Streptomyces collinus: B446_33610 Help Entry B446_33610        CDS       T02787                                  Symbol kirAIV Name (GenBank) modular polyketide synthase Organism sci  Streptomyces collinus SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ketoacyl-synt Ketoacyl-synt_C KR PP-binding KAsynt_C_assoc RhiE-like_linker CurL-like_PKS_C PS-DH adh_short Thiolase_N PKS_DH_N adh_short_C2 Methyltransf_12 ACP_SdgA_C Methyltransf_23 Epimerase Methyltransf_25 Methyltransf_11 GDP_Man_Dehyd Methyltransf_31 Beta-ketacyl_N Ubie_methyltran Methyltransf_33 Methyltransf_28 Motif Other DBs NCBI-ProteinID:  AGS73526 UniProt:  S5V790 LinkDB All DBs Position 7807634..7826830 Genome browser AA seq 6398 aa AA seqDB search MGNSTEDRAARLVVLSAGGRDQLDRYRAELVGWLQAHPEAALDRIESTLRTGREELAERL AVVVTGVAELTERLRDGTGVVTGTAGPATGEPVQAADLHEAARLWVTGTPVRWPEQASGR SARLSLPQPQPVTRRYWIEPPAALTADPAERLLTGDEFFLRDHALGQVRVLPAVAALEFA VDTAARAGHGRATGVDHVLWARPVLFTGEPVRVRLRFAPAADGVAYELRRLDDTPDGELC STGTLRFGPTEPAPSLDLAAIRARLPRTTSADDCYAVFAALGGGYGPSLRGLRSMRSVPG EALAEVAVPDAADLPFDDFTLHPSLLDAMLQAALWTAADPSAPRPRELPFSIDRVEILGP LPEHGYAHAVATGTGHDIALADADGRIAVRLRGVVTRSVKDPADPVDTHLLAQRWQDAPV RRGAPATGRKVILEAGEDGCLPDSGPLVVVRLGDDDPLPSLVRLFRTWAAQPNRQPLRVL HVFRPSGAVTDARLLALDGMARSIANEHPDFRAAVITTDGADPRAVADAEAAADHEFRVR YTAAGRQVARWEPIAPAPAPLTPEGTVLVTGGAGALGRHLVSHLGPSARYVLTGRSADAD LTDLRATGLDVHYLPCDLGAPGAAERLVERVHQRFGPLRGVLHLAGVTRDSFLLRKTDED IAAVLGPKVDGTLALDRATAADPLDFFVCFSSMSGAGSPGQADYAYANRFLDAFAAWRRG SDRPGRSLSVLWSLWADGGIRMDADDTTQARIARRAGLRPLPTADALRAWDRALGHDGDH VLVAHGELDRIRALLDAPAPEPAPAPEPAPRAATGSATAAAEEFLRGVLAEVLQYPQEEI EADTAFEQYGIDSLLIMDLTRRLEDHFGSLPKTLFFEYQELRGLAGWFAEHHGGRLAELT PAPAPVPVPVQAPVVVATPDAAPSGERPAPPSADAPEPVAIIGVAARFAESDTLDEFWAN LRAGRDLITEIPADRWDWRDYDEATPADRAAEYSRWGSFLRGIDRFDPLFFGISPREAEI IDPQERLFLQTAWHAMEDAGLTRADLRARRVGVYAGAMYGLYQLHEAADGRIGASSHASI ANRVSYTLGVTGPSLGVDTMCSSSLTAIHLAVRDLRSGEAEMALAGGVNLHVHPYKYQFL GQGTFTSSDGRCRSFGADGDGYVPGEGVGAVLLKPLSAAVRDGDHIHGVILGSSVNHGGR TNGFTVPNPVAQSDLVERALAEAGCSAAALGYLEAHGTGTALGDPVEVRALARALGASGL PRGSLPIGSVKSNIGHLESASGMAGLCKVLLQMRHGELVPSLHADPVNPNIDFASTPLRV QTETAPWPRRDGLPRRAGISSFGAGGANAHLVVEEYVPGPAPAAAPGPWLFPLSARTPEG LRALAERLADAVDNGLADRLADVAYTLQHGREAWADRMVVLASTADELAGRLRAGTGTGV WTGSVRGRAASRAAAPAAADPAGLAAAWTSGATVAWPGTGRRLPLPGYPFEELRCWLTER MWAPSPAGPATHPLLDEIVPADSVDGLTFRTAFAPAHPLIDGHRVGDLRLLPAAAVLEMA RAAAAHAGYPVPVRLRDVRWLRPLVVTGTVASARTRLRRDGAGLAFTLLGDTGDQLAQGL VEARADDVPEPVPVERIRAALPHRHDGADLYTDLAGAGLVYGPALRAVEWIASGTDEALA SLRVPAEAARFADCALPPALIDGALHTFAVLRDRAGGPMVPFALAAAEVVGPLPEHVYAH VRTVGPDRYDLTLTDPDGGVLVLLRDLCLRPAPAAGTSDAGPAVTAVTAGPAVTERPVDD LMYLPRWSPVAAEPFTVPSTAPGSDTWLIRPSCAAPLAAALATRLGGSVTEIEPEHFVAP AGRPGHVIVLSGPAQGRTDDPAALDLAQERGVLALFRAAKALQRSGAPVRLTVVTEDALS TGTEPVRNPYAASLHGLALSLAQEQPRWRVAVVDRSSADPISPDVLDVPAGGPYALRAGV LHRRSLVPAAPTTTREAIRHGGVYLILGGAGGLGLELTEWLVRGYRAKVVLVGRSELDAG RRDRLRRLDPAGALVSYRRADATDPAALAEVVTAVRAEHGTLHGVVHATIVLRDQTVATM TEDTFRAVLDAKTRTSVALHRALVAADGLDFVLFFSSAVALSGSAGQANYAAGSTFEDAF AHHLDDVLAARSAVVNWGYWGTVGIVADDRHRERLARTGIHSITPAEGMAAVHDVLGRTD RQVVVIKATAEVLAAAGVERPAGERSDDELAPSAAALPPVARLLTETDQARLDEVVLGWL WELFRGEGVFRTVGERWSADELRRRLRIADGQSRLFAELLRVLTVAGFLRDDGSALIATD RRAPTDPENELVVLCEGQPALNRIDRLLRPCMHQLFGVLRGTVRATEVMFPGGSTELVEG AYRGSPVVDRANELVVAAVLDRVGRLGGPVTVVEVGAGTGGTTASLLPALAATGVELTYV YTDISPAFLQHGRQRFAERYPMVRFQQLDISGDPLAQGFPPGGADVVVAANVLHATPDLP HTLRAVALLLKSGGHLVLNEATSNVVTATLTFGLLDGWWLHRDTGLRLPGSPLLSGRGWR