KEGG   Streptomyces coralus: QU709_28840
Entry
QU709_28840       CDS       T09650                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
scoa  Streptomyces coralus
Pathway
scoa00290  Valine, leucine and isoleucine biosynthesis
scoa00620  Pyruvate metabolism
scoa01100  Metabolic pathways
scoa01110  Biosynthesis of secondary metabolites
scoa01210  2-Oxocarboxylic acid metabolism
scoa01230  Biosynthesis of amino acids
Module
scoa_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:scoa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    QU709_28840 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    QU709_28840 (leuA)
Enzymes [BR:scoa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     QU709_28840 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: WLW55102
LinkDB
Position
6470949..6472697
AA seq 582 aa
MATSQNRQQPSTMPIHKYGQYEQVDIPDRTWPNNRITVAPRWLSTDLRDGNQALIDPMSP
ERKRRMFDQLVKMGYKEIEVGFPASGQTDFDFVRSIIEEPGAIPDDVTISVLTQAREDLI
ERTVESLKGAKRATVHLYNATAPVFRRVVFRGSKDDIKQIAVDGTRLVMEYAEKLLGPET
EFGYQYSPEIFTDTELDFALEVCEAVMDVYQPGPGREIILNLPATVERSTPSTHADRFEW
MSRNISRREHVVISVHPHNDRGTAVAAAELALMAGADRVEGCLFGQGERTGNVDLVTLGM
NLFSQGVDPQIDFSDIDEIRRTWEYCNQMEVHPRHPYVGDLVYTSFSGSHQDAIKKGFDA
MEADAAARGVTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLKNDHKLEL
PRRMQIEFSKLIQAKTDAEGGEVTGADIWAVFQDEYLPNPENPWGRIQVRNGQSTTDTDG
VDTLRVEATVDGVDTVLTGSGNGPISAFFDALQSVGVDARLLDYQEHTMSEGASAQAASY
IECAIDDKVLWGIGIDANTTRASLKAVVSAVNRAGRSVEGAR
NT seq 1749 nt   +upstreamnt  +downstreamnt
atggcgaccagccagaaccgtcagcagcccagcaccatgccgatccacaagtacggccag
tacgagcaggtcgacatccccgaccgcacctggcccaacaaccggatcaccgtcgccccc
cgctggctctccaccgacctgcgtgacggcaaccaggccctgatcgacccgatgtcgccc
gagcgcaagcgccggatgttcgaccagctggtcaagatgggctacaaggagatcgaggtc
ggcttccccgcgtcgggacagacggacttcgacttcgtacggtcgatcatcgaggagccg
ggcgcgatcccggacgacgtcaccatctccgtactgacccaggcccgcgaggacctgatc
gagcgcacggtggagtccctgaagggcgccaagcgcgccaccgtccacctgtacaacgcc
accgcgcccgtcttccgccgcgtggtcttccgcggctccaaggacgacatcaagcagatc
gccgtcgacggcacgcggctggtcatggagtacgcggagaagctgctgggtccggagacc
gagttcggctaccagtacagcccggagatcttcaccgacaccgagctggacttcgccctg
gaggtctgcgaggcggtgatggacgtctaccagcccggcccgggccgcgagatcatcctc
aacctgcccgccacggtggagcgttcgacgccgtccacgcacgcggaccgcttcgagtgg
atgagccgcaacatctcccgccgcgagcacgtcgtcatctccgtccacccgcacaacgac
cgcggtacggccgtcgccgccgccgagctggcgctgatggccggcgccgaccgcgtcgag
ggctgcctgttcggacagggcgagcgcaccggcaacgtcgacctggtcaccctgggcatg
aacctgttctcgcagggcgtcgacccgcagatcgacttctccgacatcgacgagatccgt
cgtacgtgggagtactgcaaccagatggaggtccacccgcgccacccgtacgtgggcgac
ctggtctacacgtccttctccggctcccaccaggacgccatcaagaagggcttcgacgcg
atggaggccgacgcggcggctcgcggggtcaccgtggacgacatcgagtgggcggtgccg
tatctgcccatcgaccccaaggacgtcggccgttcgtacgaggccgtcatccgcgtcaac
tcgcagtccggcaagggcgggatcgcgtacgtcctgaagaacgaccacaagctggaactg
ccccgccggatgcagatcgagttctcgaagctcatccaggcgaagacggacgcggagggc
ggcgaggtcaccggggcggacatctgggccgtcttccaggacgagtacctgccgaacccc
gagaacccgtgggggcgtatccaggtccgcaacggtcagtcgacgaccgacacggacggg
gtggacacgctgcgggtcgaggcgacggtggacggcgtcgacacggtgctgacggggtcg
ggcaatggtccgatctcggccttcttcgacgcgctgcagtccgtcggtgtggatgctcgg
ctgctggactatcaggagcacacgatgagcgagggggcttctgcgcaggccgcgtcctac
atcgagtgtgcgatcgacgacaaggtgctgtggggtatcgggatcgatgcgaacacgact
cgggcttcgctgaaggcggtcgtctccgccgtcaaccgggcggggcgctctgtcgagggg
gcgcggtag

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