg
cgtaatgccgacaacgaaaaggcctacaaatggggtgtaggtgtctccgaagatgtcggt
gattcttcagtgagagccatctttgccaccattaacaatattatccattctggtgatgtg
tccattccatctttggccgaggtcgaaggtaagaatgctgcggcatctggctctgcataa
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