Squalius cephalus (European chub): 307149272
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Entry
307149272 CDS
T11930
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
scep Squalius cephalus (European chub)
Pathway
scep00270
Cysteine and methionine metabolism
scep00480
Glutathione metabolism
scep01100
Metabolic pathways
scep01240
Biosynthesis of cofactors
scep04216
Ferroptosis
Module
scep_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
scep00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
307149272 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
307149272 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
307149272 (gclc)
Enzymes [BR:
scep01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
307149272 (gclc)
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Other DBs
NCBI-GeneID:
307149272
NCBI-ProteinID:
XP_079711635
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Position
21:complement(2931018..2971467)
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AA seq
631 aa
AA seq
DB search
MGLLSQGSPLNWEETKKHADHVRKHGILQFLNIYNKVKERQKDVLKWGDEVEYMLVEMDD
KHEKARLVLNGKEVLEILQEKGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMGKRRREASSVLDLNQTLLTVTAFPRLGCPGFTLPEHKPTPVEKGVSKSLFFPDEAI
NTHPRFSTLTRNIRHRRGEKVAINVPIFKDKNTPSPFVETFAEDDGEAARGALPDHIYMD
AMGFGMGNCCLQVTFQACSIREARYLYDQLAVFCPIVMALSAASPLYRGLVSDIDCRWGV
ISASVDDRTREERGLEPLKNNKFKINKSRYDSIDSYLSCCGEKYNDIELTIDEEINKQLL
DAGIDKLLAQHIAHLFIRDPLSLFQEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFIVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
QEGMFYFRKDVFKGCNPVLDQPSAAQNGVESDASDGEEFTLMSIDTIINGKEGVFHGLIP
MLNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVSKHPQYKQDSVITDK
INYDLLHKCDRIAKGEEKCPELIGEPVNRGK
NT seq
1896 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgtcacaaggctcaccgctcaactgggaagagaccaagaaacatgctgac
cacgttaggaagcacggcatccttcagttcctcaacatctacaacaaggtgaaggagcga
cagaaggatgtgctgaaatggggagatgaggtggagtacatgttggtggaaatggatgac
aaacatgaaaaagcccgtctggttctgaacgggaaggaggttttggaaatccttcaggaa
aagggtgaaaagatcaaccccaaccacccgacgctgtggaggccggagtacggcagctac
atgatcgaaggcacgccgggacagccgtacgggggcacgatgtcggagttcaacaccgtc
gaggacaacatggggaagcggaggagagaggcgtcgtctgtgctcgatctgaaccagact
ctcctcacagtcaccgcgttccccaggttaggctgcccaggcttcacactgccagaacac
aaacccacacctgttgaaaaaggggtgtcgaaatctctcttcttccccgacgaggccatc
aacacacaccccagattcagcactctgaccagaaacatacgccaccggaggggcgagaag
gtggcgattaacgtaccaattttcaaagataaaaacaccccgtctccgtttgtggagacg
ttcgcggaggacgatggagaagcggcccggggagccctgcccgatcacatctacatggac
gccatgggcttcggcatgggcaactgttgcctgcaggtgaccttccaggcttgcagcatc
agggaggcgcgctacctctacgaccaactggccgttttctgtccaatagtgatggctctc
agtgccgcctctccgctctatcgcggactggtttcagacatcgactgccgttggggtgtg
atctctgcatctgtggacgaccggacccgagaggagagaggcctggagccgctgaaaaac
aacaaattcaagatcaataaatccaggtatgattcgattgacagctacctctcctgctgc
ggcgagaaatacaacgacatcgagctgaccatcgatgaggagatcaacaagcagctcctc
gatgcaggcattgacaaactgctggcccagcacatcgcacacctcttcatccgagacccg
ctgtcgctcttccaggagaagattcacttggacgacgagaacgaatcggaccacttcgag
aatcttcagtcaaccaactggcagacaatgaggttcaagcccccccctccgaactctgac
atcggctggagagtcgagtttcggcccatggaggttcaactgacagattttgagaactct
gcttatgtcgtattcatcgttcttctcacccgtgtgatcttgtcctataagctggatttc
ctcattccattatcaaaggtcgatgaaaatatgaaagttgcccagaagcgaaatgccgtg
caagaaggcatgttttattttcggaaggacgtctttaaaggctgtaacccagtgttggac
cagccgtccgcggctcagaacggggtggagagcgacgccagtgacggggaagagttcaca
ctgatgagcatcgacaccatcatcaacgggaaggaaggggtgtttcacgggctgatcccg
atgttgaacagctacctggagaacatggaggtggacgtcgacacgcggtgcacgatcctc
aactatctgaaactcattaagaagcgcgcctctggtgagctgatgactatggcgaagtgg
atgagggagtttgtgtccaaacaccctcagtacaagcaggacagtgtcattacagacaaa
atcaactacgacctgctgcacaagtgcgaccggatcgccaagggggaggagaagtgtccc
gagctgatcggagagccggtgaacagggggaaataa
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