Saccharomyces cerevisiae (budding yeast): YNL262W
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Entry
YNL262W CDS
T00005
Symbol
POL2, DUN2
Name
(RefSeq) DNA polymerase epsilon catalytic subunit
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce03030
DNA replication
sce03410
Base excision repair
sce03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
YNL262W (POL2)
03410 Base excision repair
YNL262W (POL2)
03420 Nucleotide excision repair
YNL262W (POL2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
sce03032
]
YNL262W (POL2)
03400 DNA repair and recombination proteins [BR:
sce03400
]
YNL262W (POL2)
Enzymes [BR:
sce01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
YNL262W (POL2)
DNA replication proteins [BR:
sce03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
YNL262W (POL2)
DNA repair and recombination proteins [BR:
sce03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
YNL262W (POL2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
zf_DPOE_2
NAPRTase_C
Cytochrom_c3_2
zf-DNA_Pol
Motif
Other DBs
NCBI-GeneID:
855459
NCBI-ProteinID:
NP_014137
SGD:
S000005206
UniProt:
P21951
Structure
PDB
PDBj
LinkDB
All DBs
Position
XIV:148212..154880
Genome browser
AA seq
2222 aa
AA seq
DB search
MMFGKKKNNGGSSTARYSAGNKYNTLSNNYALSAQQLLNASKIDDIDSMMGFERYVPPQY
NGRFDAKDIDQIPGRVGWLTNMHATLVSQETLSSGSNGGGNSNDGERVTTNQGISGVDFY
FLDEEGGSFKSTVVYDPYFFIACNDESRVNDVEELVKKYLESCLKSLQIIRKEDLTMDNH
LLGLQKTLIKLSFVNSNQLFEARKLLRPILQDNANNNVQRNIYNVAANGSEKVDAKHLIE
DIREYDVPYHVRVSIDKDIRVGKWYKVTQQGFIEDTRKIAFADPVVMAFDIETTKPPLKF
PDSAVDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKPEYPGFFTIFNENDEVALLQ
RFFEHIRDVRPTVISTFNGDFFDWPFIHNRSKIHGLDMFDEIGFAPDAEGEYKSSYCSHM
DCFRWVKRDSYLPQGSQGLKAVTQSKLGYNPIELDPELMTPYAFEKPQHLSEYSVSDAVA
TYYLYMKYVHPFIFSLCTIIPLNPDETLRKGTGTLCEMLLMVQAYQHNILLPNKHTDPIE
RFYDGHLLESETYVGGHVESLEAGVFRSDLKNEFKIDPSAIDELLQELPEALKFSVEVEN
KSSVDKVTNFEEIKNQITQKLLELKENNIRNELPLIYHVDVASMYPNIMTTNRLQPDSIK
AERDCASCDFNRPGKTCARKLKWAWRGEFFPSKMDEYNMIKRALQNETFPNKNKFSKKKV
LTFDELSYADQVIHIKKRLTEYSRKVYHRVKVSEIVEREAIVCQRENPFYVDTVKSFRDR
RYEFKGLAKTWKGNLSKIDPSDKHARDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSR
WYSMEMAGITCLTGATIIQMARALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGKK
LYLSYPCSMLNYRVHQKFTNHQYQELKDPLNYIYETHSENTIFFEVDGPYKAMILPSSKE
EGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVA
SVCNRWLDVLDSHGLMLEDEDLVSLICENRSMSKTLKEYEGQKSTSITTARRLGDFLGED
MVKDKGLQCKYIISSKPFNAPVTERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTI
IDWGYYRERLGSAIQKIITIPAALQGVSNPVPRVEHPDWLKRKIATKEDKFKQTSLTKFF
SKTKNVPTMGKIKDIEDLFEPTVEEDNAKIKIARTTKKKAVSKRKRNQLTNEEDPLVLPS
EIPSMDEDYVGWLNYQKIKWKIQARDRKRRDQLFGNTNSSRERSALGSMIRKQAESYANS
TWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSS
ASLPNNPKTSNPAGGQLFKITLPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMD
LGASVTFRSKAMGALGKGIQQGFEMKDLSMAENERYLSGFSMDIGYLLHFPTSIGYEFFS
LFKSWGDTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEF
VYFTDISKLYRRLSQETTKLKEERGLQFLLLLQSPFITKLLGTIRLLNQMPIVKLSLNEV
LLPQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSMDYIIDVLYARKL
KKENIVLWWNEKAPLPDHGGIQNDFDLNTSWIMNDSEFPKINNSGVYDNVVLDVGVDNLT
VNTILTSALINDAEGSDLVNNNMGIDDKDAVINSPSEFVHDAFSNDALNVLRGMLKEWWD
EALKENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVY
ADRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGL
ACIEIEEKENQDYTAVSQWQLKKFLSPIYQPEFEDWMMIILDSMLKTKQSYLKLNSGTQR
PTQIVNVKKQDKEDSVENSLNGFSHLFSKPLMKRVKKLFKNQQEFILDPQYEADYVIPVL
PGSHLNVKNPLLELVKSLCHVMLLSKSTILEIRTLRKELLKIFELREFAKVAEFKDPSLS
LVVPDFLCEYCFFISDIDFCKAAPESIFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQ
DLRCSRCHKVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIADL
TI
NT seq
6669 nt
NT seq
+upstream
nt +downstream
nt
atgatgtttggcaagaaaaaaaacaacggaggatcttccactgcaagatattcagctggc
aacaagtacaacacactctcaaataattatgcgcttagcgcgcaacagctcttaaatgct
agtaagatcgatgacatcgattcgatgatgggatttgaaagatacgtaccgccgcaatac
aatggcaggtttgatgcgaaggatatagatcagattccaggccgcgtagggtggctgacg
aacatgcacgcaacgctggtctctcaggaaaccttatccagtggtagtaatggcggcggc
aattcgaatgacggagaacgtgtaacgaccaaccaaggtatttccggagttgacttctac
tttttagatgaagagggtgggagcttcaagtcgacagttgtctatgacccatacttcttt
attgcgtgtaacgatgaatcaagagtaaatgatgtggaggaactagtgaaaaaatatctg
gaatcttgtctcaaaagcttacaaatcattagaaaggaagatcttaccatggacaatcac
cttttagggctgcagaagacacttattaagttatcatttgtaaattccaatcagttattc
gaggccaggaaactcctgaggccaatcttgcaggataatgccaataataatgtgcaaaga
aatatatataacgttgctgcaaatggctcggaaaaagttgacgccaaacatctgatcgaa
gatatcagggaatatgatgtgccgtatcatgtccgagtatctatagacaaggacattaga
gtcggtaaatggtataaggtaactcaacagggattcattgaagatactaggaaaattgca
tttgccgaccctgtggtaatggcatttgatatagaaaccacgaagccgcctttaaaattc
ccggattccgccgtagatcaaataatgatgatttcgtatatgatcgatggggaaggtttt
ttgataacaaatagggagataatctctgaggatattgaagactttgagtatacaccgaaa
ccggagtatcctggttttttcaccatatttaacgaaaacgatgaagtggcgcttctacaa
aggttttttgaacatataagagatgtacgacccactgttatatccaccttcaatggtgac
tttttcgattggccttttatacataacagaagtaagattcacggcttggacatgttcgat
gaaattggtttcgctccagatgctgaaggtgagtacaagtcctcatactgctctcacatg
gattgtttccgttgggtgaagcgtgattcttatttaccacaaggttcccagggtttaaaa
gctgttactcaatctaagctaggttataacccaattgaactggatcccgaattaatgacg
ccgtatgcatttgaaaagccacagcacctttccgaatattctgtttccgatgcagtcgct
acgtattacctttacatgaaatatgttcatccttttatcttttccctttgtactattatt
cctttgaacccggatgaaacattgagaaagggtaccggtactttgtgtgaaatgttgttg
