Streptomyces coralus: QU709_32345
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Entry
QU709_32345 CDS
T09650
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scoa
Streptomyces coralus
Pathway
scoa00300
Lysine biosynthesis
scoa00550
Peptidoglycan biosynthesis
scoa01100
Metabolic pathways
scoa01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scoa00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
QU709_32345 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
QU709_32345 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
QU709_32345 (murF)
Enzymes [BR:
scoa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
QU709_32345 (murF)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF2126
DHHA1
Motif
Other DBs
NCBI-ProteinID:
WLW55744
LinkDB
All DBs
Position
7240523..7241944
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AA seq
473 aa
AA seq
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MIALSLAEIAAVVGGQTHDIPDPSAEVTGPVVRDSREAGPGTLFAAFAGERVDGHDFARQ
VVEAGAVAVLASRPVGVPAIVVEDVQSALGALARHVVRQLGATLVALTGSAGKTSTKDLI
AQVLQRKAPTVWTPGSLNNEIGLPLTALSATEETRFLVLEMGARGIGHIRYLAGLTPPKI
GLVLNVGSAHIGEFGGREQIAQAKGELVEALPEDGTAVLNADDPLVRAMASRTKAKVILF
GESGEADVRAENVRLTDSGQPAFLLRTPSGASEVTMRLYGEHHVSNALAAAAVAHELGMS
AEEIATALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGKATQARG
GRTWAVLGKMAELGDEALAEHDAVGRLAVRLNVGKLVAVGGREASWLQLGAYNEGSWGEE
SVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLESVAQALVETGAEGEVSAR
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcagcagtcgtcggcgggcagacgcatgacata
ccggatccgtcggccgaggtcaccggaccggtcgtccgggactcccgcgaggcgggaccg
ggcaccctgttcgccgcgttcgccggtgaacgcgtcgacggccacgacttcgcccggcag
gtcgtcgaggcgggcgcggtcgccgtgctggcctcccgcccggtcggagtgcccgcgatc
gtcgtcgaggacgtccagagcgccctcggtgccctcgcacgtcatgtcgtacgacagctc
ggcgcgaccctcgtggcgctcaccgggtccgccggcaagaccagcaccaaggacctgatc
gcgcaggtgctccagcgcaaggcgccgacggtgtggacgcccggctcgctcaacaacgag
atcggactgccgctgaccgccctgtccgccaccgaggagacgcggttcctcgtgctggag
atgggcgcccgcggcatcggccacatccgctacctcgccggcctgacgcccccgaagatc
ggcctcgtgctcaacgtcggctccgcccacatcggcgagttcggcggccgcgagcagatc
gcgcaggccaagggcgaactcgtggaggccctcccggaggacggcaccgcggtcctcaac
gcggacgaccccctcgtacgggccatggcctcccgtacgaaggcgaaggtgatccttttc
ggagagtccggcgaagcggacgtacgcgccgagaacgtgagactcacggacagcggacag
cccgccttcctgcttcgcacaccctccggtgcaagcgaagtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gcggaagagatcgccaccgcgctctccgaggcgggctccctctcccgctggcgtatggag
gtcaccgagcgcccggacggcgtgaccatcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgccttgcgcgcgctcgcggccatgggcaaggccactcaggcaaggggg
ggtcggacctgggcggtgctcggcaagatggccgagctcggggacgaggcgctcgccgag
cacgacgcggtcggacggctggccgtccggctcaatgtcggcaagctcgtcgcggtcggg
ggcagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggcggtcgacctgttgcgcagcgagttgcgcccg
ggagacgtcgtactcgtgaaggcgtcccggtcggtcggactcgagagcgtggcgcaggcg
ctcgtcgagaccggtgccgagggtgaggtttccgcccgatga
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