Streptomyces cynarae: N8I84_22980
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Entry
N8I84_22980 CDS
T09435
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
scyn
Streptomyces cynarae
Pathway
scyn00860
Porphyrin metabolism
scyn01100
Metabolic pathways
scyn01110
Biosynthesis of secondary metabolites
scyn01120
Microbial metabolism in diverse environments
scyn01240
Biosynthesis of cofactors
Module
scyn_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:
scyn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
N8I84_22980
Enzymes [BR:
scyn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
N8I84_22980
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
N8I84_22980
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
RTP1_C2
Motif
Other DBs
NCBI-ProteinID:
UXY21235
LinkDB
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Position
unmamed1:5010720..5012426
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AA seq
568 aa
AA seq
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MSPTTLPAGLEHGHVTFLGAGPGDPGLLTLRAVEALANADVLVGEHEVLDVVRTHARAGV
AELNTDTDPSTGAYPGAGTPQLTVVDGESTAAGVPALRDAAHLVMEAARGGKRVVRAVSG
DPGLDAYAAGEMLACAAEGVPFEVVPGVATAVGVPAYAGVPLRDAQGADVRFVDARTASD
RCWTEVGASDGTVVVSTTLDSVAAAAGELVAAGRKPDTPMTVTVAGTTTRQRTWTATLGS
IAQTLKQAKVLPSPEGGRAVIAVVGERSAAAQRDQLSWFENKPLFGWKVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVRAVREKFE
EYGLDARAFAGIKVAAVGEQTAKALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGLKR
RAAALAAGDPVTRPSERRPGARRRRSTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacccttcccgccggccttgaacacgggcacgtcaccttcctcggtgcc
ggacccggagatccgggacttctcacactgcgcgccgtcgaggcgctggccaacgcggac
gtcctcgtcggcgagcacgaggtgctcgacgtcgtgcgcacgcatgccagagcgggcgtc
gccgaactcaacacggacacggacccctccacgggtgcgtatccgggcgcgggcacgcct
cagctgacggttgttgacggcgagtcaacagccgctggtgtccctgcgttgcgggatgcc
gcacatcttgtcatggaggctgcgcggggcggcaagcgggtcgtccgtgcggtgtccggc
gaccccggcctggacgcgtacgcggccggcgagatgctggcgtgcgccgccgagggcgtg
ccgttcgaggtcgtccccggcgtcgcgaccgcggtgggcgtgcccgcgtacgcgggtgtg
ccgctgcgggacgcgcagggcgcggacgtccggttcgtggacgcccggaccgcctccgac
cgctgctggacggaggtcggcgcgtccgacggcacggtcgtggtgtccacgacgctggac
tcggtggcggcggccgccggggagctggtggccgcgggccgcaagccggacaccccgatg
acggtgacggtcgccggtacgacgacgcggcagcgcacctggaccgccaccctcggctcc
atcgcgcagacgctgaagcaggcgaaggtcctgccgtcccccgagggcgggcgtgcggtg
atagccgtggtcggtgagcgttccgccgccgcccagcgcgaccagctgtcgtggttcgag
aacaagccgctgttcggctggaaggtcctcgtgccgcgtacgaaggagcaggcggcgtcg
ctctccgaccagctgaggtcctacggggccgtgccgcacgaggtcccgacgatcgcagtg
gagcccccgcgcaccccgcagcagatggaacgagcggtcaagggcctggtgacgggccgc
tacgagtggatcgcgttcacgtcggtcaacgcggtgcgggcggtccgggagaagttcgag
gagtacggcctggacgcgcgcgccttcgcgggcatcaaggtcgcggcggtcggcgagcag
acggcgaaggcgctggtggacttcggcgtgaagccggatctggtgccgagcggcgagcag
tcggcggccggcctgctggaggactggcccccgtacgacccggtcttcgacccgatcgac
cgcgtgttcctgccgcgcgccgacatcgcgaccgagaccctggtcgccggcctgatcgaa
ctcggctgggaggtcgacgacgtgacggcctaccggacggtccgcgcctcgcctccgccg
gccgagacacgtgaggcgatcaagggcggcggtttcgacgcggtcctgttcacgtcgtcc
tccacggtccggaacctggtcggcatcgcgggcaagccgcacaacgtgacggtgatcgcg
tgcatcggcccggcgaccgcgaagacggcggaggagcacggtctgcgtgtggacgtcatg
gctccggagccgtcggtccacaagctggcggaggcgctggcggacttcggcctcaagcgc
cgggccgccgcgctggcggccggggatccggtgacgcgtccgagcgagcggaggccgggg
gcgcggaggcgtcgctcgacgacgtag
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