AALDLAGFTRSRALPADEGLTQHVVVAESGPAGPAAVTAPTAQPAPPPAAEPAPEPRTGG GGRLVEAARDYVKDAFVQVLEVPRDRLWLDETYENFGVDSLTVPRIADLLAERMGDLPPT LLFEHPTIREVADHLVERYPDRVRALLPDQPRPAPAQATEPAPAQATEPAPAQVTEPAPA QVTEPAGRPAKTAPAADTRIAVIGVAGRYPLADDVDAFWTNLRTGLDCIREVPAERWDPR TEPGANGTPVSRWGGFLDRIDEFDPRFFQMSMHEAELTDPQERLFLQTAWHTLEDAGYPR TRLRGSRVGVYVGVMYGHYQLFEDERGLAGGMGYASIANRVSYALDLHGPSLAVDTMCSS SLTAIHLACEALAAGGVDYALAGGVNLTPHPRKYRQLAAGGFTGESGRCRSFAAGGDGMV PGEGVGAVLLKPLAAAERDGDRILGVILGSAVNHGGKTGGYAVPSPGAQSEVVTSALRAA GVEPADVSYVEAHGTGTALGDPAEVAGLARAFGDRPAGSIAIGSVKSSIGHLESAAGIAA LTKVLLQMRAGELTPSLHAEQLNPAVDWANVPFRVQREAAPWTGPRPLRAGVSAFGAGGS NAHLVVEQYRAEPRPGVVPMPAVFPFSGRDAQALRRIVERMLSRLRELGATGLRGEPGAT GLAEIAAAAGLPVGAVDEPLDELGLDPATIMRLAGRETALHQGAVHSGSTLRQLAAAPPD AADIDLGRLSYTLQIGREAMAHRLAVVAHRTDELIEQLDAFLAGRPAGWTGVVTTEPGDP VAPSADPRDNARRWVQGEVIDWAGTAGSAPEPLPLPGYPFEPVRCWIRSAAPRAATPTPT RPAGSSGPALTTVLRLVSGVTGYPMTELDPAASFHDHGLDSLALLRLAGDVSAAFDLPVG PDQLLATPTAAALADWLAREHPQGAPARPAEPEPDDPVVIVGMAGTLPGSADLDEFWAAL ERGGDLFTEVPADRWDAREHHGDPAAHPERTRVTRAGFIGGIDRFDPLFFGISPREARWM DPRQRLLMRTVWAALEDAGMDPGALAGSDTGLFVGVGSGEYAELVQRSGAATDAYSSTGL APSMLANRISYQLDLHGPSEPVDTACSSSLVALHRAAEALRLGRCGTVIVGGVSLMLSPV TFASLERAGMLSEDGVGRAFDADASGYVRGEGVGAVVLKRLSRARADGNPILAVLRGTAV NHGGRANSLTAPSPRAQADVIRRAHREAAVDPATIGYLETHGTGTVIGDPAETNGLREAF ADLYQDWGHDAPARPHCALGALKNTIGHLEPAAGIAAVLRVLLSMRHGRITGDPHGPRPN PHLGLEGTPFELATGPREWAPPAPGVPRRAGVSAFGYGGANAHVVLEEYPAEEPVPAPGP VVFVLSARDPERLRAYARSFADRPDRWAHDLASTAYTLQVGRGAYPERLAFVTDSAEHAV ATLRRFLAGDTAGIHTGRVERDADRTPCDGRGDDETAAAWTRGAQVDWHRRWAAPPRRRS LPTYPFAQERHWFTDGTTARPVSCFTATWQDEPVPAAGEHPGRVLVLGDLPVPGAVHVRA GTEYRDEGPVITIRPGEQDDYARLLAETPARIVHQWPLLAPGRDDLGLEAMFRIAKELTA GAARTPVRIQALVPEDALAEAWGGFDASLRAALPGTTFGVVRVDGAGDTGELLAEIAAHR LSGPAVRLSPSGRSVRVLSEIPARPVLPSPLRDGGVYLITGGLGGLGVLLARTLLSRGAR VALTGRSPAAERAEQLAELRAHGTVAYYRAAVEDRDAMTRVVAEVIADLGGLDGLFHLAG TASRNPLPGKDVDELRAHLRARITGTRVLDEVTRDLPLDLFVLYSSLAGQLGDYGLVDYA VGARYLDGFADFRERERLAGRRHGRTVSVDWPMWRAGGMHVDTDDERRYLAGTGFRYLET AEGEQVLDLVLRLDRPQVAVLPGDPARMRDLVAGMRLRDDGVPALPAPPPTPAPAVAVSP ELPTQLRELIGGILGIAPSALDPDAGFGEYGLDSFGLQNLAAALAARYDVTVPTTTLFGA NTVTKLAAHLAAELPPAPVAKRTEPGPASSEPGPASSESAPAPVSVPHGVPAPAPVSVPH GVPAPASGSSSAAPAGHEPIAIIGLAGRLPGADDLEQFWQHLADGRDLITETPADRWDWR EVARRFGGTARWGGFLTGVDLFDPLFFRISPAEAQAMDPQHRLFLEHTWGALEDAGCRPD RLAGGRVCVFAGVQFADYESMVLRGEHVNAHAGTGLARTMLANRISYLLDLRGPSESVDT ACSSSLVALHRAVRSLRAGESDLAIAGGVSLVLSPQTVVAGNQLGVLAPDGRCKALDESA DGYVKGEGVGVVVLKTLSRALADGDRVHAVIRGSAVNHGGRASSLTSPNPLAQADLLVEA YGDADVPIETVSYVELHGTGTALGDPVEIDGLVRAHRALAAGPPVTCGIGTVKSNIGHLE PAAGIAGVIKVVLAMRHRQLPPTLHLSRLNPLIDLDGTPFEPVRETRPWTPSDADGTTVP LRAGVSSFGFGGVNAHVVLEEPPVTSVPVDSTGPEIFVLSARDEAALHRYARAHLAFLGD RQPALSSLAHTSQVGRVPMPVRLALVVRSVAELRDRLAAFLAGDIEATTATGDHDWLTEP EGVSYLRRLAREGRLDRIARLWQAGAAVDWAALRTDRPALTSMPTYPFARERHWLASPSA APPEHEARRLLAKEWEPAPAASGPAPTAPVVLVRAETEALATAAFGDTARVVRLDDTDEE TGLRAAASIGRAPVVIDLVDLSAVPVPDVRVDWARIVLARELIATNRTAGFAYLHLTRGL VSFRAHSPTLRGAAFAGLVRMLSAEYRGVFARTVDVDFTDPDALRDVAGAELAATDPVTE VCVRDGVRYTPTLRPTGCATAPARWSDDLAGRPVVITGGTGALGRLLAAELVERGANRLV LLGQSPLPARDNWAELMAAPDTDPALAARLRDLSALERAGVRLVIESIPLERAREVLDRI RREWGPIAGIVHCAGLGVMTDPAFIGKRTADMRRVVEPKTTGLQALLDACGDDPLRFVVL YSSIAGQVPALAAGMSDYALANSVLDRVAEYRNATGADTPVFRSVQWPSWQAAGMPEVDT PVYRELGLRTLRPQDGVALLDAALAGPDPVVLPCLVDTTRFDARALLEVAVPGSSVPGTS APGTPVPGASGPGTSAPGTPAPRASGPGTSALETTDPGTSVPGHPAPGALAPVAAADPPT AHGRRTGDGVRRLTEVFATTLRLDAAQIRPDADFADLGVDSIMIVQLLAALERDLGVVAE