Streptomyces dangxiongensis: D9753_04225
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Entry
D9753_04225 CDS
T08044
Name
(GenBank) SDR family NAD(P)-dependent oxidoreductase
KO
K15671
rifamycin polyketide synthase modules 4, 5 and 6
Organism
sdd
Streptomyces dangxiongensis
Pathway
sdd01051
Biosynthesis of ansamycins
sdd01052
Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:
sdd00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
D9753_04225
01051 Biosynthesis of ansamycins
D9753_04225
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
sdd01008
]
D9753_04225
Polyketide biosynthesis proteins [BR:
sdd01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Rifamycin PKS
D9753_04225
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
SpnB_Rossmann
PKS_DH_N
PS-DH
KAsynt_C_assoc
PP-binding
adh_short
RhiE-like_linker
CurL-like_PKS_C
Thiolase_N
GDP_Man_Dehyd
Polysacc_synt_2
Epimerase
NmrA
Docking
ACP_syn_III
SDR
Motif
Other DBs
NCBI-ProteinID:
AYN38261
UniProt:
A0A3G2J9A1
LinkDB
All DBs
Position
complement(911696..927805)
Genome browser
AA seq
5369 aa
AA seq
DB search
MSGPDDQIVNALRASLKENARLQQENSKLAAVAAEPIAIVSMACRYAGGIRTPEDLWRVV
TDGTDVYTTFPEDRGWDLEGLYHPDPDNPGTTYVREGAFLHEAAEFDAAFFGISPREALA
MDPQQRQLLEVTWETLERAGIDPHSVRGSDIGVFAGIVHQDYAPDLSGHEGYLSLERALG
TAGGVASGRVAYTLGLEGPAVTVDTMCSSSLVAIHLASQALRRGECSMALAGGSTVMATP
GGFVGFARQRGLAFDGRCKSYAAAADGSGWAEGVGVVLLETLSHARERGHRVLAVVRGSA
VNQDGASNGLTAPNGPSQQRVIRKALSSAGLSTSDIDMVDGHGTGTVLGDPIEAQAILAT
YGQDRPAGQPLRLGSVKSVIGHTQAASGVAGVINMVQAMRHGLMPASRHIDAPTPQVDWS
SGAVELLTEAREWPETDRPRRVGVSAFGASGTNAHLILEQAPEEDAPAAAVTPGGAVPLV
VSAASAASLTGQAGRLAAFLDGTDTPLAAVAGTLATRRAVLGERAVVVAETRDEALAALT
ALARDEQAPGTVRGTAGAAGAGKTVLVFPGQGTQWIGMGRELLGTSPVFAERIEECARAL
ERWVDWDLKAVLRGDADTGLLTRVDVVQPASFAVMVGLAAVWASVGVVPDAVVGHSQGEI
AAACVAGALTLDDAARIVAVRSQVIRGRLAGLGGMASVALTEDDVTARLERWAGRVEVAA
VNGPASVVIAGDAEALDEVLDTLEDQGVRVRRIAVDYASHSRHVQAVQEALTEAFADIRG
RAPAIPFLSTVTGEWVRDAGVLDGGYWYRNLRRQVRFGPAVATLLAEGHTVFVESSAHPV
LVQPVTEIADAADAVVTGSLRRDDGGLRRLLTSMAEVFAGGVAVDWKGILPEAARTAHVD
LPTYAFDRRRYWIQLTPNGGDAASLGVTGTDHPLLGAVVPLPQTDGLVLTSRLSLRTHPW
LADHAMQGVVIVPGTVYVDLAVRAGDEFGCGTLEELVIEAPLVLPAQGGVRVQVAVGGAT
GNGSRAVDVYSLREDAGEDGHGEWTRHATGLLSSAPARSTAPAADFTAWPPPGAEPVAID
DFYGALVARGYSYGPAFQGLRGVWRRGEELFAEAALPQDHREDADKFAIHPALLDAALHT
NAFANPDDDRNVLPFAWNGLVLHAEGASALRVRVAPAGPDALSFQAADETGDLVLTMDSL
VSLPVSAEQLGAAAGGNQDALFAVDWVPLPAAEGVSTAPAWVPVADADAVRALTARESVP
AAAILDAYSDGADAQTLTCRVLDVLQAWLTTPGLEAARLVVATRGAVPAGGDATLTDPAG
AAVWGLVRAAQAENPDRVVLADLDPATATGAGPVLGQLLATGEPQLAVRGTALSAPRLVR
AEQTATAGSTGSADTATAGSTGTADPATAAQAPAVGPVPAFDPDGTVLITGGTGSLGALV
ARHLVQRHGVRHLVLAGRRGPDATGAAALTADLTGLGADVSVVACDVSDRDAVAALLRDL
PAAHPLTGLVHLAGILDDGVISALTEERIAGVFAPKATAVRHLDELTRQLAPALRSFVVF
SSAAALLGSAGQGNYAAANAFLDALMAHRRAAGLPGVSLAWGLWEQSAGLTAHLSETDQA
RMSRGGVLALTADEGLALLDTGLHADRALLVPIKLDLRALRSDAASGGTVPHLLRGLVRA
GRRSARAAAGDGSALLRRLAGLAEAEQEAVLLGVIQAEATAVLGFSGPELAQGTRGFGDI
