Streptococcus parasanguinis ATCC 15912: HMPREF0833_10158
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Entry
HMPREF0833_10158 CDS
T01545
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scp
Streptococcus parasanguinis ATCC 15912
Pathway
scp00300
Lysine biosynthesis
scp00550
Peptidoglycan biosynthesis
scp01100
Metabolic pathways
scp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HMPREF0833_10158 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HMPREF0833_10158 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HMPREF0833_10158 (murF)
Enzymes [BR:
scp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HMPREF0833_10158 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Cellulase
Motif
Other DBs
NCBI-ProteinID:
AEH55189
UniProt:
F8DFB4
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All DBs
Position
155326..156696
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AA seq
456 aa
AA seq
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MNLTLHEVAHLVHAKNDISQFEDVALVKPEFDSRLIGPGDLFVPLKGARDGHDFIETAFE
NGAVATFSEKVVEGHPYILVEDVLSAFQTLAAAYLQKTKVDVFAVTGSNGKTTTKDMLAQ
LLSTTYLTYKTQGNYNNEIGLPYTVLHMPEGTDKLVLEMGQDHLGDIHLLSELAHPKAAI
VTLIGEAHLEFFKDRSEIAKGKLQIADGMPEGGLLVVPADPIVDAYLPENQTVVRFGPDE
EIFITELIERKDSLTFRANFLEEAIDLPVTGKYNATNAMIAAYVALKEGVSEAAIRDSFE
TLQLTRNRTEWKKASNGADILSDVYNANPTAMRLILETFSTIPANPNGRKLAVLADMKEL
GEQSVDLHNQMILSLSPDVLDTVIFYGQDIAGLAQLASQMFPLGHVYYFKKTAEEDQFED
MVKQVKESLKEQDQILIKGSNSMNLGKLVEELENGK
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgaatctcacattacatgaagttgctcatctagtacatgcaaaaaatgatatcagccaa
tttgaagatgtggccctcgtcaagccggaatttgacagccgtttgattgggcctggagac
ctgtttgttcctttaaagggagcgcgtgatggtcatgattttattgagactgcttttgaa
aacggagccgtagccactttttcagagaaagtggtagaaggccacccttatattttggtg
gaagatgtgctgagtgcttttcaaacattagctgcagcctatcttcaaaagacaaaagtg
gatgtttttgcagtgacggggtcaaatggtaaaaccaccacaaaagatatgttggcacag
cttttgtccaccacctacctaacctataaaacacagggaaactataataacgaaattggt
cttccttatacggttttgcatatgccagaagggacagacaaactcgtccttgaaatgggg
caagaccatctaggagatatccatctcttgtcagaactggcgcatccaaaagctgctatt
gtcaccttgattggggaagcccatttggaattctttaaagatcgaagtgagatcgcaaaa
ggaaaactccagattgcggacgggatgccagaaggtggccttctggtagttccagctgat
ccgatcgtcgatgcctaccttcctgaaaatcaaacagtcgtccgctttgggccagacgag
gagatttttattactgagttaatcgagcgaaaggatagcttaactttccgagctaatttc
ttagaagaagcgattgatcttccagtaacaggaaaatataatgcgaccaatgccatgatt
gcagcttatgttgccttgaaagaaggagtgagtgaagctgcgattcgtgatagtttcgaa
accttgcaattaactcgcaaccggacagaatggaagaaggcaagtaacggagcagatatc
ttatccgatgtctacaatgccaacccaacggccatgcgcctaatcttagaaactttctcg
actattcctgccaatccaaatggtcgaaaattggccgtcctggcagatatgaaagaacta
ggggagcaatcggtagatctgcacaaccaaatgattctcagcctctcgccagatgttttg
gatacggttattttctatggtcaagacattgcgggattggctcagttagcgagtcagatg
ttcccactcggacatgtctattatttcaagaagacagctgaggaagatcagtttgaggac
atggtcaaacaagtcaaggaaagcttgaaagagcaagaccaaatccttatcaagggaagc
aattccatgaatttgggcaaattggtagaggaattggagaatggtaagtaa
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