PSALLENPTIARLAAALDDRLPEQPAPGKPEPVRAPQPRPAQVRGPERGIAVVGIAAHFP GAPDHATFWRNLVGGVDSVTEVPPSRWDADRFWHPAPQPGRTVSKWGGFLDGIEDFDPDY FRLDPAGAAHVDPLVRQFLEAGAECLADAGLTPAEVAGRRVGVFAGARAANFGAHHAAAT THSISGMAQNFIAAHLSHYLDVRGPAVVVDSACSSALVAVHLAAQSLRTGESDLVIAGGV EILLDEVPFVGMSGAGALSPSGRCHTFDERADGIVLGEGVGALLLKRAEDAIRDGDRVYA VIEGSAVNNDGRTMGITTPNPRAQREVVESALAAAEVSPVQLGYVEAHGTGTMIGDPMEL KALTEVLRGATDEVGFCGVGSVKTNIGHTLSAAGIAGLIKVVLSVHHGQLPPTLHCATLN RRFEFDRSPLFPVRELRDWTGRDGVRRAGVSSFGFGGTNAHMVVRQAPDGHVPLREPLDP PRYRRRRFWFDVPVPASAGANGRHDGPTPPAPFFQIQF NT seq 19197 nt NT seq  +upstreamnt  +downstreamnt atgggtaacagcaccgaggaccgtgccgcccggctggtcgtcctgtcggcgggcggccgc gaccagctcgaccggtaccgtgccgagctggtcggctggctgcaggcgcacccggaggcg gcactcgaccgcatcgagagcaccctgcgcaccggtcgcgaggaactggccgaacgactc gccgtggtcgtgaccggcgtcgccgagctgaccgagcggctgcgcgacggcaccggggtg gtcaccggcaccgccgggccggccaccggcgagcccgtccaggccgcggatctccacgag gccgcccgactctgggtcacgggcaccccggtccgctggccggagcaggcgagcgggcgc tcggcccggctgtcactgccgcagccgcagccggtgacccgccggtactggatcgaaccg cccgccgccctcaccgccgatccggccgagcggctgctcaccggcgacgagttcttcctg cgtgaccacgcgctggggcaggtgcgcgtcctgcccgccgtcgcggccctggagttcgcc gtcgacaccgccgcccgcgccgggcacgggcgcgccaccggcgtcgaccacgtcctctgg gcccggccggtcctgttcaccggcgaaccggtccgggtacggctgcggttcgcgccggcc gccgacggtgtcgcctacgagctgcggcgcctcgacgacaccccggacggtgagctgtgc tcgaccggaaccctgcggttcggccccaccgagccggccccgtccctcgacctggccgcg atacgcgcccgtctgccacggacgacctcggcggacgactgctacgcggtcttcgccgcg ctcggcggcgggtacgggcccagcctgcgcggactgcggtccatgcgttccgtccccggc gaggcgctggccgaggtcgccgtccccgacgccgcggacctgccgttcgacgacttcacc ctgcacccgtccctgctggacgccatgctgcaggcggcgctctggaccgccgccgacccg tccgcgcccaggccccgcgaactgcccttctccatcgaccgggtggagatcctcggcccg ctgccggaacacgggtacgcccatgccgtcgccaccgggaccggccacgacatcgcactc gccgacgccgacggccgcatcgccgtccgtctgcgcggcgtggtcacccgctccgtcaag gatccggccgacccggtggacacccacctgctggcgcagcgctggcaggacgcccccgtc cgccgcggcgcccccgccaccggccgcaaggtgatcctggaagccggtgaggacgggtgc ttaccggactccggcccactcgtggtggtccgcctcggtgacgacgacccgctgcccagc ctggtccggctcttccggacctgggccgcgcagccgaaccggcagcccctccgcgtgctg cacgtcttccgcccgtccggcgccgtcaccgacgcccgcctgctggctctggacggcatg gcgcgcagcatcgccaacgagcacccggacttccgtgccgcagtgatcacgaccgacggc gccgacccgcgagcggtcgcggacgccgaggccgcggcggaccacgagttccgggtccga tacaccgccgccggccggcaggtggcccgatgggagccgatcgcccccgcgccggcgccg ttgacgccggaggggacggtgctggtcaccggcggcgccggcgcgctcggccgacacctc gtcagccacctgggcccgtcggcccggtacgtgctcaccggccgttccgccgacgccgac ctgaccgacctgcgcgccaccgggctcgacgtccactacctgccctgcgacctgggtgca cccggcgcggccgagcggctggtcgagcgcgtccaccagaggttcggcccgttgcgcggg gtgctgcacctggccggggtcacccgtgactcgttcctgctgcgcaagaccgacgaggac atcgccgcggtgctggggccgaaggtcgacggcacgctcgcactggaccgggccacggcc gcggacccgctcgacttcttcgtctgcttctcctcgatgtccggcgcgggcagcccgggc caggccgactacgcgtacgcgaaccgtttcctcgacgcgttcgcggcctggcggcgcggc agcgaccgccccggccgcagcctcagcgtgctgtggtcgctgtgggccgacggcggcatc cggatggacgccgacgacaccacacaggcccgcatcgcccgccgcgccggactccggccg ctgccgaccgcggacgccctgcgcgcctgggaccgggcgctgggccacgacggcgatcac gtgctcgtggcgcacggtgagctggatcgcatccgcgccctgctcgacgcgccggcgccg gaaccggcccccgcaccggaaccggcgccgagggccgccaccgggtcggccaccgcggcc gccgaggagttcctgcgcggcgtgctggccgaggtcctccagtacccgcaggaggagatc gaggcggacaccgcgttcgagcagtacggcatcgactcgctgttgatcatggatctgacc cggcggctcgaggaccacttcggatcactgccgaagaccctcttcttcgaataccaggaa ctgcgcgggctcgccggctggttcgccgagcaccacggcggccgcctcgccgaactcaca ccggcaccggctccggtgccggtgccggtgcaggcgccggtcgtggtggccacaccggat