Streptomyces citrinus: V2W30_10745
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Entry
V2W30_10745 CDS
T11106
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scit Streptomyces citrinus
Pathway
scit00300
Lysine biosynthesis
scit00550
Peptidoglycan biosynthesis
scit01100
Metabolic pathways
scit01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scit00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
V2W30_10745 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
V2W30_10745 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
V2W30_10745 (murF)
Enzymes [BR:
scit01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
V2W30_10745 (murF)
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NCBI-ProteinID:
WWQ63768
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Position
complement(2299648..2301051)
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AA seq
467 aa
AA seq
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MIALSLAEIASVVGGQTYDIPDPQVRVTGPVVIDSRKVEAGSLFAAFVGERVDGHDYARD
VVDRGAAAVLASRPVGVPAIVVDDVQAALGALARHVVERLGATLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSFNNEIGLPLTALSATDETRFLVLEMGARGKGHIRYLTGLTPPKV
GVVLNVGTAHIGEFGGREQIAEAKGELVESLPAEGTAILNADDPLVRAMSSRTKARVLLF
GEAADADVRAENVRLTENGQPSFSLHTPTGCSEVTLRLYGEHHVSNALAAAAVAHDLGMS
VEEIALALSDAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALVAMGKGRRTWA
VLGHMAELGDESLAEHDAVGRLAVRLNVSKLVAIGGREASWLQLGAYNEGSWGEESVHVS
DTQAAIDLLRSELRPGDVVLVKASRSVGLESLAQALLEGFENGGDAR
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcctcagtcgtcggcgggcagacgtacgacata
ccggatccgcaggtccgggtgaccggtccggtcgtcatcgactcgcgcaaggtcgaggcc
ggcagcctgttcgccgcgttcgtcggcgagcgcgtggacggccacgactacgcgcgcgac
gtcgtggacaggggcgcggccgccgtgctggcgtcccgcccggtcggtgtgcccgccatc
gtcgtcgacgacgtccaggcggcgctcggcgcgctcgcccggcacgtcgtcgagcggctc
ggcgccaccctcgtcgcgctgaccggctcggccggcaagaccagtaccaaggacctgatc
gcccaggtgctgcggcgcaaggcgccgacggtgttcacgcccggctcgttcaacaacgag
atcggcctgccgctgaccgccctgtccgccaccgacgagacgcggttcctcgtcctggag
atgggcgcccggggcaagggccacatccgctacctgacgggcctcacccccccgaaggtc
ggcgtcgtcctgaacgtcggcaccgcccacatcggcgagttcggcggccgcgagcagatc
gcggaggcgaagggcgagctggtcgagtcgctgcccgccgagggcaccgcgatcctcaat
gcggacgatccgctcgtacgggccatgtcgtcgcgtacgaaggcgagggtgctcctcttc
ggagaggccgccgacgccgacgtccgtgccgagaatgtccggctcacggagaacggacag
ccctccttcagccttcacacacccaccgggtgcagcgaagtgaccttgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgaccttggcatgtcc
gtggaggagatcgccctcgcgctctccgacgcgggcaccctgtcccgctggcgcatggag
gtcaccgagcgcccggacggcgtcacgatcgtcaatgacgcctacaacgcgaaccccgag
tccatgcgagcggccctgcgcgcgctcgtggccatgggcaaggggcgtcgtacgtgggcg
gtgctcgggcacatggccgagctgggcgacgagtcgctggccgagcacgacgcggtcgga
cggctcgccgtccggctcaacgtcagcaagctcgtggcaatcgggggcagggaagcgtcc
tggttgcaactgggcgcctataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacacacaggcggcgatcgacctgttgcgcagcgagctgcgcccaggtgacgtcgtgctc
gtgaaggcatccaggtcggtcggcctggagagcctggcacaggcgctgctcgagggcttc
gagaacgggggcgatgcccgatga
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