atggttcaagcttatcaacataatattcttctaccaaataagcatacagatcccattgag
aggttctatgatggacatcttctagaatccgagacttacgtgggtggacatgtggagtca
ttagaagctggtgtttttaggagtgatttgaagaatgaattcaagatagatccttctgcc
attgatgaattattacaagaattaccagaagctttgaaatttagtgtggaagttgaaaat
aagtccagtgtagataaagtaacgaattttgaggaaataaaaaaccagataacgcagaaa
ttattagagttgaaggaaaacaatataagaaacgaactacctttgatctatcatgtagat
gtcgcctctatgtacccaaacatcatgactacaaatagactacaaccagatagtatcaaa
gcagagcgcgattgtgctagttgcgattttaatagacccggaaaaacctgtgcaagaaag
ttaaaatgggcttggagaggagaattctttcccagtaagatggatgagtataacatgatc
aagcgtgcattacaaaatgagacttttcccaacaaaaacaagttttctaaaaagaaagtt
ttgacatttgatgaactaagttacgcagaccaagttatccacataaaaaaacgtttaact
gaatattcaaggaaagtttatcatagggttaaagtatcagaaattgtcgaacgagaagcc
attgtctgccaaagagaaaatccattctacgtcgataccgtgaaatcctttcgtgatagg
cgttacgaattcaaaggtttagccaagacttggaagggaaatctgtccaaaattgaccca
tctgataagcatgcgagagacgaggccaaaaagatgattgtgctttatgactcattacaa
ttagctcacaaagttattttgaattcgttttatgggtatgttatgaggaaaggctctcgt
tggtattccatggaaatggcggggattacgtgtttaacaggtgccacgatcattcaaatg
gcgagagctttagtagaaagggtaggaagaccattagaattagatactgatggtatttgg
tgtatcttaccaaaatctttccctgaaacttacttttttacattagaaaatggtaaaaag
ctttatctctcctacccatgttccatgctgaattacagagttcaccaaaagtttacgaat
caccaataccaagaattaaaagacccattgaactatatatatgagacgcacagtgaaaac
acgatttttttcgaagttgacggaccatataaggccatgattttgcctagttccaaggaa
gaaggaaaaggtataaagaaaagatatgctgtcttcaatgaagacggctcacttgctgaa
ctgaaaggttttgaattgaagaggcgtggtgaattacaactaataaaaaattttcaaagt
gatattttcaaggtctttttggaaggtgatacattagaaggatgttacagtgctgtagca
agcgtatgtaaccgttggttagatgttcttgattcacatggtcttatgttagaagatgaa
gacttggtcagtttgatttgtgaaaatagaagtatgtcaaaaactttaaaggaatatgaa
gggcaaaaatctacttctattacgacggcaaggagattgggggattttttgggtgaagat
atggtaaaagataaaggtctacaatgtaaatatattattagttcaaaacctttcaatgca
cctgttactgaacgagccattccagtcgcaatattttcagcggacattcccatcaaaagg
tcttttctgaggcgatggacattagatccatctttggaagatctggatatcagaaccata
atcgattggggttattatagagaaagacttggatctgctatacaaaagataattactatt
ccagcagcattacaaggggtttccaatcctgttccaagggttgaacatccagattggcta
aaaagaaaaatcgctacaaaggaggataagtttaagcagacttcactaaccaaatttttt
tcgaagacaaagaatgtaccaacaatgggcaagataaaagatatcgaggatttgtttgaa
ccaactgtagaagaagataacgccaaaattaaaattgcaagaactactaaaaagaaagcc
gtatccaagaggaaaagaaatcagcttacaaatgaagaagatccactagtattgccctcg
gagattccttccatggacgaggactatgttgggtggctaaattatcaaaaaattaaatgg
aaaatccaagcaagagatagaaagcgtcgagaccaattatttggtaatacaaacagctcc
cgtgaaagaagtgcactaggaagtatgattaggaagcaagctgaatcatatgcgaactcc
acttgggaggtcttacaatacaaggattccggtgagccaggggttttggaagtatttgta
acaattaatggcaaagtccagaacatcaccttccatataccaaaaactatttatatgaaa
ttcaaatctcaaacaatgccgctacaaaagattaagaattgccttattgaaaaatcttct
