Streptomyces citrinus: V2W30_28390
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Entry
V2W30_28390 CDS
T11106
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
scit Streptomyces citrinus
Pathway
scit00290
Valine, leucine and isoleucine biosynthesis
scit00660
C5-Branched dibasic acid metabolism
scit01100
Metabolic pathways
scit01110
Biosynthesis of secondary metabolites
scit01210
2-Oxocarboxylic acid metabolism
scit01230
Biosynthesis of amino acids
Module
scit_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
scit00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
V2W30_28390 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
V2W30_28390 (leuC)
Enzymes [BR:
scit01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
V2W30_28390 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
V2W30_28390 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
DUF4946
DUF6127
Motif
Other DBs
NCBI-ProteinID:
WWQ66865
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Position
6090065..6091495
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AA seq
476 aa
AA seq
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MGSTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNAAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPEGVTA
KDLILAIIAKIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRAHAPEGADWDAAVEYWRTLKTDDDAVFDAEVFIKAEELSPFVTWGTNPGQGAPL
SANVPDPASYEDASERLAAEKALEYMGLEAGQALRDVKVDTVFVGSCTNGRIEDLRAVAD
IVKGRKVADGVRMLVVPGSARVGLQAVSEGLDQVFKDAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLAESDARTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtagcacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggccttcgtcaggccggccgccaggtgcggcgcctcgacctcaccatcgccacc
gaggatcacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcgcgc
gtgcagctggagacgctgcgcaagaacgccgcggagttcggcgtgcgcctgcactcgctg
ggcgatgtcgagcagggcgtcgtacacgtggtggggccgcagctgggcctgacccagccg
ggcaccaccgtcgtgtgcggtgactcccacacgtccacgcacggtgccttcggcgccctg
gcgttcggcatcggtacctcgcaggtcgagcacgtgctcgccacgcagacgctgccgctg
gcccgcccgaagaccatggccatcacggtcgacggcgaactgcccgagggcgtcaccgcc
aaggacctgatcctcgccatcatcgcgaagatcggcaccggcggcggccagggctacatc
ctggagtaccgcggctcggccatcgagaagctgtcgatggaagcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgccccggacgagaccacgttc
gcgtacctcaagggccgcgcccacgcccccgaaggcgccgactgggacgccgcggtggag
tactggcggacgctgaagacggacgacgacgcggttttcgacgccgaggtcttcatcaag
gccgaggagctctcccccttcgtcacctggggcaccaaccccggccagggtgcgccgctt
tcggcgaacgtccccgacccggcttcgtacgaagacgcttcggagcggctcgccgccgaa
aaggccctggaatacatggggttggaggccggtcaggcgctgcgcgacgtcaaggtcgac
accgtcttcgtaggttcgtgcaccaacggccgtatcgaggacctgcgcgccgtggccgac
atcgtcaagggccgcaaagtcgccgacggcgtacgcatgctggtcgtccccggctccgcg
cgggtgggcctccaggccgtctccgagggcctggaccaggtcttcaaggacgccggcgcc
gaatggcggcacgcgggctgctccatgtgcctcggtatgaaccccgaccaactggccccg
ggcgagcgctccgcgtccacgtcgaaccgcaacttcgagggtcgccagggcaaggggggc
cgtacccacctcgtgtcgccccaggtcgccgccgccaccgccgtgctgggccatctggcc
tccccggcggacctcgccgagtccgacgcccgtacgcccgctggagtctga
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