gccgccccgagcggcgagcgtcccgcgccgccctccgcggacgccccggaacccgtcgcg atcatcggcgtcgcggcccggttcgccgaatccgacaccctcgacgagttctgggcgaac ctgcgagccggccgtgacctgatcaccgagattccggcggaccgctgggactggcgcgac tacgacgaggccaccccggcggaccgcgccgccgagtacagccggtggggcagctttctg cgcggtatcgaccggttcgacccgctcttcttcggcatctccccccgagaggcggagatc atcgaccctcaggagcggctgttcctgcagaccgcctggcacgccatggaggacgccggc ctcacccgggccgacctgcgcgcccgccgcgtcggtgtgtacgccggcgccatgtacggc ctgtaccagctccacgaggccgccgacggccgaatcggcgcgtcgtcgcacgcgtccatc gccaaccgggtctcgtacaccctgggcgtgaccggccccagcctgggtgtggacaccatg tgctcctcgtcgctgacggccatccacctcgccgtgcgcgacctgcggtccggcgaggcc gaaatggccctcgccgggggtgtcaacctgcacgtccacccgtacaagtaccagttcctc ggccagggcaccttcacctccagcgacggccgttgccgcagcttcggcgcggacggcgac ggctacgtgcccggcgagggcgtcggcgcggtgctgctcaagcccctgtcggccgccgtc cgcgacggcgaccacatccacggcgtcatcctgggcagctccgtcaaccacggcggcagg accaacggcttcaccgtgcccaacccggtcgcccagagcgacctcgtcgagcgtgccctg gccgaggccgggtgctccgccgccgcactcggctacctggaggcacacggcaccggcacc gcactgggcgacccggtggaggtccgggccctggcccgcgcgctgggcgcctccggcctg ccccggggcagcctgccgatcggctcggtgaaatccaacataggccacctcgaatcggcc tccggcatggccgggctctgcaaggtgctcctgcagatgcggcacggggaactggtgccg tcgctgcatgccgacccggtcaatccgaacatcgacttcgcctccacgccactgcgggtg cagaccgagacggccccgtggccgcgccgggacggcctgccgcgccgcgcggggatcagt tcgttcggcgcgggcggagccaacgcccatctggtcgtcgaggagtacgttcccgggccg gcgccggctgccgcaccgggcccctggctcttcccgctctccgcccgcaccccggagggc ctgcgcgcgctggccgagcggctggccgacgcggtggacaacggcctcgccgaccggctc gccgacgtggcgtacacgctgcagcacggccgcgaggcctgggccgaccgcatggtggtg ctcgcctccacggcggacgagctggccggtcggctgcgcgcgggcaccggaaccggcgtg tggacgggcagcgtccgcggccgtgccgcctcccgcgccgccgcgccggccgccgcggac ccggccggcctggctgccgcctggacctccggcgcgaccgtcgcctggcccggcaccggg cgacggctgccgttgcccggctacccgttcgaggagctgcgctgctggctcaccgagcgg atgtgggcgccgtcgccggccggcccggccacgcatccgctgctggacgagatcgtgccg gccgacagcgtggacggcctgaccttccgcaccgccttcgcccccgcgcatccgctgata gacgggcaccgcgtcggcgacctgcgcctgctccccgccgccgcggtgctggagatggcc cgggccgccgccgcgcacgccggataccccgtgccggtcaggctgcgcgacgttcggtgg ctacggccgctcgtggtcaccgggaccgtggcctccgcccgcacccggctgcgccgcgac ggcgccggcctggccttcacactgctcggcgacaccggcgaccaactggcccagggcctg gtcgaggcacgggccgacgacgtgccggagccggtacccgtcgagcggatccgggccgcc ctgccgcaccggcacgacggcgcggacctctacaccgacctggccggagccggcctggtc tacggcccggcgctgcgtgccgtcgagtggatcgcctccggcaccgacgaggcgctggcg agtctgcgcgtgcccgccgaagccgcccggttcgccgactgcgcactgccacccgcgctc atcgacggtgccctgcacacgttcgcggtgctgcgcgatcgcgccggcggcccgatggtg cccttcgcgctcgccgccgccgaggtggtcggaccgctgcccgagcatgtgtacgcccat gtgcgcaccgtcggcccggaccggtacgacctgaccctgaccgacccggacggcggcgtt ctcgtcctgctgcgcgacctgtgcctgcgcccggctcccgcagcggggacgtccgacgcc gggcccgccgtgaccgccgtgaccgccgggcccgccgtgaccgagcggccggtggatgac ctgatgtacctgccccgctggtccccggtcgcggccgagccgttcaccgtgccgtcgacc gcgcccggctcggacacctggctgatccgtccgtcctgcgccgcgcccctcgccgccgcc ctcgccacccggctcggcggttccgtcaccgagatcgagcccgagcacttcgtcgcaccg gccgggcgtcccggccacgtgatcgtgctgtccggcccggcgcaggggcgcaccgacgac cccgccgccctcgacctcgcgcaggagcgcggcgtcctggccctcttccgcgcagcgaag gcgctgcaacggtccggcgcacccgtacggctgacggtggtcaccgaggacgcgctgagt accggcaccgaaccggtccgcaacccgtacgcggcgagcctgcacggactggctctgtcc ctggcccaggagcagccgcgctggcgggtggccgtggtcgaccgctcctcggccgacccg atctccccggacgtcctcgacgtgccggccggtggcccgtacgccctgcgcgccggcgtc ctgcaccggcggagcctggtccccgccgcccccacgacgacgcgcgaggcgatacgccac ggcggtgtctacctgattctcggcggtgccggaggactcggcctggagctcaccgaatgg