Streptomyces cyaneofuscatus: R2B67_02175
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Entry
R2B67_02175 CDS
T09646
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
scye
Streptomyces cyaneofuscatus
Pathway
scye00270
Cysteine and methionine metabolism
scye00480
Glutathione metabolism
scye01100
Metabolic pathways
scye01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
scye00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
R2B67_02175 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
R2B67_02175 (egtA)
Enzymes [BR:
scye01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
R2B67_02175 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
WOP07413
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All DBs
Position
530873..532219
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AA seq
448 aa
AA seq
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MSSDTPGGPGAHPDHATLDEGAAQDLLRGICFKTGPPRIVGVELEWLIHDQENPAVPVAQ
ERLDSAVAALRELPLSAALTFEPGGQLELSSQPAGSLMECVGTTAADLAAVRASLGRDGL
APVGLGVDPWQTPHRRLREPRYDAMEAALDRAGPSGRAMMCTSASVQVCLDAGEEEPGPL
GYRRRWQLTHLLGAVLVAAFANSPFRQGRPTGWKSSRQALWADLDPVRTLAPGSGLPPRE
AWAAHVLDTTVMCVRREEGPWDVPEGLTFREWIRTGAPRPPVRADLDYHITTLFPPVRPR
GHLELRMIDAQSGADGWLVPLAVATALYDDPEAAETVYRTVKPLAESAGSAPAPRNPLWT
TAAREGLADPELRAAATVCFDTALTALDRMGADKAVRDTVAAFNDRYAARGRCPADDLLD
SGVLTDPVRPTGLIGSTDDPHTGRVASA
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcggacacacctggcggccccggcgcacacccggatcacgccaccctcgacgag
ggtgcggcccaggatttactgcgcggcatatgtttcaagacgggtccccctcgcatcgtg
ggggtggaactcgaatggctcatccatgaccaggagaatcccgccgttccagtggcccag
gagcggctggacagcgccgtcgcggccctccgggagctgcccctgagcgccgcactgacg
ttcgagccgggcgggcagctggagctcagctcccagccggccggctccctgatggagtgc
gtcgggacgaccgcggcggacctggccgccgtccgcgcctcgctcggccgggacgggctc
gccccggtcggcctcggcgtggacccgtggcagacgccgcaccgcaggctgcgcgagccc
cggtacgacgcgatggaggcggcgctcgaccgggcgggcccgtccgggcgggcgatgatg
tgcacctccgcctccgtgcaggtctgcctggacgcgggcgaggaggagccgggcccgctc
ggctaccggcggcgctggcagctcacccatctgctcggtgccgtcctggtggccgcgttc
gccaattcgccgttccggcagggccgcccgaccggctggaagtcctcccggcaggccttg
tgggccgatctcgacccggtacggacgctggcgccgggcagcgggcttcccccgcgtgag
gcgtgggccgcgcatgtgctggacacgaccgtgatgtgcgtccgccgcgaggagggcccc
tgggacgtgcccgagggcctcaccttccgcgagtggatccgtaccggcgcgccccggccg
ccggtacgggccgatctcgactaccacatcaccaccctgttcccgccggtccggccgcgc
gggcacctcgaactgcgcatgatcgacgcgcagagcggcgcggacgggtggctggtgccg
ctcgccgtcgccaccgccctgtacgacgacccggaggccgccgagaccgtgtaccgcacc
gtgaagcccctggccgagtcggcgggatccgctcccgcgccgcgcaacccgctctggacg
acggccgcccgcgagggcctcgccgatccggagctgcgggcggcggccacggtctgcttc
gacacggcgctcaccgcgctcgaccggatgggcgccgacaaggcggtacgggacaccgtg
gcggccttcaacgaccggtatgcggcccggggccgatgtccggccgacgatctgctcgat
tcaggcgttctcaccgatccggtccggccgacgggcctcatcggctccacggacgacccg
cacaccggaagggtggcctcagcatga
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