Streptomyces citrinus: V2W30_22125
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Entry
V2W30_22125 CDS
T11106
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
scit Streptomyces citrinus
Pathway
scit00290
Valine, leucine and isoleucine biosynthesis
scit00770
Pantothenate and CoA biosynthesis
scit01100
Metabolic pathways
scit01110
Biosynthesis of secondary metabolites
scit01210
2-Oxocarboxylic acid metabolism
scit01230
Biosynthesis of amino acids
Module
scit_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
scit_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
scit00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
V2W30_22125 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
V2W30_22125 (ilvD)
Enzymes [BR:
scit01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
V2W30_22125 (ilvD)
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NCBI-ProteinID:
WWQ65751
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Position
4723867..4725720
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AA seq
617 aa
AA seq
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MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLAPVGRI
VSEAVTAAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICI
SNCDKITPGMLMAALRLNIPTVFVSGGPMEAGKATLVDGTVRKLDLVNAISDAVDESISD
EDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARKALYERAGAT
VVELTKRYYGEDDESVLPRNIATHAAFENAMALDIAMGGSTNTILHLLAAAREAEVDYNL
DHINAVSRRVPCLAKVAPNAAPTTTYYMEDVHRAGGIPALLGELYRGGLLNEDVHTVHSP
SIKEWLDAWDIRGGSASPEAVELWHAAPGCVRSAEAFSTSERWDTLDTDAAGGCIRDVAH
AYSKDGGLAVLKGNLAEDGCVVKTAGVDESIWTFEGPAVVCESQEEAVEKILLKQVKEGD
VVVIRYEGPKGGPGMQEMLYPTSYLKGRGLGKVCALVTDGRFSGGTSGLSIGHASPEAAA
GGTIALVEDGDRVRIDIPNRTIELLVSDEELATRREALNGVYAPKKRERKVSAALRAYAA
MATSADKGAVRDVSKLG
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagctgaggtcccgcacagtcacccacggccgcaacatggcgggcgcacgcgcc
cttatgcgcgcctccggtgtacccggtgcggacatcggccggaagccgatcatcgcggtg
gccaactccttcacggagttcgtgcccggacacacgcacctggccccggtcggccgcatc
gtcagcgaggccgtcacggccgccggcggcatcccgcgcgagttcaacacgatcgccgtc
gacgacggcatcgcgatgggccacggcggcatgctgtactccctgccctcccgcgacctg
atcgccgactcggtcgagtacatggtcgaggcgcactgcgcggacgccctgatctgcatc
tcgaactgcgacaagatcacgcccggcatgctgatggcggcgctccgcctcaacatcccg
acggtcttcgtctccggcggcccgatggaggccggcaaggccaccctggtcgacggcacg
gtccgcaagctcgacctggtcaacgcgatcagcgacgccgtcgacgagagcatctcggac
gaggacatcctccgtatcgaggagaacgcctgcccgacctgcggctcctgttccggcatg
ttcacggccaactcgatgaactgcctgaccgaggccatcggcctctcgctgccgggcaac
ggctcggtgctcgccacgcacacggcccgcaaggccctgtacgagcgcgcgggtgccacg
gtcgtcgagctgacgaagcgctactacggcgaggacgacgagagcgtcctgccgcgcaac
atcgccacgcacgcggcgttcgagaacgccatggcgctcgacatcgccatgggcggctcc
acgaacacgatcctgcacctgctggccgccgcccgtgaggccgaggtcgactacaacctc
gaccacatcaacgcggtctcgcgccgcgtcccctgcctggccaaggtcgccccgaacgcg
gcgcccacgaccacgtactacatggaggacgtgcaccgcgccggcggcatcccggccctc
ctcggcgagctctaccgcggcggcctcctgaacgaggacgtccacacggtgcacagcccc
tcgatcaaggagtggctggacgcctgggacatccgcggcggcagcgcgtcccccgaggcc
gtcgagctgtggcacgcggcccccggctgcgtccgctccgccgaggcgttctcgacgtcc
gagcgctgggacaccctcgacacggacgcggccggtggctgcatccgcgacgtcgcgcac
gcctactccaaggacggcggcctcgcggtcctcaagggcaacctggccgaggacggctgc
gtcgtgaagacggcgggcgtcgacgagtcgatctggaccttcgagggccccgcggtcgtc
tgcgagtcccaggaggaagcggtcgagaagatcctcctcaagcaggtcaaggagggtgac
gtcgtcgtcatccgctacgagggccccaagggcggccccggcatgcaggagatgctctac
ccgacctcgtacctcaagggccgcggcctcgggaaggtctgtgcgctcgtcacggacggc
cggttctccggcggcacgtcgggcctgtccatcggccacgcctcgcccgaggcggccgcc
ggtggcaccatcgcgctcgtcgaggacggcgaccgcgtccgtatcgacatcccgaaccgc
accatcgaactgctggtctccgacgaggagttggcgactcgccgcgaggctctgaacggg
gtctacgccccgaagaagcgcgagcgcaaggtctccgcggccctgcgcgcgtacgccgcg
atggcgaccagtgccgacaagggcgcggtccgcgacgtctccaagctcggctga
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