ctggtgcgcggctaccgggccaaggtcgtgctggtggggcgcagtgaactcgacgccggc cggcgcgaccggctgcgccgcctcgacccggccggcgccctcgtctcgtaccggcgggcc gacgccaccgaccccgcggcgctggccgaggtggtcacggcggtccgtgccgagcacggg acgctgcacggggtcgtgcacgccaccatcgtgctgcgcgaccagaccgtcgccacgatg accgaggacaccttccgggccgtgctcgacgccaagacccgcacgtcggtggcactgcac cgcgccctggtcgccgccgacgggctcgacttcgtcctgttcttctcctcggcggtggcc ctgtcgggcagcgccgggcaggccaactacgccgccggatcgacgttcgaggacgcgttc gcacaccatctcgacgacgtgctggccgcccgctcggccgtcgtcaactggggctactgg ggcaccgtcggcatcgtcgccgacgaccggcaccgcgagcgcctggcccggaccgggatc cactcgatcaccccggccgagggcatggcagccgtgcacgacgtgctgggccgcaccgat cggcaggtcgtcgtgatcaaggcgaccgccgaggtgctcgccgccgccggagtcgaacgg cccgccggtgaacggtccgacgacgagctggccccctcggcggcggcgctgccgccggtc gcccggctgttgaccgagaccgaccaggcgcgtctggacgaggtcgtgctcggctggctg tgggaactgttccggggcgaaggggtgttccggacggtcggcgaacggtggagcgccgac gagctgcggcggcggctgcggatcgccgacgggcagtcccgcctcttcgccgaactgctg cgcgtgctcaccgtcgccggtttcctgcgcgacgacggcagcgcgctgatcgccacggac cgccgggctcccaccgacccggagaacgaactggtcgtgctctgcgaggggcaacccgcg ctgaaccgcatcgaccggctgctgaggccctgcatgcaccagctgttcggggtgctccgc ggcaccgtccgcgcgaccgaggtgatgttccccggcggatccacggagctggtggagggc gcctaccggggcagcccggtggtcgaccgcgccaacgaactcgtggtcgccgccgtgctg gaccgggtgggccggctcggcggaccggtgacggtcgtcgaggtcggcgccggaaccggc ggcaccaccgcgagcctgctgcccgcgctggccgccaccggcgtggaactgacgtacgtc tacaccgacatctcgcccgccttcctgcagcacggccgacagcggttcgccgagcgctac ccgatggtgcgcttccagcagctcgacatctccggcgaccccctcgcgcagggcttcccg cccggcggcgcggacgtcgtggtcgcggcgaacgtcctgcacgccaccccggacctgccg cacaccctgcgcgcggtcgcgctgctgctcaaatccggtgggcacctggtgctcaacgag gccaccagcaacgtcgtcaccgccacgctcaccttcggtctgctcgacggctggtggctg caccgcgacaccggcctgcgtctgcccggttcgccgctgctgtccggacgcggctggcgc gccgcgctcgacctggccggattcacccgcagccgggctctgcccgccgacgaggggctc acgcagcacgtcgtcgtcgcggagagcgggccggccgggccggctgccgtcaccgcaccc acggcgcagccggcgccgccaccagcggccgaaccggcgcccgagccgcgtaccggcggc gggggccggctcgtcgaagccgcccgcgactacgtcaaggacgcgttcgtgcaggtactc gaggtgccccgggaccggctgtggctggacgagacgtacgagaacttcggggtcgactcg ctcaccgtgccccgcatcgccgacctgctcgccgagcgcatgggcgacctgccgcccact ctgctgttcgaacaccccaccatccgcgaggtcgccgaccacctggtcgagcggtatccg gaccgggtgcgggccctgctgcccgaccagccccggcccgcgccggcccaggccaccgag cccgcgccggcccaggccaccgagcccgcgccggcccaggtcaccgagcccgcgccggcc caggtcaccgagcccgccggacggccggcaaagacggcaccggccgcggacacccggatc gccgtcatcggcgtggccggccgctacccgctcgccgacgacgtcgacgcgttctggacc aatctgcgaaccgggctggactgcatccgcgaggtgccggccgagcgctgggatccgcgg acggagcccggggcgaacggcacaccggtcagccggtggggcggcttcctcgaccgcatc gacgagttcgacccgcggttcttccagatgtcgatgcacgaagccgagctgacggacccg caggagcggctgttcctgcagaccgcctggcacaccctcgaggacgccggctacccccgg acccggctccggggcagccgcgtcggcgtctacgtcggcgtcatgtacggccactaccag ctcttcgaggacgagcgcggcctggccggcgggatgggctacgcgtcgatcgccaaccgg gtctcgtacgcgctcgacctgcacggcccgagcctggcggtcgacaccatgtgctcgtcg tcgctgaccgccatccacctggcctgcgaggcgctggccgccggaggcgtggactacgcg ctcgcaggcggcgtcaacctcaccccgcacccacgcaagtaccggcagctcgcggccggc gggttcaccggcgagagcggccggtgccgcagcttcgcggccggcggcgacggcatggtc cccggcgagggggtcggcgcggtcctgctcaagccgctggccgcggccgagcgcgacggc gaccgcatcctcggcgtgatcctcggcagcgcggtcaaccacggcggcaagaccggcggg tacgcggtgcccagtcccggcgcccagagcgaggtcgtcacgagcgcgctgcgggccgcc ggcgtcgaaccggccgacgtgtcgtacgtggaggcgcacggcaccggtacggcgctgggc gacccggccgaggtcgccggactggcccgggcgttcggcgaccgcccggccggctcgatc gccatcggctccgtcaagtcgtccatcgggcacctggagtcggcggcgggcatcgccgcc