GFDSLTAIELRNRLSAATGVTLPATLIFDYPTPVALARHLREELGESAAGAAAPTVVATD
PDEPIAIVGMACRLPGGVTDPAGLWRLVLDRREGMTGFPDDRGWNLDELFDADPDKAGTS
YVHKSGFLQGAAEFDADFFGISPREALAMDPQQRLLLEATWEALENAGIDPGSTRGADIG
VFSGVSIHDYLESLSNMPPELEGYVTTATAGSVASGRVSYVFGFEGPAVTVDTACSSSLV
AMHLAAQALRQGECSLALAGGVAVMGSPIGVLGMSRQRGLAADGRVKAFSAGADGTVLSE
GVGIVVLERLSEARRKGHQVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRRALAAAGLA
ASDVDAVEAHGTGTALGDPIEAQALLATYGRDREQPLWLGSLKSNIGHTQAAAGVAGVIK
MVQALRHGVLPPTLNVTEPTPQVDWSAGAVELVTEARQWPESGRPRRAGVSSFGISGTNA
HLILEQAPEEPVTRPADRADGPVPLVVSAASEGSLTGQAERLAARTADTDASLADIAAAL
VTRRATLSERAVVLAGSRAEAVAGLAALARGESAAGLVTGGAGAAGRTVLVFPGQGSQWT
GMGRELLETSPVFAERVEECARALEPWTDWDLKAVLRGEADAALVARVDVVQPASFAVMI
GLAAVWASVGVVPDAVVGHSQGEIAAACVAGALSLDDAARIVAVRSRVIAGELAGRGGMA
SVALPEADAAARIAAWDGRVEVAAVNSPSSVVIAGDAEALDEALAALEAEGVRVRRVAVD
YASHTRHVEAIENTLAEALAEVRGQAPLVPFFSTVTGEWVREAGVLDGGYWYRNLRQQVR
FGPAIAALLTEGHTVFVESSAHPVLVQPVNEITDDTRADAVATGSLRREEGGLRRLLTSM
AEVFVKGVPVDWTGVLPEGAGEAHVDLPTYAFDHRPYWLRTAPATGAASLGQASADHPLL
GAVVPLPQSDGLVLTSRLSLRTHPWLADHVVGGAVVVPATALVELALRAGDEAGTATLEE
LTVETPLLLPEDGGIRVQVAVGGPDETGARTVDVYAAGEDPEAAAWTRHATGRLAHAPLT
TPGTSADLTLWPPTGARPADIDEFYDDLLRLGHPFGPAFRGVRTLWRRGDEVFTEVALPE
EQRAGAERFGIHPALLDASVQSGLRHAATADPDGGDQRLWQPAAWQGLTLHATGATTLRV
RLAPSGDGRLSLEATDGTGGLVVTLDALGFLPVAADQLTPAPADGGHSLYRVDWTDLPAP
DSDGQQVPPWVPLFHADEVGILAGAATGPMVAVVEAVTPDGTAEGTADGALSLANRMLAM
LQAWFAAPGLDESRLVVLTRGAVPAGGDTAVTDPAGAAVWGLVRAAQAENPGRVVLIDTD
TDPDIAYGTTVEPLLATVLASGEPQVAVREAALSVPRLVRAEPSEGERSEGESSVSFRPG
GTVLVTGGTGSLGALVARHLVVRHGVRHLVLAGRRGTEAEGATELVAELSGLGAESVSLV
AADVSDRTQVAQLLESIPAEHPLTGVVHTAGVLDDGVIGALTPQRMAGVFAPKADAAAHL
DELTRTLDLTAFAVYSSGAGLFGSAGQGNYAAANAYLDGLMARRRAAGLPAVSLAWGLWE
QDTGLTAHLSETDQARMSRGGVRALPPEEGLALFDAALGAGQALLVPIKLDLRAARADAA
SGGTVQPLMRGLIRVTRQAARTATADRTGGGLADRLAGLGPDEQEALLLDIVRGQVAAVL
GHAGADQVRAEKAFKDAGFDSLTSVELRNRVREATGLTLPTTVVFDYPTPLALARHLHSH
FGHVTAAPAAPAPAVAAADPGEPIAIVGMACRLPGGVTSPEGLWQLVAEGRDAMSGFPSD
RGWDLDGLFDSDPGRVGTSYVDQGGFLHDAGLFDAGFFGISPREALAMDPQQRLLLETSW
EALERAGIDPTSLKGTDVGVFSGVMTQGYGFGGELPPELAGFTATGSAGSVASGRVSYVL
GLEGPAVTVDTACSSSLVALHLAAQALRNGECSMALAGGATILANPYTFVEFSRQQALSP
DGRCKAFADAADGTGWAEGAGVVVLERLSEARRKGHRVLAVVRGSAVNQDGASNGLTAPN
GPSQQRVIRKALANAGLSVAEVDAVEAHGTGTVLGDPIEAQALLATYGQDREEPLWIGSV
KSNLGHAQAAAGVAGVIKTVEALRHAVLPPTLHVDRPSTEVDWSAGAVEVLTEARAWPET
GRPRRAGVSAFGVSGTNAHVILEQAPEEEPAAKPVAPADGVLPLVISARGADALAGQAGR
LAEFAAATDAPTAAVAGALVSRRAVLSERAVVVAGSREEAVAGLAALAAGESSPAVVTGT
ESSGATVIVFPGQGSQRLGMGRELYDRHPVFARAFDEACAALDAQLAGWADHPVKDVVFG
EVGNAGGGLLDQTIFTQAGLFAVESALFRLVESWGVRPDVVAGHSIGEVVAAHVAGVLSL
TDAAALVAARGRLMQALAPVGAMVAVAASEAEIAGHLGAGVDLAAVNAPGSVVLSGDEEA
VVAVAEKLREQGRRVKRLTVSHAFHSALMEPMLADFTAALSGLTWHEPTLPVVSNVTGRL
AEPGRLTDPAYWVDHVRRPVRFADGIAASGGSVFLELGPGGALTGAIAQSAGDDAVSVPA
LRDDRGEAQTLLLSVAELFVRGTNVNWAAVLPEGATDAHVDLPTYAFDHRHYWLRMAPAT
DAVALGQGTADHPLLGAVVEVPETGGVLFTSRLSLRTHPWLADHAVGGVVLVPGTGLVEL
AVRAGDEVGSGVLDELVIEAPLVVPEHGGVRVQVAVGGPDDSGLRTVSVYSARENTTGEI
