Streptomyces chromofuscus: IPT68_20660
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Entry
IPT68_20660 CDS
T07378
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
schf
Streptomyces chromofuscus
Pathway
schf00860
Porphyrin metabolism
schf01100
Metabolic pathways
schf01110
Biosynthesis of secondary metabolites
schf01120
Microbial metabolism in diverse environments
schf01240
Biosynthesis of cofactors
Module
schf_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
schf_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
schf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
IPT68_20660
Enzymes [BR:
schf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
IPT68_20660
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
IPT68_20660
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QOV42253
UniProt:
A0A7M2T323
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Position
4585375..4587084
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AA seq
569 aa
AA seq
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MSPTTLPAASPEHGHVTFLGAGPGDPGLLTLRAVEALAHADVLVAEHEVLDVVRTHARPG
VAVVNTDPGPSSDLGPGTGTPQLTVVDGTSATVGVPAVRDAAHLVMEAARGGRRVVRAVS
GDPGLDAYAAEEMLACAAAGVPFEVVPGVAAAVGVPAYAGVPLRDAQGADVRFVDARTAS
DRCWTEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPMTVTVAGTTTRQRTWTATLG
TVAQTLKQAKVLPSPEGGRPVIAVVGERSAAARREQLSWFESKPLFGWKVLVPRTKEQAA
SLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKF
EEYGLDARAFAGIKVAAVGEQTAKALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPI
DRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTS
SSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGMK
RRAAALEAGDPVTRPSERRPGARRRRTTT
NT seq
1710 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacccttcccgccgccagtccggaacacgggcacgtcaccttcctgggt
gccggacccggggatccgggactgctgactctgcgcgccgtcgaggcgctggcgcacgcg
gacgtactcgtcgccgagcacgaggtgctcgacgtggtacgcacgcacgccaggccgggc
gtcgccgtcgtgaacacggacccgggtccttcttcggacctcggtccgggcacaggcacg
cctcagctgacggttgttgacggcacgtcagcaaccgttggggtccccgcagtgagggat
gccgcacatcttgtcatggaggctgcgcgaggcggcaggcgggtcgtccgtgcggtgtcc
ggggacccggggctcgacgcgtacgccgccgaggagatgctcgcctgcgccgcggcgggt
gttccgttcgaggtggtgcccggtgtcgcggccgcggtcggggtgccggcgtacgccggt
gtgccgctgcgggacgcgcagggggccgacgtgcggttcgtggacgcgcggacggcttcc
gaccggtgctggacggaggtcggggcgtcggacgggacggtcgtcgtgtcgaccaccctc
gactccgtggccgcggctgccggcgagctggtgtccgcggggcgcaagcccgatacgccg
atgaccgtgacggtcgcggggacgacgacccggcagcggacgtggaccgcgacgctgggg
accgtcgcgcagacgctgaagcaggcgaaggtgctgccgtcgcccgagggcgggcggccc
gtgatagccgtggtcggggagcgttccgccgccgctcggcgtgagcagttgtcgtggttc
gagtccaagccgctgttcggctggaaggtgctcgtgccgcggaccaaggagcaggcggct
tcgctttccgaccagctgcggtcgtacggggccgtgccgcacgaggtgccgacgatcgcc
gtcgagccgccgcggacgcctcagcagatggagcgggcggtcaaggggctggtcaccggg
cggtacgagtggatcgccttcacctcggtgaacgccgtcaaggccgtgcgggagaagttc
gaggagtacgggctggacgcgcgggccttcgcggggatcaaggtggccgcggtgggggag
cagacggcgaaggcgctggtcgccttcggcgtgaagccggatctggtgccgagcggggag
cagtccgcggcggggttgctggaggactggccgccgtacgacccggtgttcgacccgatc
gaccgggtgttcctgccgcgggccgacatcgccacggagacgctggtcgccgggctgatc
gagctcgggtgggaggtggacgacgtcacggcctaccggaccgtgcgcgcgtcgccgccg
cccgcggagacccgggaggcgatcaagggcggtgggttcgacgccgtgctgttcacgtcg
tcgtccacggtgcggaatctggtcggtatcgccggcaagccgcacaacgtgaccgtgatc
gcgtgtatcgggcccgccacggcgaagaccgccgaggagcatgggctgcgggtggacgtg
atggctccggagccgtccgtacacaagctggcggaggcgctggccgacttcgggatgaag
cggcgggcggcggcgctggaggccggggatccggtgacgcggcccagcgagcggcggccg
ggggctcggcgtcggcgcacgacgacgtag
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