ctgaccaaggtgctgttgcagatgcgcgccggggagctgacgccgtcactgcacgccgag cagctgaacccggccgtcgactgggcgaacgtcccgttccgcgtccagcgggaggcggcg ccgtggacgggcccgcgaccgttgcgcgccggcgtcagcgccttcggcgccggtggctcc aacgcccatctggtcgtcgagcagtaccgggccgagccacggcccggcgtcgtgccgatg ccggccgtgttcccgttctcggggcgcgacgcgcaggcgctgcgccgcatcgtcgagcgg atgctcagccgcctgcgggagctgggcgcgaccggcctgcgcggtgagccgggcgcgacc ggcctggcggagatcgccgcggccgccgggctgccggtcggcgccgtcgacgagccgctc gacgagctcggcctggacccggccacgatcatgcggctggcagggcgggagaccgccctg caccaaggcgccgtgcacagcggatcgacgctgcgacagctcgccgcggccccgccggac gcggcggacatcgacctcggccgcctgtcctacacgctgcagatcgggcgggaggcgatg gcacaccggctcgccgtggtcgcccaccggacggacgagctgatcgagcagctcgacgcc ttcctcgccgggcggcccgcgggctggaccggcgtggtgaccacggagccgggcgacccg gtcgcgccgagcgcggatccgcgcgacaacgcccgccgctgggtgcagggcgaggtgatc gactgggcgggcacggccggcagcgcgccggaaccgctgccactgcccggctacccgttc gagccggtccgctgctggatccgttccgcggccccgcgggccgccacgccgacgcccacc cggccggccggctcctccggccccgcgctgaccaccgtgctgcggctggtcagcggggtc accggctacccgatgacggagctggacccggccgcctcgttccacgaccacggcctggac tcgctggcgctgctgaggctggccggtgacgtctccgcggcgttcgacctaccggtcggc ccggaccagctgctggccacgccgacggccgcggccctggccgactggctcgcccgcgaa cacccgcagggcgcgcccgcgcgacccgcggagccggaaccggacgacccggtggtgatc gtcggcatggccgggacgctgcccggctccgccgacctggacgagttctgggccgccctg gaacgcggtggcgacctgttcaccgaggtaccggccgaccggtgggacgcacgggagcat cacggcgacccggccgcgcacccggaacgcacccgggtgacccgggccggcttcatcggc ggcatcgaccggttcgacccgctgttcttcggtatctccccgcgcgaagcccgctggatg gacccgcgccagcggctgctgatgcgtacggtgtgggccgcgctggaggacgcgggtatg gacccgggtgctctggccggcagcgacaccgggctcttcgtcggcgtcggctccggcgag tacgccgaactcgtccagcgctccggcgccgccaccgacgcctactcgtcgaccggcctg gccccgtcgatgctggccaaccgcatctcgtaccagctcgacctgcacggtcccagcgaa cccgtggacaccgcctgctccagctcgctcgtcgcgctgcaccgggcggcggaggcgctg cgcctcggacggtgcggcacggtcatcgtcggcggcgtcagcctgatgctgtccccggtc accttcgcctcactggaacgggcggggatgctcagcgaggacggcgtgggccgggccttc gacgccgacgcgtccggttacgtacgcggcgagggggtcggcgccgtcgtcctcaagcgg ctcagccgggcgcgcgccgacggcaacccgatcctggccgtactgcgcggcaccgcggtc aaccacggcggccgagccaattcgctgaccgcgccgagcccgcgcgcacaggcagacgtg atccggcgggcgcaccgggaggcggcggtcgacccggcgacgatcggctacctggagacg cacggcaccggcacggtcatcggtgaccccgccgagaccaacgggctgcgcgaggcgttc gccgacctctaccaggactggggacacgacgcgccggcccggccgcactgcgcgctcggc gcgctgaagaacaccatcggccatctcgaaccagccgccggcatcgccgcggtgctgcgc gtgctgctgtcgatgcggcacggccggatcaccggcgacccgcacgggccgcggccgaac ccgcatctgggcctggagggcaccccgttcgaactcgcgaccgggccgcgggagtgggcg ccgcccgcgcccggggtgccacgcagggccggggtgagcgccttcgggtacggcggagcc aacgcgcacgtcgtactcgaggagtacccggccgaggagccggttccggcgccgggaccg gtcgtgttcgtcctgtccgcccgggaccccgaacggctgcgggcgtacgcgcggtccttc gccgaccggccggaccgctgggcgcacgacctggcgagcaccgcgtacacgttgcaggtc gggcgcggggcgtaccccgagcggctggcgttcgtcaccgactccgccgagcacgccgtc gcgacgctacggcgtttcctcgccggtgacaccgcgggcatccacaccggtcgggtcgag cgggacgcggaccgcacgccctgcgacggccgcggtgacgacgagacggcggccgcctgg acccggggcgcacaggtggactggcatcgccgctgggccgccccgccccgccggcggtcg ctgccgacctacccgttcgcgcaggaacggcactggttcaccgatggcacgactgcccgt ccggtcagctgcttcacggcgacctggcaggacgagccggtcccggcggccggcgagcac ccgggccgggtactggtcctgggcgatctgccggtgcccggcgccgtgcacgtgcgcgcc ggcacggagtaccgcgacgagggcccggtgatcaccatccggcccggcgagcaggacgac tacgcgcggctgctcgccgagacgcccgcccggatcgtccaccagtggccgctgctcgcg cccggccgcgacgacctgggactcgaggcgatgttccggatcgcgaaggagctgacggcc ggcgccgcccgcaccccggtccggatccaggcgctggtgccggaggacgcgctcgccgag