Streptomyces coeruleorubidus: CP976_12085
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Entry
CP976_12085 CDS
T07302
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scoe
Streptomyces coeruleorubidus
Pathway
scoe00300
Lysine biosynthesis
scoe00550
Peptidoglycan biosynthesis
scoe01100
Metabolic pathways
scoe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scoe00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CP976_12085
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CP976_12085
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CP976_12085
Enzymes [BR:
scoe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CP976_12085
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
QEV24830
UniProt:
A0A5J6I2M5
LinkDB
All DBs
Position
complement(2592246..2593652)
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AA seq
468 aa
AA seq
DB search
MIALSLAEIAEVVGGQTHDIPDPTVQVTGPVVRDSREAGPGSLFVAFAGERVDGHDFAAA
VVEAGAVAVLGTRPVGVPAIVVDDVQAALGALARHVVRRLGATLVALTGSAGKTSTKDLI
AQVLQRKAPTVFTPGSLNNEIGLPLTALSATEDTRFLVLEMGARGIGHISYLTGLTPPKV
GLVLNVGSAHIGEFGGREQIAQAKGELVESLPEDGTAVLNADDPYVRAMASRTKAKVIFF
GESDEADVRAENVRLTDTGQPAFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHELGMS
ADEIAVALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAIGKGRRTWA
VLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREAAWLQLGAYNEGSWGEESVHVS
DAQAAVDLLRSELRPGDVVLVKASRSVGLESVAQALLESGAEGEVSAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagaagtcgtcggcgggcagacgcacgacata
ccggatccgaccgtccaggtcaccggcccggtcgtccgggactcccgcgaggcggggccg
ggcagcctgttcgtcgccttcgccggcgagcgcgtggacggccacgacttcgcggccgcg
gtcgtcgaggcgggagcggtggccgtgctcggcacccggcccgtcggcgtgcccgcgatc
gtcgtggacgacgtccaggccgcgctcggcgccctcgcgcggcacgtcgtacgacgtctc
ggcgccaccctcgtcgctctcaccggctcggcgggcaagaccagcaccaaggacctgatc
gcgcaggtgctccagcgcaaggcgcccacggtcttcacgcccggctcgctcaacaacgag
atcgggctgccgctgaccgcgctcagcgccaccgaggacacccggttcctcgtcctggag
atgggggcccgcggtatcgggcacatctcctacctcacgggtctcacgcccccgaaggtc
ggcctcgtcctgaacgtcggcagcgcccacatcggcgagttcggcggccgcgagcagatc
gcgcaggccaagggcgaactcgtcgagtccctcccggaggacgggacggccgtcctcaac
gcggacgacccctacgtgcgggccatggcctcccgtacgaaggcgaaggtgatctttttc
ggagagtccgacgaagcggacgttcgcgccgagaacgtgcgactcacggacacgggacag
cccgcattcaggcttcacacaccctccggtgcaagcgatgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgagttgggcatgtcc
gcagacgagatcgccgtcgcgctctccgaggcgggctccctctcccgctggcggatggag
gtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgctctgcgcgcgctcgcggcgatcggcaaggggcgccgtacgtgggcg
gtgctcggcaagatggccgagctcggggacgaggctctcgccgagcacgacgcggtcgga
cggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcggtggcagggaagccgcc
tggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcggtcgacctgttgcgcagcgagttgcgcccgggagacgtcgtactc
gtgaaggcgtcccgttcggtcggcctcgagagcgtggcgcaggcgctgctcgagtccggt
gccgagggtgaggtttccgcccgatga
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