Streptomyces cyaneofuscatus: R2B67_08400
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Entry
R2B67_08400 CDS
T09646
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
scye
Streptomyces cyaneofuscatus
Pathway
scye00290
Valine, leucine and isoleucine biosynthesis
scye00660
C5-Branched dibasic acid metabolism
scye01100
Metabolic pathways
scye01110
Biosynthesis of secondary metabolites
scye01210
2-Oxocarboxylic acid metabolism
scye01230
Biosynthesis of amino acids
Module
scye_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
scye00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
R2B67_08400 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
R2B67_08400 (leuC)
Enzymes [BR:
scye01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
R2B67_08400 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
R2B67_08400 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
WOP08582
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Position
complement(2033232..2034659)
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AA seq
475 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPEDVTA
KDLILAIITRIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGRDAAPRGEEWDAAVAYWKTLRSDDDAVFDAEVVIDATELAPFVTWGTNPGQGAPL
SANVPDPASYEDASERNAAEKALEYMGLTAGQPLRDINVDTVFVGSCTNGRIEDLRNAAA
ILDGRKVADGVRMLVVPGSVRVALQAVSEGLDKVFTGAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDTRTPAGVA
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggaaaaggtctgggacgaccatgtcgtccggcgcgcggagggc
gagcccgaccttctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggtctgcgccaggccggacgtccggtgcgacgcctcgacctcaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcccga
gcccagctggagaccctgcgcaagaactgcgcggagttcggcgtgcggctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtggtcggcccgcagctgggcctgacccagccc
ggcaccaccgtggtctgcggtgactcccacacctccacgcacggggcgttcggcgcgctg
gcgttcggcatcggcaccagccaggtggagcacgtcctggccacccagacgctgccgctg
gcccgcccgaagaccatggccatcacggtcgacggcgagctgcccgaggacgtcaccgcc
aaggacctgatcctggcgatcatcacccggatcggcaccggcggcggccagggctacatc
ctcgaataccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggtgcccgcgcgggcatgatcgccccggacgagaccaccttc
gcctatctggagggccgcgacgccgcccccaggggcgaggagtgggacgcagccgtcgcg
tactggaagacgctgcgctcggacgacgacgcggtgttcgacgccgaggtcgtcatcgac
gccaccgagctggccccgttcgtcacctggggcaccaaccccggccagggcgcgccgctc
tccgcgaacgtccccgaccccgcttcgtacgaggacgcctcggagcgcaacgccgccgaa
aaggccctggagtacatggggttgaccgccgggcagccgctgcgcgacatcaacgtggac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgcaacgccgccgcc
atcctggacggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctccgtc
cgggtcgccctccaggccgtctccgagggcctggacaaggtcttcaccggggccggcgcc
gaatggcggcacgcgggttgctcgatgtgcctcggcatgaaccccgaccagctggccccc
ggcgagcgctccgcctccacctcgaaccgcaacttcgagggccggcagggcaagggcggc
cgcacccacctggtctcgccccaggtcgccgccgccaccgccgtgctgggccatctggcc
tcgcccgccgacctgtccgacacccgtacccccgccggagtcgcatag
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