Saccharomyces cerevisiae (budding yeast): YPR006C
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Entry
YPR006C CDS
T00005
Symbol
ICL2
Name
(RefSeq) methylisocitrate lyase ICL2
KO
K01637
isocitrate/methylisocitrate lyase [EC:
4.1.3.1
4.1.3.30
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00630
Glyoxylate and dicarboxylate metabolism
sce00640
Propanoate metabolism
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01200
Carbon metabolism
Module
sce_M00012
Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
YPR006C (ICL2)
00640 Propanoate metabolism
YPR006C (ICL2)
Enzymes [BR:
sce01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.1 isocitrate lyase
YPR006C (ICL2)
4.1.3.30 methylisocitrate lyase
YPR006C (ICL2)
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Gene cluster
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Motif
Pfam:
ICL
PEP_mutase
Motif
Other DBs
NCBI-GeneID:
856114
NCBI-ProteinID:
NP_015331
SGD:
S000006210
UniProt:
Q12031
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Position
XVI:complement(567269..568996)
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AA seq
575 aa
AA seq
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MITMINNKTFNRKTTGTLKKLVLSSDKSLRRSFNGASSTKDFVFSESSKVEEWWESARFK
NISRPYSATDVVKHRGSLPANTSIYPSSYQARKLFNLLEENFKNGTPLHTLGVIDPVQMS
QLARCRNIKVAYISGWACSSTLVGSTNEVSPDFGDYPYDTVPNQVERIFKAQQLHDRKAF
LEASIKGSTPVDYLKPIIADADMGHGGPTTVMKVAKLFAEKGAAGIHLEDQMVGGKRCGH
LSGAVLVPTATHLMRLISTRFQWDIMGTENLVIARTDSCNGKLLSSSSDPRDHEFIRGII
RDNVVPWSEKLIEMEDKKIPNSAIADMEKEWYHENELFTFEEALEKQFTASEFESYKEKK
EDLMVNKLGRAYLSLREMKLLAQEVTPLKKIIFDWDAPRTKEGYYMFNGCIEAAIRRSLV
FAPYSDMIWLETKTPDLEQARSFSRKIHKQLPATKLVYNLSPSFNWSAHGFDDKALKSFV
WDLAKEGFTLQLVSLAGLHSDGVSFWELANSFQSDGMKAYVEKVQKREKETNCDIMTHQL
WSGAEYVDSLMKVVQNGASSQTLSTSGESFTETQF
NT seq
1728 nt
NT seq
+upstream
nt +downstream
nt
atgattacaatgattaacaacaaaactttcaatagaaaaactacgggaacactgaagaag
ctggttttgtcatcagacaagtcactgcgaagatctttcaacggggcaagcagtactaaa
gacttcgtgttctcggaatcaagtaaagtagaagaatggtgggaatcagccagatttaag
aatatcagtcgtccatactcagctacggatgttgtaaagcatcggggcagccttcctgct
aatacttcaatttatccttcatcttatcaagctcgaaagctgttcaacttactagaagag
aatttcaagaatggtactccacttcacacgttgggagttatcgatcctgtacaaatgagt
cagttggcccgttgcagaaatatcaaagttgcttacatatctggttgggcttgttcttcc
acattagttggatctacaaatgaagtatcgccggattttggcgattatccatacgatact
gtgccgaatcaagtggagagaatattcaaggcgcagcaattgcacgatcgaaaggctttc
ttggaggcctccatcaaaggttctactcctgttgattatttaaaaccaattatcgcggac
gcagacatgggtcacggtggcccaacgactgtaatgaaagttgctaagttgtttgcggag
aaaggggctgctggtattcatcttgaagatcagatggtgggaggcaaaaggtgtggccat
ctaagtggggctgttttggtgcccacagcaacacatcttatgagattgatttccaccagg
tttcaatgggatatcatggggacagaaaatttggttattgcaagaacagattcctgtaat
ggtaagctgttgagttcaagcagtgatccgagagaccacgaattcattaggggtataata
agagataacgtggtgccttggagcgaaaaattgattgagatggaggacaaaaaaattccc
aactccgccattgctgacatggaaaaagaatggtaccatgaaaatgagctgtttacattt
gaagaggccttagaaaagcagtttacggcaagcgagtttgaaagctataaagaaaagaag
gaagaccttatggtaaacaagctgggtagagcatacctaagcttaagagaaatgaaactt
ttagctcaagaagtgacaccactaaagaaaattatatttgactgggatgctccgaggacc
aaagagggatattacatgtttaacggttgtattgaagcagctattagaagatctttggtg
tttgccccatattctgatatgatttggctggaaacgaaaactcctgacctggagcaggca
cgctcattttcaagaaaaattcataaacaacttccagctaccaagctagtatataactta
tctcctagtttcaattggagcgctcacggctttgatgataaggcattaaaatccttcgta
tgggacttggcaaaagaaggcttcacgttgcaactggtttcccttgccggtctgcattca
gatggagtatcattctgggaattagccaatagcttccaaagtgacggaatgaaagcatac
gtcgaaaaagtgcaaaaacgggaaaaggagactaattgtgatatcatgacacaccagcta
tggtctggtgcagaatatgttgattccttaatgaaagttgtccaaaacggtgcttcatcc
caaactttaagtacatctggtgagagctttaccgaaacgcaattttga
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