Streptomyces sp. CdTB01: AS200_32465
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Entry
AS200_32465 CDS
T04240
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scx
Streptomyces sp. CdTB01
Pathway
scx00300
Lysine biosynthesis
scx00550
Peptidoglycan biosynthesis
scx01100
Metabolic pathways
scx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AS200_32465
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AS200_32465
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AS200_32465
Enzymes [BR:
scx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AS200_32465
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DHHA1
Motif
Other DBs
NCBI-ProteinID:
ALV36239
UniProt:
A0A0U3FCN3
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All DBs
Position
7297448..7298854
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AA seq
468 aa
AA seq
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MIALSLAEIAEVVGGQTHDIPDPSVQVTAPVVRDSRQVEPGSLFVAFVGERVDGHDYARQ
VVEAGAVAVLASRPVGVPAIVVDDVQSALGALARHVVRRLGATLVALTGSAGKTSTKDLI
AQVLQRKAPTVFTPGSLNNEIGLPLTALSATEETKFLVLEMGARGIGHIRYLTELTPPRI
GLVLNVGSAHIGEFGGREQIAQAKGELVEALPEDGAAILNADDPFVRAMASRTKARVVFF
GESDEADVRAENVRLTDTGQPAFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHELGMS
AEEIATALSEADSLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALVAMGKGRRTWA
VLGKMAELGDEALAEHDAVGRLAVRLNVGKLVAVGGREASWLQLGAYNEGSWGEESVHVS
DAQAAIDLLRSELRPGDVVLVKASRSVGLESVAQALLETGAAGGADAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcagaagtcgtcggcgggcagacgcacgacata
ccggatccgtccgtccaggtcaccgctccggtcgtccgggactcccgccaggtggagccc
ggcagcctgttcgtcgccttcgtcggcgaacgcgtcgacggccacgactacgcccggcag
gtcgtggaggcgggcgcggtcgccgtcctcgcgtcccggcccgtcggcgtccccgcgatc
gtcgtcgacgacgtccagagcgccctcggcgccctcgcgcggcacgtcgtacgacggctc
ggcgcgaccctcgtggccctcaccggctcggcgggcaagaccagcaccaaggacctgatc
gcccaggtcctccagcgcaaggcgccgacggtgttcacgcccggctcgctcaacaacgag
atcggcctgccgctgaccgccctgtccgccaccgaggagacgaagttcctcgtgctggag
atgggcgcccgcggcatcggccacatccgctacctcaccgagctgaccccgccgcggatc
ggcctcgtgctcaacgtcggcagcgcccacatcggggagttcggcggccgcgagcagatc
gcgcaggccaagggcgaactcgtggaggccctgccggaggacggcgccgcgatcctcaac
gcggacgaccccttcgtacgggcgatggcgtcccgcacgaaggccagggtggtcttcttc
ggcgagagcgacgaagcggacgtacgggccgagaacgtgcgactcacggacacgggacag
cccgcgttcaggctccacacaccctccggtgcaagcgacgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gcggaagagatcgccaccgcgctctccgaggcggactccctctcccgctggcgtatggag
gtcaccgagcgaccggacggcgtgaccatcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgccctgcgcgcgctcgtggccatgggcaagggacgccggacctgggcg
gtgctcggcaagatggccgagctcggggacgaggcgctcgccgagcacgacgcggtcgga
cggctcgccgtccggctcaatgtcggcaagctcgtcgcggtcgggggcagggaagcgtcc
tggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcgatcgacctgttgcgcagcgagttgcgcccgggggacgtcgtgctc
gtgaaggcgtcccggtcggtggggctcgagagcgtggcgcaggcgctgctcgagaccggt
gccgcgggtggggctgatgcccgatga
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