DTDAWTRHATGTVTASAADTPAFDTTVWPPAGAEPVDLDITAFYTDLLSHGYAYGPAFQG
LRAVWRRGEEIFAEVALPDEQRDEAARFGLHPALLDAALHTDAFAQPDDGHNVLPFSWNG
LELHAAGAASLRVRITPRGTDALSLVAADENGGLVLTVDSVTFRPVDVGQLDAAATAGED
RDALFTVAWTDLPAPASTPDTAPAWARVATAAEVTALRGEVSEAAVLDLRGTGDGDEETL
TRTAAALEVVQAWLADEDAEDARLLVVTRGAVPAGGAATVTDAAGAAVWGLVRAAQAENP
DRIVLLDLDPATDPATDEPSDGLLATVLASGEPQVAVREAALSVPRLVRAEPSEGERSEG
ESSVSFRPGGTVLVTGGTGSLGALVARHLVVRHGVRHLVLAGRRGTEAEGATELVAELSG
LGAESVSLVAADVSDRTQVAQLLESIPAEHPLTGVVHTAGVLDDGVIGALTPERLARVFA
PKVSAVQHLDELTRTLDLTAFAVFSSASGLFGSAGQGNYAAANAYLDAVAHQRRADGLPA
TSLAWGLWEQTSGMTAHLGAADQARMSRGGVLPIAPAEGMRLLDAALATAEALLVPIKLD
LRALRADAAAGRTVQPLLRGLVRTGRQPVRTTAGDSGGGLTRRLAGLAQAEQEALLLDLV
RGQVATVLGHAGAENVGPETAFKDAGFDSLTSVELRNRLRETTGLKLAATVVFDYPNPLA
LARHLHTELGTTNDALSLVHEKIEDIDSLIAGLLSDESKKADIVLRLQGLVAKCNGVVEE
TEGSAVAEQLESASADEVLDFINDELGIS
NT seq
16110 nt
NT seq
+upstream
nt +downstream
nt
atgtcgggcccggacgaccagatcgtcaacgcgctgcgcgcctccctcaaggagaacgcg
cggctgcagcaggagaacagcaaactcgcggcggtcgctgccgagcccatcgccatcgtc
tccatggcctgccggtacgcgggaggcatccgcacccccgaggacctgtggcgcgtggtg
accgacggcacagacgtctacaccacgttccccgaggaccgcggctgggacctggagggc
ctctaccaccccgacccggacaaccccggcacgacgtacgtccgcgagggcgccttcctc
cacgaggccgccgagttcgacgccgccttcttcggcatctcgccgcgtgaggccctcgcc
atggacccgcagcagcgccaactgctcgaggtgacctgggagaccctggaacgggccggc
atcgacccgcactccgtgcgcggcagcgacatcggcgtcttcgccggcatcgtccaccag
gactacgcccctgacctcagcggccacgagggctacctcagcctggaacgggccctgggg
accgcgggcggtgtcgcctccggccgcgtcgcctacaccctcggcctggaggggcccgcg
gtcaccgtcgacaccatgtgctcgtcctccctcgtcgccatccacctcgccagccaggcg
ctgcgccgcggcgagtgctccatggcgctcgccggcggctccaccgtgatggccaccccc
ggcggcttcgtcggcttcgcccgccagcgcggcctcgccttcgacggccgctgcaagtcc
tacgccgccgccgccgacggctccggctgggccgagggcgtcggcgtcgtcctcctggag
acgctgtcgcatgcccgggagcgcggccaccgcgtcctcgccgtcgtccgcggctcggcc
gtcaaccaggacggcgcgtccaacggcctgaccgcccccaacggcccctcccagcagcgc
gtcatccgcaaggcgctgagcagcgccgggctgagcacctccgacatcgacatggtggac
ggccacggcaccggcaccgtcctcggcgaccccatcgaggcccaggcgatcctcgccacc
tacggccaggaccgtcccgccggacagccgctgcggctgggctccgtgaagtcggtcatc
ggccacacccaggccgcctccggcgtcgccggcgtcatcaacatggtgcaggccatgcgc
cacggcctgatgccggccagccggcacatcgacgcccccaccccgcaggtcgactggtcg
tccggtgccgtggagctgctcaccgaggcccgggagtggcccgagaccgaccggccgcgc
cgcgtcggcgtctccgccttcggcgccagcggcaccaacgcccacctgatcctggaacag
gcccccgaggaggacgcgccggccgccgccgtcaccccgggcggcgccgtgccgctggtg
gtgtcggcggcctccgccgcctcgctcaccggccaggccggccgactcgccgccttcctg
gacggcacggacacccccctcgcggccgtcgcgggcaccctcgccacccggcgagcggtg
ctcggcgaacgtgccgtcgtggtcgcggagacccgcgacgaggcactggccgcgctgacc
gccctcgcccgcgacgagcaggcccccggaaccgtccggggcaccgccggcgccgccggg
gccggcaagaccgtcctggtcttccccggccagggcacccagtggatcggcatgggccgc
gaactcctcggcacctccccggtgttcgccgagcggatcgaggagtgcgcccgggccctg
gaacgctgggtggactgggacctcaaggccgtgctgcgcggcgacgccgacaccggcctg
ctgacccgcgtggacgtggtgcagcccgcgagcttcgccgtcatggtcggcctggccgcc
gtctgggcgtccgtgggtgtcgtaccggacgcggtggtcggtcactcgcagggcgagatc
