Streptomyces coelicolor: SCO5529
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Entry
SCO5529 CDS
T00085
Symbol
SC1C2.10
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sco
Streptomyces coelicolor
Pathway
sco00290
Valine, leucine and isoleucine biosynthesis
sco00620
Pyruvate metabolism
sco01100
Metabolic pathways
sco01110
Biosynthesis of secondary metabolites
sco01210
2-Oxocarboxylic acid metabolism
sco01230
Biosynthesis of amino acids
Module
sco_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sco00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SCO5529 (SC1C2.10)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SCO5529 (SC1C2.10)
Enzymes [BR:
sco01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SCO5529 (SC1C2.10)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
CAA19977
Kitasato:
SCO5529
UniProt:
O86511
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All DBs
Position
6023669..6025273
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AA seq
534 aa
AA seq
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MTATSELDDSFHVFDTTLRDGAQREGINLTVADKLAIARHLDDFGVGFIEGGWPGANPRD
TEFFARARQEIDFKHAQLVAFGSTRRAGANAAEDHQVKALLDSGAQVITLVAKSHDRHVE
LALRTTLDENLAMVADTVSHLKAQGRRVFVDCEHFFDGYRANPEYAKSVVRTASEAGADV
VVLCDTNGGMLPAQIQAVVATVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTA
NGYGERVGNANLFPVVAALELKYGKQVLPEGRLREMTRISHAIAEVVNLTPSTHQPYVGV
SAFAHKAGLHASAIKVDPDLYQHIDPELVGNTMRMLVSDMAGRASIELKGKELGIDLGGD
RELVGRVVERVKERELAGYTYEAADASFELLLRAEAEGRPLKYFEVESWRAITEDRPDGS
HANEATVKLWAKGERIVATAEGNGPVNALDRSLRVALEKIYPELAKLDLVDYKVRILEGV
HGTQSTTRVLISTSDGTGEWATVGVAENVIAASWQALEDAYTYGLLRAGVAPAE
NT seq
1605 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcaaccagcgaactcgacgattcgttccacgtcttcgacaccaccctgcgcgac
ggcgcgcagcgcgagggcatcaacctcacggtcgcggacaagctggccatcgcacggcac
ctggacgacttcggggtgggcttcatcgagggcggctggcccggcgccaacccgcgggac
accgagttcttcgcccgcgcccggcaggagatcgacttcaagcacgcccagctggtcgcc
ttcggctccacccgccgcgcgggcgcgaacgccgccgaggaccaccaggtcaaggcgctg
ctcgactccggcgcccaggtgatcaccctggtcgccaagtcgcacgaccggcacgtcgaa
ctggccctgcgcaccacgctggacgagaacctcgcgatggtggccgacacggtctcccac
ctgaaggcgcagggccgccgggtcttcgtcgactgcgagcacttcttcgacggctaccgc
gccaaccccgagtacgcgaagtcggtcgtgcgcaccgcctccgaggccggcgccgacgtc
gtcgtcctgtgcgacaccaacggcggcatgctcccggcgcagatccaggcggtggtcgcc
acggtgctggccgacaccggcgcccggctcggcatccacgcccaggacgacaccggctgc
gccgtcgccaacaccctcgccgccgtcgacgcgggcgcgacccacgtccagtgcacggcc
aacggctacggcgagcgggtcggcaacgccaacctgttccccgtcgtggccgcgctggag
ctgaagtacggcaagcaggtgctgcccgagggccggctgcgcgagatgacccgcatctcc
cacgccatcgccgaggtcgtcaacctcacgccctccacccaccagccctacgtgggcgtc
tccgccttcgcccacaaggccggcctgcacgcctccgcgatcaaggtcgacccggacctc
taccagcacatcgaccccgaactggtcggcaacaccatgcggatgctggtctccgacatg
gcgggacgtgcctccatcgagctgaagggcaaggagctcgggatcgacctcggcggcgac
cgcgagctggtcggccgggtcgtggagcgggtcaaggagcgcgagctggccggctacacc
tacgaggccgccgacgcgagcttcgagctgctgctgcgcgccgaggccgagggcaggccg
ctgaagtacttcgaggtcgagtcctggcgcgcgatcaccgaggaccgccccgacggcagc
cacgccaacgaggccacggtcaagctctgggccaagggcgagcgcatcgtcgccaccgcc
gagggcaacggcccggtcaacgccctggaccggtcgctgcgcgtggccctggagaagatc
taccccgagctggccaagctcgacctggtcgactacaaggtccgcatcctggagggcgtg
cacggcacccagtccaccaccagggtcctcatctccacgtccgacggcacgggggagtgg
gccacggtgggtgtcgcggagaacgtcatcgccgcctcctggcaggcgctggaggacgcg
tacacgtacgggctgctgcgggcgggggtcgcgcccgccgagtga
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