Streptomyces chartreusis: CP983_18745
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Entry
CP983_18745 CDS
T07157
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
scha
Streptomyces chartreusis
Pathway
scha00290
Valine, leucine and isoleucine biosynthesis
scha00770
Pantothenate and CoA biosynthesis
scha01100
Metabolic pathways
scha01110
Biosynthesis of secondary metabolites
scha01210
2-Oxocarboxylic acid metabolism
scha01230
Biosynthesis of amino acids
Module
scha_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
scha_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
scha00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CP983_18745
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
CP983_18745
Enzymes [BR:
scha01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
CP983_18745
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
QEV68514
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Position
complement(4368719..4370572)
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AA seq
617 aa
AA seq
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MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLQPVGRI
VSEAIREAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICI
SNCDKITPGMLNAALRLNIPTVFVSGGPMESGRATLVDGTVRTLDLVDAISDAVNDKISD
EDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARKALYEDAART
VMDITRRYYEQDDDTVLPRNVATFAAFENAMALDIAMGGSTNTILHLLAAAQEAGVPFGL
EQINEVSRRVPCLAKVAPNVAKDRTYYMEDVHRAGGIPALLGELHRAGLLNEDVHAVHSP
SLSDWLKTWDVRGGSPSPKAVELWHAAPGCVRSAEAFSQSERWEALDDDAEGGCIRSAEH
AYSKDGGLAVLKGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQEEAVEKILNKQVTDGD
VVVIRYEGPKGGPGMQEMLYPTSFLKGRGLGKTCALITDGRFSGGTSGLSIGHASPEAAS
GGTIALVENGDRIRIDIPNRSIELLVDETELTRREQALNGVYAPKNRERKVSAALRAYAA
MATSADKGAVRDVTKLG
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagctgaggtcccgcacagtcacccacggccgcaacatggcgggcgcccgcgcc
cttatgcgcgcctccggtgtacccggtgcggacatcggccggaagccgatcatcgcggtg
gcgaactccttcaccgagttcgtgcccggccacacccacctccagcccgtcggccggatc
gtcagcgaggcgatcagggaggccggcggcatcccgcgcgagttcaacaccatcgcggtg
gacgacggcatcgccatgggccacggcggcatgctgtactccctgccgtcccgcgacctg
atcgcggacagcgtggagtacatggtcgaggcgcactgcgccgacgccctgatctgcatc
tccaactgcgacaagatcaccccgggcatgctgaacgccgccctgcggctcaacatcccc
acggtcttcgtctccggcggcccgatggagtccggccgcgccacgctggtcgacggcacg
gtccgcaccctcgacctggtcgacgcgatctccgacgccgtgaacgacaagatctcggac
gaggacatcctccgtatcgaggagaacgcctgtccgacctgcggctcctgttccggcatg
ttcaccgccaactcgatgaactgcctgaccgaggccatcggcctgtccctgcccggcaac
ggctcggtcctcgccacgcacacggcccgcaaggccctgtacgaggacgcggcccgcacg
gtcatggacatcacccgccgctactacgagcaggacgacgacacggtcctgccgcgcaac
gtcgccaccttcgcggcgttcgagaacgccatggccctcgacatcgccatgggcggctcc
accaacacgatcctgcacctgctggccgccgcccaggaggccggcgtcccgttcggactg
gagcagatcaacgaggtcagccgccgggtgccgtgcctggcgaaggtcgcgcccaacgtc
gccaaggaccgcacgtactacatggaggacgtgcaccgcgccggcggcatcccggccctg
ctgggcgagctgcaccgggccggcctgctcaacgaggacgtccacgccgtccacagcccg
tccctctcggactggctgaagacctgggacgtgcgcggcgggtccccctcgccgaaggcc
gtcgagctgtggcacgccgcccccggctgtgtccgctccgccgaggccttctcccagtcc
gagcgctgggaggcgctggacgacgacgccgagggcggctgcatccgcagcgccgagcac
gcctactccaaggacggcggcctcgcggtcctcaagggcaacctcgccgtcgacggctgc
gtcgtgaagaccgcgggcgtcgacgagtccatctggaccttcgagggcccagcggtcgtc
tgcgagtcgcaggaggaggccgtcgagaagatcctcaacaagcaggtgaccgacggcgac
gtcgtcgtcatccgctacgagggtcccaagggcggccccggcatgcaggagatgctctac
ccgacgtcgttcctcaagggccgcggcctcggcaagacctgcgccctgatcaccgacggc
cgcttctccggcggcacctcgggcctgtccatcggccacgcctccccggaggccgcgtcc
ggcggcacgatcgccctcgtcgagaacggcgaccgcatccgcatcgacatcccgaaccgc
tcgatcgagctgctcgtcgacgagacggaactcacccgccgcgagcaggcgttgaacggc
gtgtacgccccgaagaaccgcgagcgcaaggtgtcggcggcactgcgcgcatacgccgcg
atggcgacgagcgcggacaagggcgcggtgcgagacgtgaccaagctgggctga
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