gccgccgcctgcgtcgccggcgccctcaccctggacgacgccgcccgcatcgtcgccgtc
cgcagccaggtcatccgcggccggctcgccggactgggcggcatggcctcggtcgcgctc
accgaggacgacgtcaccgcccggctggagcgctgggccggccgggtcgaggtggccgcc
gtcaacggcccggcctccgtcgtgatcgccggtgacgccgaggccctcgacgaggtcctg
gacaccctggaggaccaaggcgtgcgcgtacggcgcatcgccgtggactacgcctcccac
agccggcacgtgcaggccgtgcaggaggccctcaccgaggccttcgcggacatccggggc
cgggcccccgccatcccgttcctgtccaccgtcaccggcgagtgggtccgtgacgcgggc
gtcctggacggcggctactggtaccgcaacctgcgccggcaggtccgtttcggccccgcc
gtcgccaccctcctcgccgagggccacacggtgttcgtcgagtccagcgcccaccccgtc
ctcgtccagccggtcaccgagatcgccgacgcggccgacgccgtggtcaccggctccctg
cgccgtgacgacgggggcctgcgccgcctgctcacctccatggccgaggtcttcgccggc
ggcgtggccgtcgactggaagggcatcctgcccgaggcggcccgcaccgcccacgtcgac
ctgccgacgtacgccttcgaccgccgccgctactggatccagctcacccccaacggcggt
gacgccgcctccctcggcgtgaccggcaccgaccatccgctgctcggcgcggtggtaccg
ctgccgcagaccgacggactggtcctcacctcccggctctccctgcgcacccacccctgg
ctggccgaccacgccatgcagggcgtcgtcatcgtcccgggcaccgtctacgtcgacctc
gcggtgcgcgccggcgacgagttcggctgcggcaccctggaggaactcgtcatcgaggcg
ccgctggtgctgcccgcgcagggcggcgtccgcgtccaggtcgccgtcggcggcgccacc
gggaacggttcgcgcgccgtcgacgtgtactcgctgcgggaggacgccggcgaggacggg
cacggcgagtggaccaggcacgccaccggcctgctgtccagcgcacccgcccgatccacg
gcgcccgccgccgacttcaccgcctggccgccgcccggcgccgaacccgtcgccatcgac
gacttctacggcgccctggtcgcccgcggctactcctacggccccgccttccagggcctg
cgcggtgtgtggcggcgcggcgaggaactcttcgccgaggcggccctgccgcaggaccac
cgggaggacgccgacaagttcgccattcacccggcgctcctcgacgcggccctgcacacc
aacgccttcgccaacccggacgacgaccgcaacgtcctgccgttcgcctggaacggcctc
gtcctgcacgccgagggcgcctccgccctgcgggtacgggtcgcgcccgccggccccgac
gccctgtcgttccaagccgccgacgagaccggcgacctggtgctgaccatggactccctg
gtgtccctgccggtctccgccgaacagctcggcgccgcggccggcgggaaccaggacgcc
ctgttcgccgtcgactgggtgccgctgcccgccgccgagggcgtctccaccgcacccgcc
tgggtgccggtcgccgacgccgacgccgtgcgcgcgctcaccgcccgcgagagcgtgccc
gccgcggcgatcctggacgcctacagcgacggcgccgacgcccagaccctgacctgccgc
gtcctggacgtcctccaggcctggctgaccacacccggtctcgaagcggcccgtctggtg
gtcgccacccggggagcggtgcccgccggcggcgacgccactctcaccgacccggccggc
gcggccgtgtggggcctcgtccgcgccgcgcaggccgagaaccccgaccgggtcgtcctg
gccgacctcgacccggccaccgccaccggggccggccccgtcctcgggcagctcctcgcc
accggcgaaccacagctcgccgtgcgcggcaccgccctgtcggcaccccgcctggtccgc
gcggagcagacggccacggccggttccaccggttcggcggacacggccacggccggttcc
accggcacggcggaccccgccaccgccgcccaggcccccgcggtcgggcccgtgcccgcg
ttcgaccccgacggcaccgtcctgatcaccggtggtaccggttcgctcggcgcgctcgtc
gcccggcacctggtccagcggcacggcgtacgccacctggtgctggccggccggcgcggt
cccgacgccaccggtgccgccgctctcacggccgacctgaccggcctcggcgcggacgtc
tccgtcgtcgcctgcgacgtctccgaccgggacgcggtcgccgcgctgctgcgcgacctg
ccggccgcgcacccgctgaccggtctggtgcatctcgccggcatcctcgacgacggtgtg
atcagcgcgctcaccgaggaacggatcgccggggtcttcgcccccaaggccaccgccgta
cggcatctggacgagctgacccgacaactcgcgcccgccctgcgctcgttcgtggtgttc
tcctccgccgccgccctcctcggctccgccggccagggcaactacgcggctgccaacgcc
ttcctggacgccctcatggcccaccgccgcgcggccgggctgcccggcgtctccctggcc
