Streptomyces cyaneogriseus: TU94_18650
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Entry
TU94_18650 CDS
T03687
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
scw
Streptomyces cyaneogriseus
Pathway
scw00860
Porphyrin metabolism
scw01100
Metabolic pathways
scw01110
Biosynthesis of secondary metabolites
scw01120
Microbial metabolism in diverse environments
scw01240
Biosynthesis of cofactors
Module
scw_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scw_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
scw_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
TU94_18650
Enzymes [BR:
scw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
TU94_18650
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
TU94_18650
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
BiPBP_C
Motif
Other DBs
NCBI-ProteinID:
AJP03195
UniProt:
A0A0C5G3N4
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Position
4426832..4428562
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AA seq
576 aa
AA seq
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MSPTTLPAGPEHGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHEVLDVVREHARQGV
AEVHTDADPSAEPAGSSSGPHPGTGTPQLTVVDGTSTTVGVPAVRDAAHLVMEAARGGRR
VVRAVSGDPGLDADAAEEMLACAAAGVPFEVVPGIATAVGVPAYAGVPLRDAEGADVRFV
DARTASDRCWTEVGASDGTVVVSTTLDSVAAAAGELVAAGRKPDTPLTVTVAGTTTRQRT
WTATLGTIAQTLKQAKVLPSPEGGRPVIAVVGERGAAARREKLSWFESKPLFGWKVLVPR
TKEQAASLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVK
AVREKFEEYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYD
PVFDPIDRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFD
AVLFTSSSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEAL
ADFGMKRRLAALEAGDPVTRPSERRPGARRRRSTTT
NT seq
1731 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacccttcccgccggtccggaacacgggcacgtcaccttcctgggtgcc
ggacccggagatccgggactgctgaccctgcgcgctgtggaggcgctggcgaacgcggac
gtcctcgtcgccgagcacgaggtgctcgacgtcgtccgcgagcacgccaggcagggcgtc
gccgaagtgcacacggacgccgatccttcggcggaaccggccggctcttcctccggaccg
catccgggcacaggcacgcctcagctgacggtagttgacggcacgtcaaccaccgtgggc
gttcccgctgtgcgggatgccgcacatcttgtcatggaggccgcgcggggcggcaggcgg
gtcgtccgtgcggtgtccggggatcccggactcgacgcggacgccgccgaggagatgctg
gcctgcgccgccgccggggtgcccttcgaggtcgtcccgggcatcgcgacggccgtcggc
gtgccggcgtacgccggtgtgccgctgcgcgacgccgagggcgccgacgtgcggttcgtg
gacgcccgtaccgcctccgaccgctgctggacggaggtgggcgcctccgacggcacggtc
gtggtctccacgacgctcgactcggtcgccgcggcggccggcgagctggtggcggcgggc
cgcaagccggacaccccgctgaccgtgaccgtcgccggtacgaccacccggcagcggacc
tggaccgccacgctcggcaccatcgcgcagacgctgaagcaggccaaggtgctgccgtcg
ccggagggcggccggccggtgatagccgtggtcggtgagcgcggtgccgccgcccggcgc
gagaagctgtcgtggttcgagtccaagccgctgttcggctggaaggtgctcgtgccgcgt
acgaaggagcaggcggcctcgctctccgaccagttgcggtcctacggggccgtgccgcac
gaggtgccgacgatcgccgtcgagccgccgcgcaccccgcagcagatggagcgcgcggtc
aagggcctggtgaccggccggtacgagtggatcgcgttcacctcggtcaacgcggtcaag
gccgtgcgggagaagttcgaggagtacgggctggacgcccgcgccttcgcgggcatcaag
gtcgccgcggtcggcgagcagaccgcgaaggcgctgatcgccttcggtgtgaagccggat
ctggtgccgagcggggagcagtccgcggccggcctgctggaggactggccgccgtacgac
ccggtgttcgacccgatcgaccgggtcttcctgccgcgcgccgacatcgccaccgagacg
ctcgtcgccgggctgatcgagctgggctgggaggtcgacgacgtcaccgcctaccggacg
gtgcgcgcctcgccgccgcccgccgagacgcgggaagcgatcaagggcggtggtttcgac
gcggtgctgttcacgtcgtcctccaccgtgcggaacctcgtcggcatcgcgggcaagccg
cacaacgtgacggtgatcgcctgcatcggcccggccaccgccaagacggcggaggagcac
ggactgcgcgtcgacgtcatggcgcccgagccgtccgtgcacaagctggccgaggcgctg
gccgacttcggcatgaagcggcggctggcggccctcgaggccggcgacccggtgacccgg
ccgagcgagcggcgtccgggcgcgcgcaggcggcggtcgacgacgacgtga
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