Spermophilus citellus (European ground squirrel): 308655913
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Entry
308655913 CDS
T11988
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform 1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
scil Spermophilus citellus (European ground squirrel)
Pathway
scil01521
EGFR tyrosine kinase inhibitor resistance
scil04151
PI3K-Akt signaling pathway
scil04217
Necroptosis
scil04380
Osteoclast differentiation
scil04550
Signaling pathways regulating pluripotency of stem cells
scil04620
Toll-like receptor signaling pathway
scil04621
NOD-like receptor signaling pathway
scil04630
JAK-STAT signaling pathway
scil04658
Th1 and Th2 cell differentiation
scil04659
Th17 cell differentiation
scil05140
Leishmaniasis
scil05145
Toxoplasmosis
scil05152
Tuberculosis
scil05160
Hepatitis C
scil05161
Hepatitis B
scil05162
Measles
scil05163
Human cytomegalovirus infection
scil05164
Influenza A
scil05165
Human papillomavirus infection
scil05166
Human T-cell leukemia virus 1 infection
scil05167
Kaposi sarcoma-associated herpesvirus infection
scil05168
Herpes simplex virus 1 infection
scil05169
Epstein-Barr virus infection
scil05171
Coronavirus disease
scil05200
Pathways in cancer
scil05203
Viral carcinogenesis
scil05212
Pancreatic cancer
scil05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
scil00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
308655913 (JAK1)
04151 PI3K-Akt signaling pathway
308655913 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
308655913 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
308655913 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
308655913 (JAK1)
04621 NOD-like receptor signaling pathway
308655913 (JAK1)
04658 Th1 and Th2 cell differentiation
308655913 (JAK1)
04659 Th17 cell differentiation
308655913 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
308655913 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
308655913 (JAK1)
05203 Viral carcinogenesis
308655913 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
308655913 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
308655913 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
308655913 (JAK1)
05161 Hepatitis B
308655913 (JAK1)
05160 Hepatitis C
308655913 (JAK1)
05171 Coronavirus disease
308655913 (JAK1)
05164 Influenza A
308655913 (JAK1)
05162 Measles
308655913 (JAK1)
05168 Herpes simplex virus 1 infection
308655913 (JAK1)
05163 Human cytomegalovirus infection
308655913 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
308655913 (JAK1)
05169 Epstein-Barr virus infection
308655913 (JAK1)
05165 Human papillomavirus infection
308655913 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
308655913 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
308655913 (JAK1)
05140 Leishmaniasis
308655913 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
308655913 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
scil01001
]
308655913 (JAK1)
Enzymes [BR:
scil01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
308655913 (JAK1)
Protein kinases [BR:
scil01001
]
Non-receptor tyrosine kinases
JAK family [OT]
308655913 (JAK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
308655913
NCBI-ProteinID:
XP_081162462
LinkDB
All DBs
Position
9:86271206..86410709
Genome browser
AA seq
1157 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKAEVNQVAPEPGVEVTFYLPDREPLRLGSGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITIDDKISLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKVQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSPHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WLHSNDNGNVLSYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIQ
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGNEEGMYVLRWSCTDFDNILMTVT
CFEKSEQVLGTHKQFKNFQIEVQKGRYSLHGSDRNFPTLEGLMSHLKKQILRTDNISFVL
KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGDHLGRGTRTHIYSG
TLVDYKDDEGAAEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
VENIMVEEYVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
LLAREGIDSEIGPFIKLSDPGIPVTVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDS
ESSPMALFLKMIGPTQGQMTVTRLVNTLKEGKRLPCPPNCPDKVYQLMRKCWELQPSNRT
TFQSLIEGFEALLKYEA
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaagactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaaggcggaggtgaatcaggtggcccctgagccaggggtggaagtgaccttc
tatctgccagacagggagcccctccggctgggcagtggagagtacacagcagaagagctg
tgcatcagggcagcgcaggaatgctgtatatctcctctatgccacaacctctttgccttg
tatgatgagaacaccaagctctggtatgctccgaaccgcaccatcaccattgatgacaag
atatcactccgactgcactaccgcatgaggttctacttcacaaactggcatggaaccaat
gacaatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaag
aaaaaggttccagatgcaacccctctccttgatgccagctcgctggagtacctgtttgct
cagggtcagtatgatttggtcaaatgcctggctcccattcgggaccccaagactgaacag
gatgggcatgatattgagaatgagtgcctggggatggctgtcttggccatttcgcactat
gccatgatgaagaaggtgcaattgccggaacttcccaaggacatcagctacaagcgatat
attccagaaacattgaataaatccatcagacagaggaaccttctcaccaggatgcggata
aataacgttttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagt
gtgtcccctcatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat
tatggggctgaaatatttgagacttctatgttattaatttcatcagaaaatgaaatgaat
tggcttcattcaaatgacaatggaaatgttctctcctatgaagtgatggtaactggaaat
cttggaatccagtggcggcagaaaccaaatgttgttccagttgaaaaggaaaaaaataaa
ctgaagcgaaaaaaactggaaaataaacataagaaggatgaggagaaaaataaaatccag
gaagaatggaataatttttcttatttccctgaaatcactcacattgtaatcaaggagtct
gtggtcagcattaataagcaggacaacaaaaaaatggaactgaagctttcttcccatgag
gaggccttgtcctttgtgtccctggttgatggctacttccggctcacagcagatgcccat
cattacctctgcactgatgtagctcccccattgatagtccacaacatacagaatggctgc
catggtccaatctgcacagaatatgccatcaataagctacggcaagaagggaacgaggag
ggaatgtacgtgctgaggtggagctgcaccgactttgacaacatcctcatgactgtcacc
tgctttgaaaagtctgagcaggtgctgggtacccataagcaattcaagaattttcagatc
gaggtacagaagggccgctatagcctgcatggctcagatcgcaacttccccaccctggaa
ggcctcatgagccacctcaagaagcagatcctgcgcacagacaacatcagctttgtgctg
aagcgctgctgccagcccaagcctcgagaaatctccaatctgttggtggccaccaagaag
gcccaggagtggcagcctgtctaccccatgagccagctgagctttgaccggatcctcaag
aaagatattgttcaaggtgatcaccttggcagaggcacaagaacacacatctactctggg
accttggtggattacaaggacgatgaaggggctgctgaagagaagagaataaaagtgatc
ctcaaagtcttagaccccagccacagggacatttctctggccttctttgaagcagccagc
atgatgagacaggtctcccacaaacacattgtgtacctctatggcgtctgtgtccgagat
gtggaaaatatcatggtggaagagtatgtggaggggggacccctggatctctttatgcat
cggaaaagcgatgtcctcactacaccatggaaattcaaagttgccaaacagctggccagt
gccctgagttacttggaagataaagacctggtccatggaaatgtgtgtaccaaaaatctc
cttctggcccgtgagggcattgacagtgaaattggcccattcatcaagcttagtgaccct
ggaatccctgtcactgtactgtcaaggcaagagtgcatagaacgaatcccatggattgct
ccagagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggt
accacactctgggaaatctgctataatggcgagatccccctgaaagataagactctgatt
gagaaagagagattctatgaaagccggtgcaggccagtgacaccatcatgcaaggagctg
gctgaccttatgacccgctgcatgaactatgaccccaatcagagacccttcttccgagcc
attatgagggacattaacaagctcgaagagcaaaatccagacattgtttcagaaaaaaaa
ccagcaactgaggtggatcccacacattttgaaaagcgcttcctgaagaggatccgtgac
ttgggagagggccactttgggaaggttgagctctgcaggtatgacccagagggggacaac
acaggggagcaggtagctgtcaaatccttgaagcctgagagtggaggtaaccacattgct
gatctgaagaaggaaatagaaatcttaaggaatctctatcatgagaacatcgtgaagtac
aaaggaatctgcactgaagatggaggaaatggtatcaagctcatcatggagtttctgcct
tctggaagccttaaggaatatcttccaaagaataagaacaaaattaaccttaaacagcag
ctaaaatatgctgttcagatttgtaagggaatggactatttgggttctcggcaatatgtt
caccgggacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattgga
gactttggtttaaccaaagcaattgaaactgataaggagtactacaccgtcaaggatgac
cgggacagccctgtgttttggtacgctccagaatgtttaattcagtgtaaattttatatt
gcctctgatgtctggtcttttggagtgactctgcatgagctgcttacttactgtgattca
gagtctagtccaatggctttgttcctgaaaatgataggcccaactcaaggccagatgacg
gtaacaagacttgtgaacacgctgaaagaaggaaaacgtttaccatgcccgcctaactgt
cctgataaggtttatcaacttatgagaaaatgctgggaattacaaccatccaatcggaca
acctttcagagccttattgaaggatttgaagcacttttaaaatacgaagcatga
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integrated database retrieval system