tggggcctgtgggagcagagcgccggtctgaccgcgcacctcagcgagaccgaccaggcc
cgcatgagccgcggtggcgtcctcgcgctcaccgcggacgagggtctcgccctcctcgac
accggtctgcacgccgaccgggccctgctggtcccgatcaagctggacctgcgcgcgctg
cgctccgacgcggcctccggcggcaccgtgccgcacctgctgcgcggcctggtccgggcc
ggccggcgctccgcgcgggccgccgccggtgacggcagcgctctcctgcgccgcctcgcc
ggcctcgccgaggccgagcaggaagccgtcctgctgggcgtgatccaggccgaggccacc
gccgtcctgggcttcagcggtcccgaactcgcccagggcacccgcgggttcggcgacatc
ggcttcgactcgctcaccgcgatcgagctgcgcaaccggctgtccgccgccaccggcgtc
acgctgcccgccacgctcatcttcgactaccccacgccggtggcactcgcccgccatctg
cgcgaggaactcggcgagagcgcggccggcgccgccgcccccacggtcgtcgccaccgac
ccggacgagcccatcgccatcgtcggcatggcctgccggctgccgggcggcgtcaccgac
ccggccggcctgtggcggctggtcctcgaccgccgcgagggcatgacgggcttccccgac
gaccgcggctggaacctggacgagctgttcgacgccgatcccgacaaggccggcacctcc
tacgtccacaagagcggattcctccagggcgccgccgagttcgacgccgacttcttcggc
atctccccccgcgaggcgctggccatggacccccagcagcggctgctgctggaagcgacc
tgggaggccctggagaacgccggcatcgaccccggctccacccgcggcgccgacatcggc
gtcttctccggcgtctccatccacgactacctggagtccctcagcaacatgccccccgag
ctggagggctacgtcaccaccgccaccgcgggcagcgtcgcctcgggccgggtgtcgtac
gtgttcggcttcgagggtcccgcggtcaccgtcgacaccgcctgttcctcgtcgctcgtc
gctatgcacctggcggcccaggcactgcggcagggcgagtgctcgctggcgctggccggc
ggcgtcgccgtgatgggctcgccgatcggcgtgctaggcatgtcccgccagcgcggcctc
gccgcggacggccgggtcaaggcgttctccgcgggcgccgacggcaccgtcctgtccgag
ggcgtgggcatcgtcgtcctggaacgcctgtcggaggcccgccgcaaggggcaccaggtg
ctcgcggtgctgcgcggcagcgcggtcaaccaggacggcgcgtccaacggcctcaccgcc
ccgaacggcccctcgcagcagcgggtcatccgccgggcactggcggctgccggtctggcc
gcctccgacgtggacgccgtggaggcgcatggcacgggcacggcgctcggtgacccgatc
gaggcgcaggccctgctcgccacctacggccgggaccgcgaacagccgctgtggctgggc
tcgttgaagtccaacatcgggcacacgcaggccgccgccggtgtcgccggcgtcatcaag
atggtccaggcgctgcgccacggcgtcctgccgcccaccctcaacgtcaccgagccgacc
ccgcaggtcgactggtcggccggggccgtcgagctggtgaccgaggcccggcagtggccc
gagtccggccgtccgcgccgggccggtgtctcctccttcggcatcagcggtaccaacgcg
cacctcatcctggagcaggcacccgaggagccggtcacacgaccggcggaccgggccgac
ggcccggtgccgctggtggtgtcggcggcctccgagggctcactgaccggacaggcggaa
cggctcgccgcccgcaccgcggacaccgacgcgtcgctcgcggacatcgcggccgccctc
gtcacgcgccgggccacgctgtccgagcgggccgtggtgctcgccgggtcccgcgcggag
gcggtggccgggctggccgcgctggcgcggggcgagtcggccgccgggctggtgaccggc
ggtgcgggcgccgcgggacggacggtactggtcttccccggccagggctcgcagtggacc
ggcatgggccgggaactgctggagacctcaccggtgttcgccgaacgggtcgaggagtgc
gcccgagccctggaaccctggaccgactgggacctgaaggcggtgctgcgcggcgaggcc
gacgccgctctcgtcgcccgcgtcgacgtcgtccagccggccagcttcgcggtgatgatc
ggcctggcggccgtgtgggcgtccgtgggtgtcgtaccggacgcggtggtcgggcattcg
cagggcgagatcgccgccgcgtgcgtggccggagcgctgtcactggacgacgcggcccgg
atcgtcgccgtacgcagccgggtgatcgccggtgaactcgcgggccggggcggcatggcc
tccgtggccctgccggaggccgacgccgccgcccggatcgccgcgtgggacggccgggtc
gaggtcgccgccgtcaacagcccctcgtcggtggtcatcgccggcgacgccgaggccctg
gacgaggcgctggccgcgctggaggccgagggcgtgcgcgtccggcgtgtcgccgtggac
tacgcctcccacacccggcacgtcgaggccatcgagaacacgctcgccgaggcgctcgcc
gaggtacgcgggcaggccccgttggtgcccttcttctccacggtgaccggcgagtgggtg
