Spermophilus citellus (European ground squirrel): 308635573
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Entry
308635573 CDS
T11988
Symbol
NOS2
Name
(RefSeq) nitric oxide synthase, inducible isoform 1
KO
K13241
nitric-oxide synthase, inducible [EC:
1.14.13.39
]
Organism
scil
Spermophilus citellus (European ground squirrel)
Pathway
scil00220
Arginine biosynthesis
scil00330
Arginine and proline metabolism
scil01100
Metabolic pathways
scil04020
Calcium signaling pathway
scil04066
HIF-1 signaling pathway
scil04146
Peroxisome
scil04371
Apelin signaling pathway
scil04926
Relaxin signaling pathway
scil05010
Alzheimer disease
scil05014
Amyotrophic lateral sclerosis
scil05022
Pathways of neurodegeneration - multiple diseases
scil05133
Pertussis
scil05140
Leishmaniasis
scil05142
Chagas disease
scil05145
Toxoplasmosis
scil05146
Amoebiasis
scil05152
Tuberculosis
scil05200
Pathways in cancer
scil05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
scil00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
308635573 (NOS2)
00330 Arginine and proline metabolism
308635573 (NOS2)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
308635573 (NOS2)
04066 HIF-1 signaling pathway
308635573 (NOS2)
04020 Calcium signaling pathway
308635573 (NOS2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
308635573 (NOS2)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
308635573 (NOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
308635573 (NOS2)
09162 Cancer: specific types
05222 Small cell lung cancer
308635573 (NOS2)
09171 Infectious disease: bacterial
05133 Pertussis
308635573 (NOS2)
05152 Tuberculosis
308635573 (NOS2)
09174 Infectious disease: parasitic
05146 Amoebiasis
308635573 (NOS2)
05145 Toxoplasmosis
308635573 (NOS2)
05140 Leishmaniasis
308635573 (NOS2)
05142 Chagas disease
308635573 (NOS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
308635573 (NOS2)
05014 Amyotrophic lateral sclerosis
308635573 (NOS2)
05022 Pathways of neurodegeneration - multiple diseases
308635573 (NOS2)
Enzymes [BR:
scil01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
308635573 (NOS2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
NAD_binding_6
DUF2478
Motif
Other DBs
NCBI-GeneID:
308635573
NCBI-ProteinID:
XP_081126120
LinkDB
All DBs
Position
17:32221661..32258443
Genome browser
AA seq
1170 aa
AA seq
DB search
MRERLSAACEAARPRLCRFLRWILRAKPSRRPCAASPGTQDDPKCHNLIRHQNGSPPPLP
EMAKKSPESLGPLNVPPPSCSEHVRIKNWGNGMTLQDTLHHKAKSDFTCKSKSCLGSIMN
PKSLTRGPRDKPISLDELLPQAIEFVNQYYASFKEAKIEEHLARVEAVTKEMETTGTYQL
TGDELIFATKLAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHLCRHIRYATNNGNIR
STITVFPQRSDGKHDFRVWNSQLIRYAGYQMPDGTIRGDPANLEFTQLCIDLGWKPRYGR
FDVLPLVLQADGRDPEFFEIPPELVLEVPMEHPKFEWFRELDLKWYALPAVSNMLLEVGG
LEFPACPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLEMHTLASLWKDRAVTEINVA
VLHSFQCLLLCWNIPIGVQAGYPRSHLQKRNVTIMDHHSAAESFMKHMQNEYRARGGCPA
DWIWLVPPISGSITPVFHQEMLNYVLSPFYYYQVEPWKTHVWQDEKRRPRRREIRFKVLG
KAVLFASMLIRKTMSSRVRVTILFATETGKSEALAQDLGTLFSCAFNPKVLCMDEYSLSD
MEQERLLLVVTSTFGNGDAPGNGQTLKKSLLMLKELTNTFRYAVFGLGSSMYPQFCAFAH
DIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWALHTFKAACDTFDIRGKHHIQIPKLYT
GSMTWEPRHHRLVQDSQPLDLNKALSHMHAKKVFTMRLKSQQNLQSPKSSRTTLLVELSC
EDSTDLSYLPGEHLGVFPSNQLALVQGILERVVDSPAAQQTVRLEALDDSGSYWIRDKRL
PPCSLSQALTYFLDITTPPTPLQLQKLARLATEESERQRLETLCQPSEYNKWKSTNSPTF
LEVLEEFPSLRVPAAFLLSQLPLLKPRYYSISSSRDHTPTEVHLTVAVVTYRTQGGQGPL
HHGVCSTWLSSLMPQDPVPCFVRSASSFQLPEDPSHPCILIGPGTGIAPFRSFWQQRLHD
SEHKGLQRGHMTLVFGCRHPEEDHLYREEMLEMARKGVLHEVHTAYSRLPGKPKVYVQDI
LRQQLAGEVLRVLHESPGHLYVCGDVRMARDVAHTLKQLVATKLSLSEEQVEDYFFQLKS
QKRYHEDVFGAVFPYEVKKDRAAGQPNTGL
NT seq
