Streptomyces cynarae: N8I84_11655
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Entry
N8I84_11655 CDS
T09435
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scyn
Streptomyces cynarae
Pathway
scyn00300
Lysine biosynthesis
scyn00550
Peptidoglycan biosynthesis
scyn01100
Metabolic pathways
scyn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scyn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
N8I84_11655 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
N8I84_11655 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
N8I84_11655 (murF)
Enzymes [BR:
scyn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
N8I84_11655 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DHHA1
DUF2126
Motif
Other DBs
NCBI-ProteinID:
UXY19303
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Position
unmamed1:complement(2480946..2482361)
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AA seq
471 aa
AA seq
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MIALSLAEIAEVVGGQTHDIPDPSVQVTGPVVRDSREVGPGCLFVAFVGERVDGHDFAQA
AVEAGAAAVLGSRPVGVPAIVVDDVQAALGALARHVVSRLGATLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSLNNEIGLPLTALSATEDTRFLVLEMGARGIGHIRYLTELTPPRV
GVVLNVGSAHIGEFGGREQIAQAKGELVESLPSSDADGIAVLNADDPYVRAMSSRTKAKV
ILFGESDEADVRAENVRLTDSGQPAFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSADEIAVALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMKAALRALAAMGRGRR
TWAVLGKMAELGDEALAEHDAVGRLAVRLNVGKLVAVGGREASWLQLGAYNEGSWGEESV
HVSDAQAAIDLLRSELRPGDVVLVKASRSVGLESVAQALLETGAEGEVAAR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagaagtcgtcggcgggcagacgcatgacata
ccggacccgtccgtccaggtcaccgggccggtcgtccgggactcccgcgaggtcgggccc
ggttgcctcttcgtcgccttcgtcggcgaacgcgtggacggccacgacttcgcgcaggcg
gccgtcgaggccggtgccgccgccgtgctggggtcgcgccccgtcggcgtgcccgcgatc
gtcgtggacgacgtccaggccgccctcggcgccctcgcgcgtcacgtcgtctcacggctg
ggggcgaccctcgtcgccctcaccggctccgcgggcaagaccagtaccaaggacctcatc
gcccaggtgctgcggcgcaaggcgccgaccgtgttcacacccggctcgctcaacaacgag
atcgggctgccgctgaccgctctcagcgccaccgaggacaccaggttcctcgtcctggag
atgggcgcccgcggtatcggccacatccgctacctcaccgagctgaccccgccgagggtc
ggtgtcgtgctcaacgtcggctccgcccacatcggcgagttcggcggccgcgaacagatc
gcacaggcgaagggcgaactcgtcgagagtctgccctcctcggatgccgacggcatcgcg
gtcctcaacgccgacgacccgtacgtgcgtgccatgtcctcccgtacgaaggcgaaggtg
atccttttcggagagtccgacgaagcggacgtacgcgccgagaacgtgagactcacggac
agcggacagcccgccttcaggcttcacacaccctccggtgcatccgatgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgcagacgagatcgccgtcgcgctctccgaggcgggctccctctcccgctgg
cggatggaggtcaccgagcgccctgacggcgtgaccatcgtcaacgacgcctacaacgcc
aacccggagtccatgaaggccgccctgcgcgcgctggccgccatgggccggggacggcgg
acctgggcggtgctcggcaagatggccgagctcggggacgaggcgctcgccgagcacgac
gcggtcggacggctcgccgtccggctcaatgtcggcaagctcgtcgcggtcgggggcagg
gaagcgtcctggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggcgatcgacctgttgcgcagcgagttgcgcccgggagac
gtcgtactcgtgaaggcgtcccggtcggtcgggctcgagagcgtggcgcaggcgctgctc
gagaccggtgccgagggtgaggttgccgcccgatga
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