Schlesneria sp. DSM 10557: QJS52_08080
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Entry
QJS52_08080 CDS
T10918
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
schl Schlesneria sp. DSM 10557
Pathway
schl00300
Lysine biosynthesis
schl00550
Peptidoglycan biosynthesis
schl01100
Metabolic pathways
schl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
schl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
QJS52_08080 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
QJS52_08080 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
QJS52_08080 (murF)
Enzymes [BR:
schl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
QJS52_08080 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
XFP05477
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Position
6162984..6164399
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AA seq
471 aa
AA seq
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MQRFSLRDLTRATGGRLRDVSNIDACFDRVFIDSREVQPGSIFWALKGEHLDGHHFTGEA
HQRGAHLSVVAAESASAVSGAVLIVDNPLTALGRFAAWHRHRLDPLVIGITGSVGKTTTR
ELTYAALGCQFQGIRSRKNYNNLIGLPLSLLELNSSHEFAVIEMGASRVGDIRELCDIAC
PEIGIVTAVGPAHLESFGSLAAVFQAKGELLEQLPTTGFAVLPGDDPDLRQMADRAPCPV
IFVGQGDDNHIQATQIEPRPGNLRFHCEGTRFDVPVNGRHAVSNALCAIGVGLEIGIPIE
QLASGLARFSPPPGRGGLQKIGPWTVLDDTYNASPLSVAAACHALNELAIPGVQKRMLVL
GDMRELGSTSKMEHERIGRLAAQLQIDRILVCGEFADDVARGAIQSGMNPEQVAAATHVE
SLLAVLNRWLEPNDILLVKGSRSTRMERVIEWLNSCAEFAFTAERQQKACA
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
atgcagcggtttagcctccgagacctgacacgggcaacaggcggtcggcttcgggacgtc
agtaacattgacgcttgtttcgaccgagtcttcatcgactcacgcgaagtccagccagga
agtatcttctgggcactcaagggggaacatcttgacgggcatcacttcaccggtgaagct
caccagcgcggtgctcacctgtccgtagtcgctgccgaatctgcatcggctgtctctggg
gccgttctgatcgtggataatccactgaccgcattaggtcggttcgccgcatggcatcgc
catcgactggacccgctggtcatcggcatcactggaagcgtaggaaaaacgacaacgcgt
gagctgacttacgcggccctgggctgtcagtttcaagggatccgcagccgcaaaaactac
aataacctgatcggactgccgctcagcctgctcgagctgaattcgtcgcacgaatttgcc
gtcatagaaatgggtgcctcacgcgtgggggatatccgcgaactttgcgatattgcctgc
cccgaaattggtattgtcaccgcagtgggcccagcccacctcgagtcttttggctcactt
gccgcagtctttcaggccaaaggagagttacttgagcaactgccgacgactggctttgcc
gtacttccgggagatgatcccgatctgcgccaaatggctgatcgggcaccgtgtcctgtc
atttttgtcggccagggtgatgacaatcacatccaggccactcaaatcgaaccccgtccc
ggcaatttgcgtttccactgcgaaggaacccgatttgacgttcccgtcaacgggcgacac
gcggtctccaatgcactttgcgcgatcggagtcggtcttgaaatcggcatcccgatcgag
cagctcgcgagcggtctcgcccggttttcaccccctccaggacgtggcggacttcagaaa
attggtccgtggacggtgcttgacgacacgtataacgccagtccgctttccgtcgccgcc
gcgtgccacgcgttaaatgaactggcgattcccggtgttcagaaacggatgctggtgctg
ggcgacatgcgagagctcggctcgacctcgaaaatggaacacgaacgaattggccgcctg
gcggctcagttgcagattgatcgaatactggtctgtggtgagtttgcagacgatgttgcg
cggggagcgatccagtcagggatgaaccccgaacaggttgcggcggcgacccatgtcgaa
agccttttggcagtcctgaaccgctggctggaacctaacgacatcctgctggtgaaagga
tcgcgatcaacgcgaatggaacgagtcatcgagtggctgaactcatgtgcagaatttgca
ttcactgccgaacgacaacaaaaagcctgcgcctga
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