Candidatus Sumerlaea chitinivorans: BRCON_1608
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Entry
BRCON_1608 CDS
T09023
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
schv
Candidatus Sumerlaea chitinivorans
Pathway
schv00300
Lysine biosynthesis
schv00550
Peptidoglycan biosynthesis
schv01100
Metabolic pathways
schv01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
schv00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BRCON_1608
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BRCON_1608
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BRCON_1608
Enzymes [BR:
schv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BRCON_1608
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AXA36385
UniProt:
A0A2Z4Y7J4
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Position
complement(1843160..1844545)
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AA seq
461 aa
AA seq
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MNISFTELAQFLGISSPSGNPEGKIATISTDTRTIQPGDCFVALRGVSFDGHNFVPQAVA
GGAAALVAERYFPEFAHVPQFVVPNTLWALGEIARLWRNKLAHIPLVAVVGSNGKTTVKE
MTANILATRYRTLSTQGNLNNLVGVPLTLFRLEPTHEAAVLELGMNQAGELERLVQITSP
NVLVLTNITNAHVGMFGSLEGLYAAKTESLRAAPPTCKFVLNAEDELSQRATAEFAGNHP
VVRFGVCPEADVRAECIEPLVPFGYRFVLVLPSGESTPVELRMFGRHNVANALAAAAVGA
LCGVTPQKIAEALASFQPASNRSEVEELNGWYLVKDYYNASPAAVEQALRSLAEFSVPGR
RYAVLGDMMELGDLEEYYHTRVGETAAQSGLERLFTIGTRARTIHAAASRHGLPSEHFEE
IDDLAKALKMQLRAGDLLLMKASRLMKLERLYDLLKGTKSN
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgaatatttcgtttacagaattggcgcaattccttggcatctcttcgccttctggcaac
cccgagggtaagatagccacaatttccacggatacacgcaccatccaacccggcgactgt
tttgtggcgcttcgaggagtctctttcgatggccacaacttcgtcccccaagcagttgcg
ggaggggctgcagcgctggtggccgagcggtactttcctgaattcgcgcacgtgccccag
tttgttgtcccaaacacgctttgggcgttgggcgaaattgcacgactgtggcgcaacaaa
cttgcccacattcctctcgtagccgtcgttggctccaatggcaaaacgacggtgaaagaa
atgacggccaacattctcgcgacgcgttatcgtacgctctcgacgcagggcaacctcaac
aatcttgtgggcgttcccctcactcttttccggttggaacccacgcacgaggccgccgtg
ctcgagcttggcatgaaccaagccggagagctggagcgtctcgtgcaaatcacgagcccc
aatgtgctggtgctcacaaatatcacgaacgctcacgtggggatgtttggatccctcgaa
ggtctgtatgcggcgaaaaccgagagtttgcgtgctgctccgccgacgtgcaaatttgtg
ctcaatgctgaggatgaactctcgcagcgggcgacagcggaatttgcggggaatcatcca
gtggtccgctttggagtgtgccctgaagccgacgtccgggctgaatgcattgagcccctt
gttcccttcggctatcggttcgtgctcgtgttgccatctggggaaagcacgcccgtcgag
ctccggatgttcggtcgccacaacgttgccaatgccttagcggctgctgctgtcggagcg
ctttgtggtgtgaccccgcagaagatcgccgaagcacttgcgagcttccagccggcatcc
aatcgcagcgaggtcgaggagctcaacggctggtaccttgtgaaggattactacaatgcc
agtcctgccgcggtggaacaggcactgcgctcactggcggaattttcggttccgggccgg
cgctatgcagtgctgggcgacatgatggagctcggcgatttggaagaatactatcacacg
cgagtaggggagaccgctgcgcaaagcgggcttgaacggctgttcaccatcggtacgcgg
gcgcgcacgattcatgccgctgccagtcgtcacggtttgccatctgagcattttgaggaa
atcgacgaccttgcaaaggcactgaaaatgcagttgcgagccggagatttgctgctcatg
aaagcctctcggctcatgaaacttgaacggctctatgacttactgaaagggacgaaatcg
aactga
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