cgcgaggcgggcgtcctggacggcggctactggtaccgcaacctgcggcagcaggtccgc
ttcggaccggcgatcgccgccctcctcaccgagggccacaccgtgttcgtcgagtccagc
gcccaccccgtcctcgtccagccggtcaacgagatcaccgacgacacccgcgccgacgcg
gtcgccaccggctccctgcgccgcgaggaaggcggcctgcgccggctgctcacctcgatg
gccgaggtcttcgtcaagggcgtccccgtcgactggaccggtgtgctgcccgagggcgcc
ggtgaggcacacgtcgacctgccgacgtacgccttcgaccaccgcccctactggctcagg
accgctccggccacgggcgccgcctcactcggccaggcctccgccgaccaccccctgctg
ggcgcggtcgtcccgctgccccagtcggacgggctggtcctcacctcccggctctccctg
cgcacccacccctggctggccgaccacgtcgtcggcggggcggtcgtcgtcccggccacg
gccctggtggaactggccctgcgcgccggcgacgaggccggcaccgccaccctggaggag
ctgacggtcgagacaccgctgctgctgcccgaggacggcggcatacgcgtccaggtcgcc
gtcggcggccccgacgagaccggcgcgcggaccgtcgacgtctacgcggccggcgaggac
cccgaggccgccgcctggacccggcacgccaccggacggcttgcgcacgccccactcacc
acgcccggcacgagcgccgacctgacactgtggccgccgaccggcgcccgccccgccgac
atcgacgagttctacgacgacctgctccgcctcggccacccgttcggccccgccttccgc
ggcgtacggacgctgtggcggcgcggcgacgaggtcttcaccgaagtcgccctgcccgag
gaacagcgcgcgggcgccgagcggttcggcatccaccccgcgctcctcgacgcctccgtg
cagtccgggctgcggcacgcggccacggccgacccggacggcggcgaccagcggctgtgg
cagcccgccgcctggcaggggctgaccctgcacgccaccggcgccaccacgctccgcgtg
cggctcgccccctccggggacgggcgcctgtcgctggaggccacggacggcacgggcggc
ctcgtcgtcaccctggacgccctgggcttcctgccggtggccgccgaccagttgacgccg
gcccccgccgacggcggtcactccctctaccgcgtcgactggaccgaccttcccgcgccc
gactccgacgggcagcaggtgccgccgtgggtgccgctgttccacgcggacgaggtcggc
atcctcgccggcgcggcgaccggcccgatggtcgccgtcgtcgaggccgtcacccccgac
ggcaccgccgagggcaccgcggacggcgcgctgtctctggccaaccggatgctggccatg
ctccaggcgtggttcgccgcacccggcctggacgagtcccgcctggtggtcctgacccgg
ggcgccgttcccgccggcggcgacaccgcggtgacggacccggccggcgcggcggtctgg
gggctggtccgcgcggcccaggccgagaacccgggccgcgtcgtcctgatcgacacggac
accgaccccgacatcgcctacggcaccaccgtcgaaccgctcctcgccaccgtcctcgcc
tccggggaaccgcaggtggcggtgcgggaggcggcgctgtcggtgccgcgcctggtgcgg
gcggagccttccgagggcgaacggtccgagggtgagtcgagtgtgtcgttccgtccgggg
ggtacggtcctggtgacgggcggtacgggttcgctcggtgcgctggtcgcccgtcatctg
gtcgtacggcacggggtacggcacctggtgctggccggccggcgcggcacggaggccgag
ggcgcgacggagctggtggccgaactgtccggcctgggcgccgagtcggtgtccctggtg
gccgccgacgtgtccgaccgtacccaggtggcacaactgctggagtccatcccggccgag
cacccgctgacgggtgtggtccacacggcaggcgtcctggacgacggcgtcatcggcgcc
ctcactccgcaacggatggcgggcgtcttcgcccccaaggccgacgccgccgcccacctg
gacgagctgacccgcaccctggacctgacggcgttcgccgtctactcctccggcgccggc
ctgttcggctcggcgggccagggcaactacgccgccgccaacgcctacctcgacggcctg
atggcccgccgccgcgccgccggcctgcccgcggtgtccctggcctggggcctgtgggag
caggacaccggcctgaccgcccacctcagcgagaccgaccaggcccgcatgagccggggc
ggcgtccgcgccctgccccccgaggagggcctcgccctcttcgacgcggccctcggcgcc
ggacaggccctcctcgtcccgatcaagctggacctgcgggccgcccgcgccgacgccgcc
tccggcggcaccgtgcagcccctgatgcgcggcctgatccgcgtcacccggcaggccgcc
cggacggccaccgcggaccgaaccggcggcggcctggccgaccggctcgccggactcggc
ccggacgagcaggaagcgctgctcctcgacatcgtccgcggccaggtcgcggccgtcctc
ggccacgcgggtgccgaccaggtcagggcggagaaggcgttcaaggacgccggcttcgac
