Streptomyces cinereoruber: CP977_09360
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Entry
CP977_09360 CDS
T07115
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scin
Streptomyces cinereoruber
Pathway
scin00300
Lysine biosynthesis
scin00550
Peptidoglycan biosynthesis
scin01100
Metabolic pathways
scin01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scin00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CP977_09360 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CP977_09360 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CP977_09360 (murF)
Enzymes [BR:
scin01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CP977_09360 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
QEV32352
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Position
complement(2128572..2129996)
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AA seq
474 aa
AA seq
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MIALSLAEIAEIVGGQAHDIPDPAARITGPVVIDSREVREGSLFAAFAGERVDGHDYARR
AVEAGATAVLAARPVGVPAIVVDDVQTALGALARAVVERLGTDVVALTGSAGKTSTKDLI
AQVLERHAPTVWTPGSLNNEIGLPLTALTATDETRHLVLEMGARGIGHIRYLTTLTPPRI
GLVLNVGSAHIGEFGGREQIALAKGEMVESLPTEAEGGVAVLNADDPLVRAMADRTKARV
TLFGEADEAAVRAENVHLTETGRPSFRLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHEL
GMPVEEIATALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGRAAQ
ARGARTWAVLGKMAELGDASLVEHDAVGRLAVRLNVSKLVAVGDREASWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLEQVALALLDTEGEVTGR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgaaatcgtcggcgggcaggcgcacgacata
ccggatccggccgcccggatcaccgggcccgtcgtcatcgactcccgcgaggtgcgggaa
ggcagcctcttcgccgccttcgccggtgagcgcgtcgacggccacgactacgcgcggcgc
gccgtggaggcgggtgcgacggccgtgctcgccgcccgccccgtcggcgtgcccgcgatc
gtcgtggacgacgtccagaccgccctcggggccctcgcccgcgccgtcgtcgaacgcctc
ggcaccgacgtcgtcgccctcaccggctcggcgggcaagacctccaccaaggacctgatc
gcccaggtcctggagaggcacgcgcccaccgtgtggacgcccggttcgctcaacaacgag
atcggcctgcccctcacggcgctcaccgcgaccgacgagacccggcacctggtcctggag
atgggcgcccggggcatcggccacatccgctacctcaccaccctcaccccgccccgcatc
ggcctcgtcctcaacgtgggctccgcccacatcggcgagttcggcggccgggagcagatc
gccctggcgaagggcgagatggtcgagtcgctccccaccgaggccgaggggggcgtggcg
gtcctcaacgccgacgaccccctcgtccgcgcgatggccgaccgcaccaaggcccgcgtg
accctgttcggcgaagcggacgaagcggccgtacgtgccgagaacgtccacctcaccgag
accgggaggccctctttccgccttcacacacccaccgggtgcagcgacgtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcgcacgagctg
ggcatgcctgtcgaagagatcgccaccgcgctctccgaggccggctccctgtcgcgctgg
cgcatggaggtcaccgagcgtccggacggcgtgacgatcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgggccgccctgcgcgcgctcgcggccatgggccgggccgcacag
gcccggggggcccgtacgtgggcggtgctcggcaagatggccgagctcggggacgcatcg
ctcgtcgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtg
gcggtcggggacagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcaggcggcggtcgacctgttgcgcagtgag
ctgcgcccgggggacgtcgtccttgtgaaggcttccaggtcggtcggtctcgaacaggtc
gccctggctctcctcgacaccgagggcgaggtcaccggccgatga
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