Streptomyces cinereoruber: CP977_13195
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Entry
CP977_13195 CDS
T07115
Name
(GenBank) uroporphyrinogen-III synthase
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
scin
Streptomyces cinereoruber
Pathway
scin00860
Porphyrin metabolism
scin01100
Metabolic pathways
scin01110
Biosynthesis of secondary metabolites
scin01120
Microbial metabolism in diverse environments
scin01240
Biosynthesis of cofactors
Module
scin_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
scin_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scin_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scin00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CP977_13195
Enzymes [BR:
scin01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CP977_13195
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GFIT
Motif
Pfam:
HEM4
Trans_reg_C
PAS_4
Motif
Other DBs
NCBI-ProteinID:
QEV33001
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All DBs
Position
complement(2983930..2985066)
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AA seq
378 aa
AA seq
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MDEQEHGPLAGFTIGVTAARRADELIALLRRRGAAVVHGPALRIVPLADDTELLAATKEL
IDHAPDVVVATTAIGFRGWVEAADGWGYGEELLAVLRDVELLARGPKVKGAVRAAGLTES
WSPSSESMAEVLDRLLAEGVAGRRIALQLHGEPLPGFVEALTEGGAEVVGVPVYRWMPPE
DAGPLDRLLDAVLAGGVDAVTFTSAPAAASLLSRAEEKGARAELVEALRHDVLAVCVGPV
TALPLQAEGIGTYQPERFRLGPLVQVLCTELPARARVLPVAGHRVEMRGHAVLVDDALRP
VPPAGMALLGLLARRPGWVVSRADLLRALPGAGRDEHAVETAMARLRTALGTPKLIQTVV
KRGYRLALDPAADDKYDG
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atggacgagcaagaacacggccccctcgccggcttcaccatcggcgtcaccgcggcacgg
cgcgcggacgaactcatcgccctgctgcgccggcgcggcgccgccgtcgtccacgggccc
gccctgcggatcgtgccgctcgccgacgacaccgaactcctcgccgccaccaaggaactc
atcgaccacgccccggacgtcgtcgtcgccaccacggcgatcggcttccggggctgggtc
gaggccgccgacggctgggggtacggcgaggaactcctcgccgtcctgcgggacgtcgaa
ctcctcgcccgcgggccgaaggtcaagggggccgtacgggccgccggactgaccgagtcc
tggtcgccgtcctcggagtccatggccgaggtcctcgaccggctcctcgccgaaggggtg
gccggccgccggatcgcgctccagctgcacggggagccgctgcccggcttcgtggaggcg
ctgacggagggcggggccgaggtcgtcggcgtccccgtctaccgctggatgccgccggag
gacgccggtccgctcgaccggctcctcgacgcggtcctcgccgggggcgtggacgcggtg
accttcaccagcgccccggccgccgcctcgctgctctcccgcgcggaggagaagggggcg
cgggcggagctggtcgaggcgctgcggcacgacgtgctcgcggtgtgcgtggggcccgtg
accgcgctgccgctccaggcggagggcatcggcacgtaccagccggagcgcttccggctc
gggccgctcgtccaggtcctctgcaccgagctgcccgcccgcgcccgggtcctgccggtg
gccgggcaccgcgtggagatgcgcggccacgccgtcctcgtcgacgacgccctgcgcccc
gtcccgcccgccggcatggccctcctcggcctcctggcccgccgccccggctgggtcgtc
tcccgcgccgacctcctgcgcgccctgccgggcgcgggccgcgacgagcacgcggtggag
acggcgatggcccgcctccgcaccgccctcggcaccccgaagctgatccagacggtggtc
aagcggggctaccggctggccctggacccggcggcggacgacaagtacgacgggtag
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