Streptomyces chartreusis: CP983_28510
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Entry
CP983_28510 CDS
T07157
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
scha
Streptomyces chartreusis
Pathway
scha00790
Folate biosynthesis
scha01100
Metabolic pathways
scha01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
scha00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CP983_28510
Enzymes [BR:
scha01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CP983_28510
6.3.2.17 tetrahydrofolate synthase
CP983_28510
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QEV70199
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Position
6485372..6486859
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AA seq
495 aa
AA seq
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MSESDDPFEEIIAAETDRDPDLAVIEAGSRTLRTQGGPPQAHVPARPEDPEVDKALREVE
AELATRWGETKLEPSVSRIAALMDVLGEPQRSYPSIHITGTNGKTSTARMIEALLGAFEL
RTGRYTSPHVQSVTERISLDGAPVSAERFIETYNDIKPYVEMVDSSQEYRLSFFEVLTGM
AYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLGSTPGEIAVEKAG
IVKQDATVIMAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVARQVAVGGQQVTLRGLGG
EYPEVYLPLHGAHQAHNAAVALAAVEAFFGVGAARAEPLDIDTVRKAFASVSSPGRMEVV
RRSPTVVLDAAHNPAGARAAAEAIGEAFDFSRLIGVVGASSDKNVRELLEAFEPIFAEVV
VTQNSSHRAMDADELAAVAVEVFGDERVQVEPRLPDALEAAITLAEEEGEFTGGGVLVTG
SVITVGEARLLLGKG
NT seq
1488 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagagcgacgaccccttcgaagagatcatcgcggcggagaccgaccgcgacccc
gatctcgccgtcatcgaggccggcagccgaaccctgcgcacccagggcggcccgccgcag
gcgcacgtgccggcgcgccccgaggaccccgaggtcgacaaggcattgcgcgaggtcgag
gcggagctcgccacccgctggggcgagaccaagctggagccgtcggtcagccgtatcgcc
gcgctcatggacgtcctcggcgagccccagcgctcgtacccctcgatccacatcaccggc
accaacggcaagacgtcgaccgcccgcatgatcgaggccctcctcggcgccttcgagctg
cgcaccggccgctacacctcgccgcacgtccagtcggtcaccgagcggatcagcctcgac
ggcgccccggtctccgccgagcgcttcatcgagacgtacaacgacatcaagccgtacgtc
gagatggtcgactcctcgcaggagtaccgcctgtccttcttcgaggtgctcacgggcatg
gcgtacgcggccttcgcggacgcgcccgtcgacgtcgccgtcgtggaagtgggcatgggc
ggctcctgggacgccaccaacgtcatcgacggtgatgtcgccgtcgtgacgcccatagac
ctcgaccacaccgaccggctgggctccaccccgggcgagatcgccgtcgagaaggccggc
atcgtcaagcaggacgccaccgtgatcatggcccagcagccggtggacgccgcccaggtg
ctgctgaagaaggccgtggaggtcgacgccaccgtcgcccgcgagggcctggagttcggg
gtcgtcgcacgtcaggtcgccgtcggcggacagcaggtcacgctgcgcgggctcggcggc
gagtaccccgaggtgtacctgccgctgcacggcgcgcaccaggcgcacaacgccgccgtc
gccctggccgcagtggaggcattcttcggcgtcggcgccgcacgcgccgagccgctggac
atcgacacggtccgcaaggccttcgcgtccgtctcctcgccgggccggatggaggtcgta
cggcgctctccgaccgtcgtgctggacgccgcccacaacccggcgggcgcgcgggcggcc
gccgaggcgatcggggaggccttcgacttcagccggctcatcggcgtggtcggcgcgagc
agcgacaagaacgtgcgggagctgctggaggccttcgagccgatcttcgccgaggtcgtc
gtcacacagaactcctcgcaccgcgcgatggacgccgacgaactcgcggccgtcgccgtc
gaggtgttcggcgacgagcgcgtgcaggtcgagccgcggctgccggacgccctggaggcc
gcgatcacgctggccgaggaggaaggcgagttcacgggcggcggtgtgctggtcaccggg
tccgtcatcacggtcggcgaggcccggctgctgctggggaagggctga
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