gcgtggggcgggttcgacgcgtcgttgcgggccgcgctgccgggaacgacgttcggcgtc gtccgggtcgacggtgcgggcgacaccggcgagctgctcgccgagatcgccgcgcaccgg ctgtcgggcccggccgtgcggctgtcgccgtcgggccggtcggtgcgggtgctcagcgag atacccgcccgtccggtgctgccctcaccgctgcgtgacggcggcgtctatctgatcacc ggtggcctcggcgggctgggtgtgctgctggcccgaacgctgctgtcacgtggcgcccgg gtggcgctgaccggtcgctcgccggccgccgaacgggccgagcagctggcggagctgcgc gcgcacggcaccgtcgcgtactaccgggcggccgtggaggaccgcgacgcgatgacccgc gtggtggccgaggtgatcgccgacctgggcggcctcgacgggctgttccacctggccggc accgcgtcgcgcaacccgcttcccggcaaggacgtcgacgagctgcgggcgcacctgcgc gcccggatcaccggaaccagggttctcgacgaggtcacccgcgacctgccgctggacctg ttcgtgctctactcctcgctggccgggcagctcggtgactacggcctggtggactacgcg gtcggcgctcgctacctcgacgggttcgcggacttccgggagcgggagcgtctcgccggc cgccgccacggccgtaccgtgtcggtggactggccgatgtggcgtgccggcggcatgcac gtggacaccgacgacgagcgccgctacctggccggtaccggcttccgctacctggagacg gccgagggcgagcaggtgctcgacctggtgctgcgcctggaccgcccgcaggtggccgtc ctgcccggtgacccggcccggatgcgcgacctggtcgccgggatgcgtctgcgcgacgac ggcgtaccggccctcccggcgccgccgccgacccccgcgccggccgtcgccgtctccccg gaactccccacccagctgcgggagctgatcggcgggatcctcgggatcgccccgtccgct ctcgaccccgacgccggcttcggcgagtacggcctggactccttcggcctgcagaacctg gccgcggcactggccgcccgttacgacgtgaccgtgccgacgacgacgctgttcggcgcc aacacggtcaccaagctcgccgcgcacctggcggccgagctgcctccggccccggtggcc aagcggaccgagcccggccccgcgtcgtccgagcccggccccgcgtcgtccgagtccgcg cccgcaccggtgtccgtgccgcacggcgtgcccgcgcccgcaccggtgtccgtgccgcac ggcgtgcccgcgcccgcgagcggctcgtcgtccgccgctccggccggtcatgagccgatc gccatcatcggcctggccgggcggctgcccggcgcggacgacctcgaacagttctggcag cacctcgccgacggccgggacctgatcaccgagacgcccgccgaccgatgggactggcgg gaggtcgcccgccgcttcggcggcaccgcccgctggggtggcttcctgacaggcgtggac ctcttcgacccgctgttcttccgtatctcaccggccgaggcgcaggccatggacccgcag caccgcctcttcctggagcacacctggggcgcgctggaggacgccgggtgccgcccggac cggctcgcgggcggccgggtgtgcgtcttcgccggggtgcagttcgccgactacgagtcg atggtgctgcgcggcgagcacgtcaacgctcacgccggcaccggtctggcccgcaccatg ctggccaaccgcatctcgtacctgctcgacctgcggggcccgagcgagagcgtcgacacg gcctgctccagctcgctggtcgccctgcaccgtgccgtgcggtcgctgcgcgcgggggag agcgacctcgccatcgccggtggggtgagcctcgtgctgtccccgcagaccgtggtcgcc ggcaaccagctcggcgtgctcgcgcccgacggccggtgcaaggcgctcgacgagagcgcc gacgggtacgtcaagggcgagggggtcggcgtcgtcgtgctcaagacgctgtcgcgggcc ctcgccgacggcgaccgggtgcacgcggtgatccgcggcagcgccgtcaaccacggcggc cgcgcgtcgtcgctcacctcgccgaacccgctcgcgcaggcggatctgctggtcgaggcg tacggggacgcggacgtgccgatcgagacggtgtcctacgtcgagctgcacggcaccggc accgccctgggcgacccggtcgagatcgacggcctggtccgcgcccatcgcgcgctggcc gccgggccgccggtcacctgcggcatcggcacggtcaagagcaacatcgggcacctggag cccgcggcgggcatcgccggcgtgatcaaggtggtgctggcgatgcggcaccggcagctg ccgccgaccctgcacctgtcgcggctcaacccgctgatcgacctggacggcactcccttc gagccggtccgcgagacccggccgtggacaccgagcgacgccgacggcacgaccgtgcca ctgcgcgccggggtcagttccttcggcttcggcggggtcaacgcccatgtcgtcctggaa gagccgcccgtgacgtccgtgcccgtggactccacggggccggagatcttcgtgctgtcg gcgcgggacgaggccgccctgcaccggtacgcccgggcacacctggcattcctcggcgac cggcagcccgcgctctcctctctcgcccacacctcgcaggtgggccgggttccgatgccg gtgcgcctggccctggtcgtcaggtccgtggccgaactgcgggaccggctggccgccttc ctggccggtgacatcgaggcgaccaccgcgaccggcgaccacgactggctcaccgagccg gagggcgtcagctacctgcgccggctggcccgggaagggcggctcgatcggatcgcccgc ctctggcaggccggcgcggccgtggactgggccgcgctgcgcaccgatcggcccgccctg acgtccatgccgacgtacccgttcgcccgggaacggcactggctggcgagcccgtccgcc gcgccgccggagcacgaggcgcgacgcctgctggccaaggagtgggaaccggcgccggcg gcgtcggggccggcgccgaccgcgccggtggtcctggtccgggccgagaccgaggcgctg