gcatcgttaccaaataatcccaaaacgtctaatccagcaggcggtcagctattcaaaatt
actctaccggaatctgtctttctggaagaaaaggaaaactgcactagtatcttcaacgat
gaaaatgtacttggtgtatttgagggcactatcactcctcatcaaagagcgatcatggat
ttgggagcttcggtaacgttccgctcaaaagcaatgggtgcgttaggcaagggaatacag
cagggttttgaaatgaaggatctttcaatggcggaaaatgaaaggtatctgagtggattt
tcaatggacattggctatttactacatttcccaacatcaattgggtatgaatttttttca
ttattcaagtcatggggagatactattactatattagttttgaaaccatccaaccaggct
caggaaataaatgcctcatcattaggacaaatatacaaacaaatgtttgaaaaaaagaaa
ggtaaaatagaaacatattcttacttggttgatattaaagaagatatcaattttgagttt
gtatattttacagatatctcaaaattgtacagaagactatcacaggaaactactaaatta
aaagaagaaagaggtctgcagtttttactcttgttacaatctccgtttatcactaagctc
ttaggcacaatccggcttctaaaccagatgcccattgttaagctttccttgaatgaagtt
cttctaccccaattgaactggcaaccgacattattgaagaaacttgttaaccacgtttta
tccagtggttcgtggatttctcacttgatcaagttatcccagtatagtaacattccaatc
tgtaatttgaggctggatagtatggattatattattgatgttctttatgcaagaaaacta
aaaaaagagaacatcgtgctttggtggaatgagaaagctccacttccagatcatggaggc
attcaaaatgattttgatttaaatacatcatggataatgaatgattcagaatttcccaaa
attaataactcaggtgtgtatgacaatgtagttctcgatgttggtgttgataatttaaca
gtgaacacaattttgacatcagcattaatcaatgatgctgaaggcagtgatctagttaac
aataatatgggtatagatgacaaagatgccgttattaactcgccatctgaattcgtgcac
gacgccttttctaatgacgctttgaatgttttaagaggtatgttaaaggagtggtgggat
gaggccctaaaagaaaattcaaccgcagatttgttggtaaattccctggcaagttgggtt
caaaacccgaatgcgaaactattcgacggattactaagatatcacgttcataacttaaca
aaaaaagccttacttcaattagtaaatgaatttagtgcacttggctcaactattgtatat
gcagacaggaatcaaattctaataaagacaaacaagtactcacctgaaaactgttacgcc
tacagccaatatatgatgaaggcagttagaacaaatccaatgtttagttatctggactta
aatatcaaacgttattgggatctgctaatatggatggataagtttaattttagtggatta
gcatgtattgaaatagaggaaaaggaaaatcaggattataccgctgtttcgcaatggcaa
ctaaagaagtttctgtcaccaatatatcagcccgaatttgaggattggatgatgatcata
ttggatagtatgctaaagacaaagcagagctatctaaaattgaattcagggacgcaaaga
cctacccaaatagttaatgtaaaaaaacaagataaggaagatagtgttgaaaactcgttg
aacggattttctcaccttttttccaaaccactaatgaaaagagtcaaaaagctttttaaa
aaccagcaagagttcattttagatcctcagtatgaggcagactatgttattcctgttctt
cctggttcccatctgaatgtgaaaaatccccttctagaacttgtcaaatcactctgccat
gtcatgttactttcaaagagtacaattttagaaatcaggaccctgagaaaagaactgctg
aagatatttgaattgcgtgagtttgctaaagtagcggaattcaaagatccaagtttgagt
ctcgtggtgccggattttttatgtgaatactgttttttcatttctgatattgacttttgt
aaggcagctcctgaatctattttttcatgcgtcagatgtcacaaagcctttaatcaagta
ttgttgcaagaacacctgattcaaaaactacgttctgatatcgaatcctatttaattcaa
gatttgagatgctccagatgtcataaagtgaaacgtgactatatgagtgcccactgtcca
tgtgccggcgcgtgggaaggaactctccccagagaaagcattgttcaaaagttaaatgtg
tttaagcaagtagccaagtattacggttttgatatattattgagttgtattgctgatttg
accatatga
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