tccctcacctccgtcgaactgcgcaaccgcgtccgcgaggccaccggcctgaccctgccg
accaccgtcgtcttcgactacccgacccccctcgccctcgcccgccatctgcacagccac
ttcggacacgtcaccgcggcacccgccgccccggccccggccgtcgccgcggccgacccc
ggcgagccgatcgcgatcgtcggcatggcctgccggctgcccggcggcgtcaccagtccc
gagggcctctggcagcttgtggcggagggccgggacgcgatgtccggcttcccgtccgac
cgcggctgggacctggacggcctgttcgactccgacccgggacgggtcgggacctcgtac
gtcgaccagggcggcttcctccacgacgccggcctgttcgacgccggcttcttcggcatc
tcgccgcgtgaggcgctggcgatggacccgcagcagcggctgctcctggagacctcgtgg
gaggcgctggagcgggcgggcatcgacccgacctccctcaagggcaccgacgtcggcgtg
ttctccggcgtgatgacccagggctacggcttcggcggcgaactcccgccggagctggcc
gggttcaccgcgaccgggtccgcgggcagcgtggcctccggccgggtgtcgtacgtcctc
gggctcgaaggccccgccgtgaccgtggacaccgcgtgctcctcgtccctggtcgccctc
cacctcgcggcgcaggccctgcgcaacggcgagtgctccatggccctcgccggcggcgcg
accatcctcgccaacccctacaccttcgtggagttctcccgtcagcaggccctctcaccc
gacgggcgctgcaaggccttcgcggacgccgccgacggcaccggctgggccgagggcgcg
ggcgtggtcgtactggaacggctgtcggaggcacggcgcaaggggcaccgggtgctggcg
gtcgtccgcggcagcgcggtcaaccaggacggcgcctcgaacggcctgaccgcacccaac
ggcccctcccagcagcgggtcatccgcaaggcgctggcgaacgccggtctctcggtggcc
gaggtggacgccgtcgaggcgcacggcacgggcacggtcctcggtgacccgatcgaggcg
caggccctgctcgcgacctacggccaggaccgcgaggagccgctgtggatcggctcggtg
aagtccaacctcggccacgcgcaggccgcggcgggcgtcgccggcgtcatcaagaccgtc
gaggcactgcggcacgcggtgctgccccccacgctccacgtcgaccggccctcgaccgag
gtcgactggtcggcgggcgcggtggaggtcctcaccgaggcccgggcctggccggagacc
ggccgcccccgccgtgccggcgtctccgccttcggcgtgagcggcaccaacgcccacgtc
atcctggaacaggcacccgaggaggagccggccgcgaagccggtggcccccgccgacggt
gtgctgccgctggtgatctcggcccgcggcgccgacgcgctggccgggcaggccggccgg
ctcgccgagttcgccgccgccaccgacgccccgacggcggccgtcgccggagcgctcgtc
tcccggcgggccgtgctctccgaacgggccgtggtcgtcgccggctcgcgcgaggaggcg
gtggccggcctcgcggcactggcggccggcgagtcgtcgccggccgtggtcacgggcacg
gagagcagcggtgccacggtcatcgtgttccccggccagggctcgcaacgcctcggcatg
ggacgcgagttgtacgaccgtcacccggtgttcgcccgtgccttcgacgaggcctgcgcc
gcactcgacgcacagctcgccggctgggcggaccaccccgtcaaggacgtggtcttcggc
gaggtcggcaacgccggcggcggcctgctggaccagaccatcttcacccaggccgggctg
ttcgccgtcgagtcggccctgttccggctcgtggagtcctggggcgtacggccggacgtg
gtggccggacactcgatcggcgaggtcgtcgccgcgcacgtcgccggggtgctgtcgttg
acggacgcggcggcgctggtcgccgcccgaggccggctgatgcaggccctggcaccggtc
ggcgcgatggtcgccgtggccgcgagcgaggcggagatcgccggtcacctgggtgcgggc
gtggacctggccgcggtgaacgcgcccggctcggtggtgctctccggtgacgaggaagcc
gtcgtggccgtcgccgagaaactgcgcgaacagggccgcagggtcaagcggctcaccgtc
tcgcacgccttccactcggcgctcatggagcccatgctcgccgacttcaccgccgccctg
tccgggctgacctggcacgaacccaccctccccgtcgtctccaacgtgacgggccgcctc
gccgaaccgggccggttgaccgaccccgcctactgggtcgaccacgtccgccgtcccgtc
cgcttcgccgacggcatcgccgcgtcgggcgggtcggtcttcctggaactcggccccggc
ggcgcgctgaccggcgcgatcgcccagtcggccggcgacgacgcggtcagcgtgcccgcc
ctgcgcgacgaccgcggcgaggcgcagaccctgctgctgtccgtcgcggagctgttcgtg
cgcggcacgaacgtgaactgggcggccgtcctccccgagggtgccaccgacgcccacgtg
gacctgccgacgtacgccttcgaccaccgccactactggctgcggatggctcccgccacc
