KEGG   Streptomyces sp. CdTB01: AS200_35850
Entry
AS200_35850       CDS       T04240                                 
Name
(GenBank) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
scx  Streptomyces sp. CdTB01
Pathway
scx00860  Porphyrin metabolism
scx01100  Metabolic pathways
scx01110  Biosynthesis of secondary metabolites
scx01120  Microbial metabolism in diverse environments
scx01240  Biosynthesis of cofactors
Module
scx_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:scx00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    AS200_35850
Enzymes [BR:scx01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     AS200_35850
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     AS200_35850
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     AS200_35850
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 2-Hacid_dh_C Radical_SAM
Other DBs
NCBI-ProteinID: ALV36855
UniProt: A0A0U3NJZ7
LinkDB
Position
8040872..8042104
AA seq 410 aa
MAEHPAYPVGLRLTGRKVVVLGGGQVAQRRLPALVAAGADVLLVSPEATPSVEAMADAGE
ITWERRGYAEGDLADAWYALIATSDAEANVRASAEAEAHRVWCVRSDDADAATAWTPATG
TSEGVTVAVLTSRARGRDPRHTAAIRDAVVEGLRDGTLVAPHFRTRTPGVALVGGGPGDP
DLITVRGRRLLAEADVVITDHLGPRDLLAELSPGVEVIDAAKLPFGRFMAQEAINNALIE
HAKQGRSVVRLKGGDPFVYGRGMEEVNALAEAGIPCTVVPGISSSISVPGAAGIPVTHRG
VAHEFTVVSGHIAPDDERSLVDWPSLAKLTGTLVILMGVKTIGKVAETLIAHGKSPDTPV
ALIQEGTTAAQRRVDATLATVAETVVAQEVRSPAVIVVGAVVNVGPETSA
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggccgaacaccccgcctatcccgtaggcctccgcctcaccggccgcaaagtggtcgtc
ctcggcggcggccaggtcgcccagcgccgcctcccggccctggtcgcggcaggcgcggac
gtcctgctcgtctcgcccgaggcgactccctccgtcgaggcgatggcggatgccggcgag
atcacctgggagcggcgggggtacgccgagggggacctggcggacgcctggtacgccctg
atcgccaccagtgacgccgaggcgaacgtccgtgcctcggccgaggcggaggcccaccgg
gtgtggtgcgtgcgctccgacgacgccgacgccgccaccgcctggaccccggccaccggc
accagcgagggcgtgacggtcgccgtcctcaccagccgcgcccgcggccgcgacccccgg
cacaccgccgccatccgcgacgcggtcgtcgagggcctgcgcgacggcaccctggtcgcc
ccgcacttccggacccgcacccccggcgtcgccctggtcggtggcggccccggcgacccg
gacctgatcaccgtgcgcggccgccgtctgctcgccgaggccgacgtcgtcatcaccgac
cacctgggcccccgcgacctgctcgccgagctgtccccgggcgtcgaggtgatcgacgcg
gcgaagctgccgttcgggcgcttcatggcccaggaggccatcaacaacgcgctgatcgaa
cacgccaagcagggcaggtcggtcgtccggctcaagggcggcgacccgttcgtctacggc
cgcgggatggaggaggtcaacgcgctcgcggaggccggcatcccgtgcacggtcgtgccc
ggcatctccagctcgatctcggtgccgggcgcggccggcatcccggtcacccaccgcggt
gtcgcacacgagttcaccgtggtcagcgggcacatcgcccctgacgacgagcgttccctc
gtcgactggccctcgctcgccaagctgaccgggacgctcgtgatcctcatgggcgtgaag
acgatcggcaaggtcgccgagacgctcatcgcgcacggcaagtcgcccgacaccccggtc
gcgctgatccaggagggcacgacggccgcccagcggcgcgtcgacgccaccctcgccacg
gtcgccgagaccgtcgtcgcgcaggaggtcaggtcgccggccgtcatcgtcgtcggcgcc
gtcgtgaacgtgggcccggagacctcggcgtaa

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