Streptomyces cyaneofuscatus: R2B67_18330
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Entry
R2B67_18330 CDS
T09646
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
scye
Streptomyces cyaneofuscatus
Pathway
scye00280
Valine, leucine and isoleucine degradation
scye00640
Propanoate metabolism
scye00785
Lipoic acid metabolism
scye01100
Metabolic pathways
scye01110
Biosynthesis of secondary metabolites
scye01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
scye00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
R2B67_18330 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
R2B67_18330 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R2B67_18330 (pdhA)
Enzymes [BR:
scye01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
R2B67_18330 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
DUF6103
HupE_UreJ
Motif
Other DBs
NCBI-ProteinID:
WOP10375
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Position
4142182..4143342
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AA seq
386 aa
AA seq
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MTVESTAAARKPRRASKRTSAAKKPQSSEPQLVQLLTPEGERVEHPDYSIDLSADELRGL
YRDMVLTRRFDAEATALQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREHGVAW
CRGVDPTNLLGMFRGVNHGGWDPTTNNFHLYTIVIGSQTLHATGYAMGVAKDGADSAVIA
YFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTERQTRVPLYQRAQGYGFPG
VRVDGNDVLACLAVTRSALERARRGEGPTLVEAFTYRMGAHTTSDDPTKYRADDERAAWE
AKDPILRLRTYLESSGHADEAFFTELETESETLGKRVREVVRAMPDPEPLSLFEHGYADG
NSLVDEERAQFAAYQASFADSAEEGK
NT seq
1161 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgccgcgcgtaaaccgcgacgcgccagtaagcggaccagc
gccgcgaagaagccgcagagttccgagccccagctcgtgcagctgctgacgcccgagggc
gagcgggtcgagcacccggactacagcatcgacctgagcgccgacgagctgcgcggcctg
taccgggacatggttctgacccgccgcttcgacgccgaggcgaccgccctccagaggcag
ggggagctgggcctgtgggcctcgctgctgggccaggaggccgcgcagatcggcagcggc
cgggcgctgcgcgacgacgactacgtcttcccgacctaccgtgagcacggtgtggcctgg
tgtcgcggggtcgaccccaccaacctgctgggcatgttccgcggggtgaaccacggtggc
tgggacccgacgaccaacaacttccacctgtacacgatcgtcatcggctcgcagaccctg
cacgccaccggctacgccatgggcgtcgccaaggacggcgcggactcggccgtgatcgcg
tacttcggtgacggtgcctccagccagggcgatgtcgcggagtcgttcaccttctccgcg
gtctacaacgccccggtcgtgttcttctgccagaacaaccagtgggccatctccgagccc
accgagcgccagacccgcgtgccgctctaccagcgcgcgcagggttacggcttccccggc
gtccgcgtcgacggcaacgacgtcctcgcgtgcctcgccgtcacccgctccgcgctggag
cgcgcccgccgcggtgagggcccgaccctggtcgaggcgttcacgtaccgcatgggcgcc
cacaccacctccgacgacccgacgaagtaccgggccgacgacgagcgcgccgcgtgggag
gcgaaggacccgatcctgcggctgcgcacgtacctggaaagctccggccacgccgacgag
gcgttcttcaccgagctggagacggagagcgagaccctcggcaagcgcgtacgcgaggtg
gtacgggcgatgcccgacccggagccgctgtccctcttcgagcacggctacgccgacggc
aactccctcgtcgacgaggagcgtgcccagttcgccgcctaccaggcatcgttcgccgac
tctgccgaggagggcaagtag
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