gacgcggtcgccctgggccagggcacggcggaccacccgttgctgggtgcggtcgtggag
gtcccggagaccggcggggtgctgttcacctcccggctgtccctgcgcacccacccctgg
ctcgccgaccacgccgtgggcggtgtggtcctggtgcccggcaccgggctggtcgagctg
gccgtgcgggccggtgacgaggtcggcagcggagtgctggacgaactcgtcatcgaagca
ccgctggtcgtcccggaacacggcggtgtccgggtccaggtcgccgtcggcggccccgac
gacagcggactgcggaccgtctccgtctactcggcccgggagaacaccaccggcgagatc
gacaccgacgcctggacccggcacgccaccggcaccgtgacggcgtcggcggcggacaca
cccgccttcgacaccaccgtctggccgcccgccggagccgaacccgtcgacctcgacatc
accgccttctacacggacctgctgagccacggctacgcctacggcccggcgttccagggg
ctgcgcgcggtgtggcggcgcggcgaggagatcttcgccgaggtcgccctgccggacgaa
cagcgcgacgaggccgcacgcttcggcctccaccccgcactgctcgacgcggccctgcac
acggacgccttcgcccagccggacgacgggcacaacgtcctgccgttctcctggaacggg
ctggagctgcacgccgccggcgccgcgtccctccgggtacggatcaccccccgcggaacc
gacgcgctctccctggtcgcggccgacgagaacggcggtcttgtcctgaccgtcgactcg
gtgaccttccgcccggtggacgtcggacagctcgacgccgccgcgacggccggcgaggac
cgcgacgccctgttcaccgtcgcctggaccgacctccccgcaccggcctcgacgccggac
acggcccccgcgtgggcgcgggtcgccaccgcggccgaggtgaccgcgctgaggggcgag
gtgtccgaggccgccgtcctggacctccggggcaccggcgacggagacgaggagacgctc
acccggaccgccgccgccctggaggtcgtccaggcgtggctcgccgacgaggacgccgag
gacgcgcggctgctggtggtgacccggggcgcggtacccgcgggcggcgccgccacggtg
accgacgcggccggcgcggcggtctggggcctggtccgcgcggcccaggccgagaacccg
gaccgcatcgtcctgctcgacctggacccggccaccgacccggccaccgacgaaccgtcc
gacggcctcctcgccaccgtcctcgcctccggggagccgcaggtggcggtgcgggaggcg
gcgctgtcggtgccgcgcctggtgcgggcggagccttccgagggcgaacggtccgagggc
gagtcgagtgtgtcgttccgtccggggggtacggtcctggtgacgggcggtacgggttcg
ctcggtgcgctggtcgcccgtcatctggtcgtacggcacggggtacggcacctggtgctg
gccggccggcgcggcacggaggccgagggcgcgacggagctggtggccgaactgtccggc
ctgggcgccgagtcggtgtccctggtggccgccgacgtgtccgaccgtacccaggtggca
caactgctggagtccatcccggccgagcacccgctgacgggtgtggtccacacggcaggc
gtcctggacgacggcgtcatcggcgccctcaccccggaacgcctcgcccgggtcttcgca
cccaaggtcagcgcggtacagcacctcgacgagctgacccgcaccctggatctgaccgcg
ttcgccgtcttctcctccgcctccggcctgttcggctcggcgggccagggcaactacgcc
gccgccaacgcctacctcgacgcggtcgcccaccagcgccgggccgacggcctgcccgcc
acctcactcgcctggggcctctgggagcagaccagcggcatgaccgcccacctgggcgcc
gccgaccaggcccgcatgagccggggcggtgtcctgcccatcgcccccgccgagggcatg
cgcctcctcgacgcggccctggccaccgccgaagcactcctggtccccatcaagctcgac
ctgcgggccctgcgcgccgacgcggcagcgggccgcaccgtacagcccctgttgcgcggc
ctggtccgcaccggccgccaaccggtccgcaccaccgccggggacagcggcggcggcctc
acccgccggctcgccggactcgcccaggccgaacaggaggccctgctcctggacctcgtc
cgcggccaggtcgcgaccgtcctcggccacgccggggcggagaacgtgggccccgagacg
gccttcaaggacgccgggttcgactcactcacctccgtcgaactgcgcaaccggctccgc
gagaccaccgggctcaaactggccgccacggtcgtgttcgactaccccaacccgctcgct
ctggcccgccacctgcacacggaactgggcaccaccaacgacgccctgtcgctggtccac
gaaaagatcgaggacatcgactcgctgatcgccggactgctgtccgacgagtccaagaag
gcagacatcgtgctccgcctccagggcctggtcgcgaagtgcaacggagtggtcgaggag
acagagggttccgccgtggcggaacagctcgaatccgcctccgccgatgaggtcctcgac
ttcatcaacgacgaactcggaatctcctga
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