Streptomyces cynarae: N8I84_29145
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Entry
N8I84_29145 CDS
T09435
Symbol
thyX
Name
(GenBank) FAD-dependent thymidylate synthase
KO
K03465
thymidylate synthase (FAD) [EC:
2.1.1.148
]
Organism
scyn
Streptomyces cynarae
Pathway
scyn00240
Pyrimidine metabolism
scyn00670
One carbon pool by folate
scyn01100
Metabolic pathways
scyn01232
Nucleotide metabolism
Module
scyn_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
scyn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
N8I84_29145 (thyX)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
N8I84_29145 (thyX)
Enzymes [BR:
scyn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.148 thymidylate synthase (FAD)
N8I84_29145 (thyX)
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Gene cluster
GFIT
Motif
Pfam:
Thy1
Intein_splicing
HNH
HNH_5
zf-Tbcl_FmdE
Motif
Other DBs
NCBI-ProteinID:
UXY24692
LinkDB
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Position
unmamed1:6394658..6395857
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AA seq
399 aa
AA seq
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MAQVRRGETNHYLGLYDNREAADCAVAEFREKHPSTRLRKLESVRRNHVRCYDEETLTAR
RAPILDVIQSGIKPLIKLTTAGGKVLRCTVDHAVLTPEGWRKAGELAVGDAVMTAGTAPR
PSERLVPPSLRRGVGVWTSMQRDRLIGETDTCHLCGEPFPRDQLALDHVVPVAEDLTRAL
DERNLAPACEPCHAAKSAEEQKLARRGGKIAVAVPDPIVSIVDDGEEMTYDLTVEGPWHN
FLANGVVVHNSYNEESGRYRELQPVFYVPGEDRKLVQQGRPGKYEFVPGTDTQHAIMERA
MQDSYIHAYERYREMLASGVAREVARAVLPVGLFSSMYATCNARSLMHFLGLRTQHELAK
VPSFPQREIEMVGERMEAEWARLMPLTYAAFNANGRVAP
NT seq
1200 nt
NT seq
+upstream
nt +downstream
nt
atggcgcaggtccgccgcggagagaccaaccactacctggggctctatgacaatcgggag
gccgccgactgcgccgttgcggaattccgcgagaagcacccctccacccgtctccgcaag
ctcgaatcggtcaggcgcaatcacgttcgctgctacgacgaggagacgctgacagcgcgg
agggcgcctatcctcgatgtcattcagtcgggcatcaagcctttgatcaagctcaccact
gccggtggcaaggtccttcgctgcaccgtcgaccatgcggtgctcaccccggaaggctgg
cggaaggccggagagctggccgtgggcgatgcggtgatgaccgccgggacggcgccacgg
ccttcggaaaggctcgttccgcccagcctccgtcgtggcgtgggcgtctggacctcgatg
cagcgtgaccgcctgatcggcgagaccgatacatgtcacctgtgtggagagcccttccca
cgtgaccagctcgcgctcgatcacgtcgtacccgtggccgaggatctgacgcgcgcactc
gacgagcgcaatctggcccccgcctgtgagccgtgccacgcagccaagagtgccgaggag
cagaagctggcacgtcgcggcggaaagatcgccgtagctgttccggatccgatcgtgtcc
atcgtggacgacggcgaggagatgacgtacgacctcacggtggagggtccctggcacaac
ttcctggccaatggcgttgttgtccacaactcctacaacgaggagtccggccggtaccga
gaactccagcccgtcttctacgtccccggcgaggaccgcaaactcgtccagcagggacgt
ccgggcaagtacgagttcgtaccgggcaccgacacgcagcacgcgatcatggagcgcgcg
atgcaggattcgtacatccatgcgtatgagcgttacagggagatgctcgcctccggcgtc
gcccgtgaggtcgcccgcgcggtcctcccggtcggtctgttctcctcgatgtacgccacg
tgcaacgcgcgctcgctgatgcacttcctcggcctgcgcacccagcacgaactggcgaag
gtgccctccttcccgcagcgggagatcgagatggtcggcgagaggatggaggccgagtgg
gccaggctcatgccgctcacgtacgccgcgttcaacgcgaacggccgcgtcgcgccgtaa
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