gcgacggcggcgttcggtgacacggcccgagtggtccgcctggacgacacggacgaggag acggggctgcgggcggccgcgtcgatcggccgggcgccggtcgtgatcgacctcgtcgac ctgtccgcggtgccggtgcccgacgtacgcgtcgactgggcccgcatcgtgctggcccgt gagctgatcgcgacgaaccgaaccgccggcttcgcctatctgcacctgacccgaggactg gtgtccttccgcgcgcacagcccgacgctgcgaggagcggcgttcgcgggactggtccgg atgctctccgccgagtaccgcggggtgttcgcccgcaccgtcgacgtcgacttcacggac ccggacgcgctgcgcgacgtggccggcgcggagctggcggcgaccgacccggtcaccgag gtgtgcgtgcgtgacggcgtccggtacacgccgacgctgcgtcccaccggctgcgccacg gcacccgcccggtggtcggacgatctggccgggcggccggtggtgatcaccggcggcacc ggcgcgctcggccgtctgctggccgcggaactcgtcgagcggggagcaaaccggctggta ctgctcggccagtccccgctgcccgcccgcgacaactgggcggagctgatggccgcaccc gacaccgatccggcgctggcggcccgactgcgcgacctcagcgcgctggaacgcgccggg gtgcgcctggtgatcgagagcatccccctcgagcgcgcccgggaggtactggaccggatc cggcgggagtggggaccgatcgccgggatcgtgcactgcgccggtctcggcgtgatgacc gacccggctttcatcggcaaacgcaccgccgacatgcggcgggtggtggaaccgaagacc acgggcctgcaggcgctcctggacgcgtgcggcgacgacccgctgcgcttcgtggtgctg tactcgtcgatcgccggtcaggtgcccgcgctggcggcagggatgagcgactacgcgctg gccaactcggtgctggaccgggtggccgagtaccggaacgccaccggcgccgacacgccg gtcttccggtcggtgcagtggccgagctggcaggcggccggcatgccggaggtggacacc cctgtctaccgggaactggggctgcggacgctgcgcccgcaggacggcgtggcgctgctg gacgcggcgctggcgggacccgacccggtcgtgctgccgtgcctggtggacaccacccgg ttcgacgcccgggccttgttggaggttgccgtgcccgggagttctgtgcccgggacttcc gcgccggggactcccgtgcccggggcgtccgggcccgggacttccgcgccggggactccc gcgcccagggcgtccgggcccgggacttccgcgctcgaaaccaccgatcccgggacttcg gtgcccgggcaccccgcgccaggggccttggcgccggtcgccgccgcggacccgcccacg gctcacgggaggcggaccggtgacggcgtgcggaggctcaccgaggtcttcgcgacgacg ctgcggctggacgccgcccagatccggcccgacgccgacttcgccgacctcggtgtggac tccatcatgatcgtccaactgctcgccgcgctggaacgtgacctcggggtggtcgccgaa ccctcggcgctgctggagaacccgaccatcgcccggctggccgccgccctcgacgaccgg ctgccggagcagcctgcgcccgggaagccggagccggtgcgcgcgccgcagccgcgaccc gcccaggtgagagggccggagcggggaatcgcggtggtgggcattgccgcccacttcccc ggagcgcccgaccacgccacgttctggcgcaacctcgtcggcggcgtggactcggtgacc gaggtgccgccgtcgcgctgggatgccgatcgcttctggcaccccgccccgcagcccggc agaaccgtcagcaagtggggcggattcctggacggcatcgaggacttcgacccggactac ttccggctcgacccggccggggccgcccacgtcgacccgctggtgcggcagttcctggag gccggggcggagtgcctggccgacgcgggcctgacgcccgccgaagtggccggtcgccgg gtcggggtcttcgccggcgcccgggcggcgaacttcggcgcgcaccatgccgccgcgacg acccactcgatcagcggcatggcgcagaacttcatcgccgcccacctctcgcactacctc gacgtgcgcggccccgccgtcgtcgtcgacagcgcctgctcctcggcgctggtcgcggtg cacctggccgcgcagagcctgcgcaccggcgagtccgacctggtgatcgccggcggcgtc gagatcctgctcgacgaggtgccgttcgtcggcatgagcggcgcgggggcgctgtcaccg agcggccggtgccacaccttcgacgagcgcgccgacggcatcgtcctcggcgagggcgtc ggcgccctgctgctcaagcgggccgaggacgcgatccgcgacggcgaccgggtgtacgcg gtgatcgagggcagcgccgtcaacaacgacggccgcaccatgggcatcaccacgccgaac ccgagggcgcagcgcgaggtcgtcgagtccgcactcgccgcggccgaggtgtcaccggtg cagctcggctacgtcgaggcgcacggtaccggcaccatgatcggtgacccgatggagctg aaggcgctcaccgaggtcctgcgcggcgccaccgacgaggtcggcttctgcggtgtgggc agtgtgaagaccaacatcgggcacacgctcagcgcggccgggatcgccggcctgatcaag gtggtgctgtcggtgcaccacgggcaactgccgcccaccttgcactgcgcgacgctcaac cggcgcttcgagttcgaccggtcgccgctgttcccggtccgtgagctgcgggactggacc gggcgggacggcgtacgccgggccggagtcagctcgttcggcttcggcggcaccaacgcc cacatggtggtgcgccaggccccggacggccatgtcccgctgcgtgaaccgctggatccg ccgcgctaccgacggcgccggttctggttcgacgtcccggtaccggcctccgcaggagcc aacgggcgccacgacggcccgacgccgccggcgccgttcttccagatccagttctga

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