Streptomyces chartreusis: CP983_18595
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Entry
CP983_18595 CDS
T07157
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
scha
Streptomyces chartreusis
Pathway
scha00860
Porphyrin metabolism
scha01100
Metabolic pathways
scha01110
Biosynthesis of secondary metabolites
scha01120
Microbial metabolism in diverse environments
scha01240
Biosynthesis of cofactors
Module
scha_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
scha_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scha_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scha00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CP983_18595
Enzymes [BR:
scha01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CP983_18595
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CP983_18595
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QEV68491
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Position
complement(4336467..4338173)
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AA seq
568 aa
AA seq
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MSPTTLPAGLEHGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHEVLDVVRVHARAGI
AEVHTDTGPDADAVPGTGTPQLAVVDGASTTAGLPAVRDAAHLVMEAARGGRRVVRAVSG
DPGLDTYATNEMLACAAAGVPFEVVPGVAAAVGVPAYAGVPLRDAQGADVRFVDARTASD
RCWTEVGASDGTVVVSTTLDSVGAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWTATLGT
IAQTLKQAKVLPSPEGGRPVIAVVGERSAAAQRDQLSWFESKPLFGWRVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHRLAEALADFGLRR
RAAAVEAGDPVTRPSERRPGARRRRSTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacccttcccgccggccttgaacacgggcacgtcaccttcctcggtgcc
ggacccggggatccggggctgctgactctgcgcgccgtcgaggcactggcgaacgcggac
gtactggtcgccgagcacgaggtgctcgacgtcgtacgcgtgcacgccagagccggcatc
gccgaagtgcacacggacacgggtcccgatgcggacgccgtgccgggcacaggcacgcct
caactagcggttgttgacggcgcgtcaacgaccgctgggctacccgcggtgcgggatgcc
gcacatcttgtcatggaggccgcgcgtggcggcaggcgggtcgtgcgtgcggtgtccggg
gatcccggcctcgacacgtacgccaccaacgagatgctcgcgtgcgccgcggccggtgtg
ccgttcgaggtcgtaccgggtgtcgccgcggccgtgggcgtccccgcgtacgccggcgtc
ccgctccgtgacgcgcagggcgcggacgtccggttcgtcgacgcgcgcaccgcgtccgac
cgttgctggaccgaggtcggcgcgtcggacgggaccgtggtcgtgtcgacgacgctggac
tccgtgggcgcggccgccggtgaactggtgtcggcgggacgcaagcccgatacgccgctg
accgtcaccgtcgccggtacgacgacccggcagcggacctggaccgcgacgctgggcacc
atcgcccagacgctgaagcaggccaaggtgctgccctcgccggagggcggccggccggtg
atagccgtggtcggtgagcgttccgccgcagcacagcgcgaccagttgtcgtggttcgag
tccaagccgctcttcgggtggcgggtgctcgtgccgcgtacgaaggagcaggcggcttcg
ctctccgaccagctgcggtcgtacggggccgtgccgcacgaggtgccgacgatcgccgtc
gaaccgccgcgcacgccccagcagatggagcgggccgtcaaggggctcgtgaccggacgg
tacgagtggatcgccttcacctcggtgaacgcggtcaaggccgtgcgggagaagttcgag
gagtacgggctcgacgcccgtgcgttcgccgggatcaaggtcgcggcggtgggggagcag
accgcgaaggcgctcatcgccttcggcgtgaagccggacctggtgccgagcggtgagcag
tcggccgcggggctgctggaggactggccgccgtacgacccggtcttcgacccgatcgac
cgcgtgttcctgccgcgggccgacatcgccacggagaccctggtggccgggctcatcgag
ctcggctgggaggtcgacgacgtcacggcctaccggaccgtgcgggcctcgccgccgccg
gcggagacccgggaggcgatcaaggggggtggcttcgacgccgttctcttcacgtcgtcg
tccacggtgcgcaacctcgtggggatcgccggcaagccgcacaacgtgaccgtgatcgcc
tgtatcggtcccgccaccgcgaagaccgccgaggagcacgggctgcgggtggacgtgatg
gcgccggagccgtccgtgcacaggctggccgaggcgctggcggacttcgggctgcggcgc
cgtgccgccgcggtcgaggccggggacccggtcactcggccgagcgagcggcgtccgggc
gcccgtcggcgtcggtcgacgacgtaa
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