Streptomyces cinnabarinus: STRCI_004250
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Entry
STRCI_004250 CDS
T08957
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
scir
Streptomyces cinnabarinus
Pathway
scir00280
Valine, leucine and isoleucine degradation
scir00640
Propanoate metabolism
scir00785
Lipoic acid metabolism
scir01100
Metabolic pathways
scir01110
Biosynthesis of secondary metabolites
scir01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
scir00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
STRCI_004250 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
STRCI_004250 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
STRCI_004250 (pdhA)
Enzymes [BR:
scir01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
STRCI_004250 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
WAZ22942
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Position
4700296..4701447
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AA seq
383 aa
AA seq
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MTVESTAARKPRRSAGTKKSPSPKPELVQLLTPEGKRVRNAEYDKYVADITPEDLRGLYR
DMVLTRRFDAEATSLQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREHGVAWCR
GVDPTNLLGMFRGVNNGGWDPNSNNFQLYTIVIGSQTLHATGYAMGIAKDGADSAVIAYF
GDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEKQTRVPLYQRAQGYGFPGVR
VDGNDVLACLAVTKWALERARRGEGPTLVEAYTYRMGAHTTSDDPTRYRGDEERVAWEAK
DPIQRLRQFLESANHADEGFFAELETESEALGRRVREAVRAMPDPDHFAIFENVYADGHA
LVDEERAQFAAYQASFADAEGGK
NT seq
1152 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgcgcgcaagccgcgacgcagcgccgggaccaaaaagtcc
ccgagccccaagcccgagctcgttcagttgctgacgcccgagggcaagcgcgtcaggaac
gccgagtacgacaagtacgtcgccgacatcacccccgaagacctgcgcggtctgtaccgc
gacatggtgctcacccgccggttcgacgccgaggccacctcgctgcagcgtcagggcgag
ctgggcctgtgggcctcgctgctcggccaggaggccgcccagatcggttcgggccgggcc
ctgcgcgatgacgactatgtcttcccgacctaccgcgagcacggcgtcgcctggtgccgc
ggggtcgacccgaccaacctgctgggcatgttccggggtgtgaacaacggcggctgggac
ccgaacagcaacaacttccagctgtacacgatcgtcatcggctcgcagaccctgcacgcc
accggctacgccatgggcatcgccaaggacggcgcggacagcgcggtgatcgcctacttc
ggcgacggcgcctccagccagggcgatgtcgcggagtcgttcaccttctcggccgtctac
aacgcgccggtggtgttcttctgccagaacaaccagtgggcgatctccgagccgaccgag
aagcagacccgcgtcccgctctaccagcgcgcgcagggctacggcttcccgggcgtccgg
gtcgacggcaacgacgtgctggcctgtctcgcggtcaccaagtgggccctggagcgggcc
cgccgcggcgagggcccgaccctggtcgaggcgtacacctaccgcatgggcgcgcacacc
acctccgacgacccgacccgctaccggggcgacgaggagcgggtggcctgggaggccaag
gacccgatccagcgccttcgccagttcctggagtccgcaaaccacgcggacgagggattc
ttcgcggaactggagaccgagtccgaagcgttgggcaggcgagtacgcgaggcggtccgt
gccatgccggacccggaccacttcgccatcttcgagaacgtgtacgcggacgggcacgcg
ctcgtcgacgaggagcgagcccagttcgccgcctaccaggcgtcgttcgcggacgccgaa
gggggcaagtga
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