3513 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgaaaggctgagcgccgcttgcgaagcggcccggccgcggctgtgccgttttctg
cgctggatcctccgagcaaagccctcccgccgcccctgcgcagccagtccagggacacag
gatgaccccaaatgtcacaacctcatcaggcaccagaatggatctccccctcccctcccg
gagatggcaaagaagtctccagaatctctgggtccgctgaatgtgcctcctccatcctgc
tcagagcacgtgaggatcaaaaactggggcaatgggatgactttgcaagacacgctccac
cacaaagccaaatcggatttcacttgcaagtctaaatcttgcctggggtcaatcatgaac
cccaaaagtttgaccagaggacccagggacaagcctatctctctggatgagcttctacct
caagctattgaatttgtcaaccagtattacgcctccttcaaagaggcaaaaatagaggaa
catctggccagggtggaagcggtgacaaaggagatggaaacaacaggaacctaccagctg
actggagatgagctcatctttgccaccaagctggcctggcgcaacgccccccgctgcatc
gggaggatccagtggtccaacctgcaggtctttgacgctcggagctgttccaccgcccag
gagatgtttgaacacctctgcagacacatccgttatgccaccaacaacggcaacatcagg
tcgaccatcactgtgttcccccagcggagcgatgggaagcacgacttccgagtctggaat
tctcagttaatccggtatgccggctaccagatgcctgatggcaccatcagaggggaccct
gccaacttggagttcacccagctatgtatcgacttgggctggaagcctcgttatggccga
ttcgatgtgctgcctctggtcctgcaggctgatggccgtgaccctgagttctttgaaatc
ccacctgaacttgtgcttgaggtgcccatggaacatcccaagtttgagtggttccgcgag
ctggacctgaagtggtatgccctgccggctgtgtccaacatgctgctggaggtgggtggc
cttgagttccccgcgtgccccttcaatggctggtacatgggcactgagatcggagtccgg
gacttctgtgatgtccagcgctacaacatcctggaggaagtggggagaaggatgggcctg
gagatgcacacgctggcctccctctggaaagaccgggctgtcacagagatcaacgttgct
gtgctccatagcttccagtgtctccttctctgctggaacattccaatcggtgtgcaggca
ggctatcctaggtcccatctgcagaagcggaacgtgaccatcatggaccatcactcggcc
gcggagtccttcatgaagcacatgcagaatgagtaccgggcccgcgggggctgccctgca
gactggatttggctggtccctccaatttctgggagcatcacccctgtgtttcaccaggaa
atgttgaactatgtcctgtccccattctactactatcaggtggagccctggaagacccat
gtctggcaggacgagaagcgtagacccaggagaagagagatccgattcaaagtcttgggg
aaagctgtgctctttgcctctatgctgattcgcaagaccatgtcatcccgagtcagagtc
acgatcctctttgcaactgagacaggaaaatcagaagcgctggcccaggacttggggacc
ttgttcagctgtgccttcaaccccaaggtcctctgcatggatgagtacagcctgagcgac
atggagcaggagcggctactgctggtagtgaccagcacatttgggaatggagatgcccct
ggcaacggacagactctgaagaaatccctcttgatgctgaaggagctcaccaacaccttc
aggtatgccgtgttcggtcttggctccagcatgtacccacagttctgtgcgtttgctcat
gacatcgaccaaaagttgtcccacctgggagcctctcagctcaccccaatgggggaaggt
gacgagctcagcgggcaggaggatgcattccgtagctgggccctgcacaccttcaaggct
gcctgcgacacgtttgacattcgaggcaagcaccacattcagatccccaagctctacacg
ggcagcatgacctgggagcctcgccaccacaggcttgtgcaggactcacagcccttggac
ctcaacaaagccctcagccacatgcacgccaagaaggtgttcaccatgaggctcaaatct
cagcagaatctacagagtcccaaatccagccgcaccaccctcctggtggagctctcctgc
gaggacagcacagacctgagctacctgcctggagagcacctcggggttttcccaagcaac
cagctggccctggtccaaggcatcttggagcgagtagtggacagccccgcagcccagcag
actgtgcgcctggaggccctggatgacagcggcagctactggatcagggacaagaggctg
cccccctgctcgctcagccaggccctcacttacttcctggacatcaccacgcccccaacc
cctctgcagctccaaaaactggccaggctggccacagaggagtctgagagacagaggctg
gagaccctgtgccagccctcagaatacaacaagtggaagtccaccaacagccccacgttc
ctggaagtgctggaggagttcccatcgctgcgggtaccggctgccttcctgctctcccag
ctccctcttctgaaaccgcgctactactccatcagctcctcccgggaccacacacccaca
gaggtccacctcaccgtggccgtggtcacttaccgcacccaaggtggccagggtccactg
caccacggcgtctgcagcacgtggctcagcagcctgatgccccaggacccagtgccctgc
tttgtgcgaagtgccagcagtttccagctgcccgaggacccctcccatccctgcatcctc
attgggcctggcacaggcatcgcgcccttccgcagtttctggcagcagcggctccatgac
tctgagcacaaagggctccagagaggccacatgaccctggtgtttgggtgccgccaccca
gaggaggaccacctgtatcgggaggagatgctggagatggcccggaagggggtgctgcat
gaggtgcacacagcctattctcggctgcccggcaagcccaaggtctatgttcaagacatt
ctgcggcagcagctggctggtgaggtcctccgcgtgttgcatgagtccccgggccacctc
tatgtctgtggggatgtgcgtatggctcgagatgtggcccacaccctgaagcagctggtg
gccaccaagctgagcttgagtgaagagcaggttgaggattatttcttccagctcaagagc
cagaagcgctatcatgaagatgtctttggtgctgtgtttccctacgaggtgaaaaaggac
agggccgcgggacagcccaacacaggcctctga
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