Streptomyces cinereoruber: CP977_15300
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Entry
CP977_15300 CDS
T07115
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
scin
Streptomyces cinereoruber
Pathway
scin00860
Porphyrin metabolism
scin01100
Metabolic pathways
scin01110
Biosynthesis of secondary metabolites
scin01120
Microbial metabolism in diverse environments
scin01240
Biosynthesis of cofactors
Module
scin_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
scin_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scin_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scin00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CP977_15300
Enzymes [BR:
scin01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CP977_15300
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CP977_15300
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QEV33365
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Position
complement(3452009..3453679)
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AA seq
556 aa
AA seq
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MNPTSPTTSPLSPAFAGHGHVTFLGAGPGDPGLLTLRAVEALAGADVLIAEPEVLDVVRG
HARAGVSTPELAVVDEASTAAGVPVLRDAANLVMEAARGGRRVVRAVTGDPGLDGNAGAE
MLACAAEGIPFEVVPGVATAVGVPAYAGVPLRDAQGTDVRFVDARTADERCWSEVGASDG
TVVVSTTLDAVAAAAGELVAAGRKPDTPLTVTIAGTTTRQRTWNATLGTIAQVFKQGKVL
PSPEGHRPVIAVVGERSAPAQRDQLSWFESKPLFGWRVLVPRTKEQSASLSDQLRSYGAV
PHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAG
IKVAAVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIAT
ETLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAG
KPHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALADFGTRRRESALEAGDPV
TRPSERRPGARRRRTT
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccagcccgaccaccagccccctgtccccggccttcgcgggccacggacac
gtcaccttcctcggcgcgggaccgggcgaccccggactcctgaccctccgggccgtcgag
gccctcgcgggggcggacgtcctgatcgccgagcccgaggtcctcgacgtcgtccgcggc
cacgcgcgcgcgggggtgagcacgccggagctggcggtcgtcgacgaggcgtcaacagcc
gccggtgtccccgtgttgagggatgcggccaatcttgtcatggaggccgcgaggggcggc
aggcgggtcgtccgtgcggtgaccggcgaccccggcctcgacggcaacgcgggcgccgag
atgctcgcctgcgccgccgagggcatccccttcgaggtcgtccccggcgtcgccaccgcc
gtcggcgtccccgcgtacgccggcgtaccgctgcgcgacgcccagggcaccgacgtgcgc
ttcgtcgacgcccgcaccgccgacgagcggtgctggagcgaggtcggcgcctccgacggc
accgtcgtcgtctccaccaccctcgacgcggtggccgccgccgccggcgagctggtcgcg
gccggccgcaagccggacaccccgctcaccgtcaccatcgccggtacgaccacccgccag
cggacctggaacgccaccctcggcaccatcgcccaggtcttcaagcagggcaaggtcctc
ccctcacccgagggccaccggccggtcatagccgtggtcggcgagcgcagcgccccggcg
cagcgggaccagctgtcgtggttcgagtccaagccgctcttcggctggcgggtcctcgtg
ccgcgcaccaaggagcagtccgcctcgctctccgaccagctgcgctcgtacggcgccgtg
ccgcacgaggtcccgaccatcgccgtcgagccgccgcgcaccccccagcagatggagcgc
gcggtcaagggcctggtcaccggccgctacgagtggatcgccttcacctccgtcaacgcc
gtgaaggccgtccgcgagaagttcgaggagtacgggctcgacgcccgcgccttcgccggg
atcaaggtcgccgcggtgggcgagcagaccgccgccgccctcgtggacttcggcgtcaag
cccgacctggtgcccagcggcgagcagtccgccgccggactcctggaggactggccgccg
tacgacccggtcttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgcgacc
gagaccctggtcgcgggcctcatcgagctcgggtgggaggtggacgacgtcaccgcctac
cggaccgtacgggcctcgccgccgccggccgacacccgcgaggcgatcaagggcggcggc
ttcgacgcggtcctcttcacctcgtcctcgaccgtgcggaacctggtcggcatcgccggc
aagccgcacaacgtcaccgtcatcgcctgcatcggccccgccaccgccaagacggcggag
gagcacggcctgcgggtcgacgtcctgtcgcccgagccgtccgtccacaagctggcggag
gccctcgcggacttcggcacgcgccgccgggagtccgccctggaggcgggcgacccggtg
acgcggccgagcgagcggcgaccgggtgcgaggagacggcgcaccacctag
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