Streptomyces cyaneogriseus: TU94_12880
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Entry
TU94_12880 CDS
T03687
Name
(GenBank) bifunctional uroporphyrinogen-III synthetase/response regulator domain protein
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
scw
Streptomyces cyaneogriseus
Pathway
scw00860
Porphyrin metabolism
scw01100
Metabolic pathways
scw01110
Biosynthesis of secondary metabolites
scw01120
Microbial metabolism in diverse environments
scw01240
Biosynthesis of cofactors
Module
scw_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scw_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
TU94_12880
Enzymes [BR:
scw01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
TU94_12880
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Gene cluster
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Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
AJP02243
UniProt:
A0A0C5FX15
LinkDB
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Position
complement(3120081..3121232)
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AA seq
383 aa
AA seq
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MDDEQQRPDHGPLAGFTVGVTAARRADELGALLQRRGAAVLHAPALRIVPLADDSELLAA
TKQLIDQAPDVVVATTAIGFRGWVEAADGWGLGEALLDRLRSVELLARGPKVKGAVRAAG
LTEQWSPSSESMAEVLDRLLEEGVDGRRIAVQLHGEPLPGFVEALRAGGAEVVGVPVYRW
LPPEDLGPVDRLLDAAVSRGVDALTFTSAPAAASLLNRAEERGLLPALLTALGHDVLPAC
VGPVTALPLQAHGVDTVQPERFRLGPLVQLLCRELPARARALPIAGHRLEIRGHAVLVDD
ELRPVPPAGMALLRALSRRPGWVVPRAELLRALPGAGRDEHAVETAMARLRTALGAPKLI
QTVVKRGYRLALDPAADAKYADA
NT seq
1152 nt
NT seq
+upstream
nt +downstream
nt
atggacgacgaacagcagcgacccgaccacggccccctggccggcttcaccgtaggggtg
accgccgcccgccgggccgacgaactgggggccctcctccagcggcgcggagccgccgtc
ctgcacgcccccgccctgcggatcgtgcccctcgccgacgacagcgagctcctcgccgcc
accaagcagctcatcgaccaggcgcccgacgtggtcgtggccaccaccgcgatcgggttc
cggggctgggtcgaggccgccgacggatgggggctgggcgaggcactgctggaccggctg
cggtccgtggagctgctggcgcgcggccccaaggtcaagggcgcggtgcgggccgccggg
ctgaccgaacagtggtcgccgtcgtccgagtccatggccgaggtgctcgaccggctgctg
gaggagggcgtcgacggccgccggatcgccgtccagctgcacggcgagccgctgcccggg
ttcgtggaggcgctgcgggcgggcggcgccgaggtcgtcggggtgccggtctaccggtgg
ctgccgccggaggacctcggccccgtcgaccggctgctggacgccgccgtctcccgcggt
gtggacgccctgaccttcaccagcgcgcccgccgccgcgtccctgctgaaccgcgccgag
gagcgcggcctgctgcccgcgctgctcaccgccctcggtcatgacgtcctgccggcctgc
gtcggcccggtcaccgcgctgccgctccaggcgcacggcgtggacaccgtccagcccgag
cgcttccgcctcggccccctcgtccaactgctgtgccgggaactcccggcccgcgcacgg
gcgttgcccatcgccgggcaccggctggagatccgcgggcacgccgtgctggtcgacgac
gagctcaggcccgtaccccccgccgggatggcgctgctgcgggccctgtcccggcggccc
ggctgggtcgtgccccgcgcggagctgctgcgcgcgctgccgggcgccgggcgcgacgag
cacgcggtggagacggcgatggcccggctgcgcacggccctcggggcgccgaagctgatc
cagaccgtcgtcaagcgcggctaccggctggcgctggacccggccgccgacgccaagtac
gccgacgcctga
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