Streptomyces deccanensis: L3078_32280
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Entry
L3078_32280 CDS
T08215
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sdec
Streptomyces deccanensis
Pathway
sdec00290
Valine, leucine and isoleucine biosynthesis
sdec00660
C5-Branched dibasic acid metabolism
sdec01100
Metabolic pathways
sdec01110
Biosynthesis of secondary metabolites
sdec01210
2-Oxocarboxylic acid metabolism
sdec01230
Biosynthesis of amino acids
Module
sdec_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sdec00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
L3078_32280 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
L3078_32280 (leuC)
Enzymes [BR:
sdec01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
L3078_32280 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
L3078_32280 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ULR53581
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Position
7251990..7253420
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRKVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRANAAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPLVRPKTMAITVEGELAEGVTA
KDLILAIIAKIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDQTTF
DYLKGRPHAPEGEDWDAAVAYWKTLKTDDDAEFDAEVIIDGASLSPFVTWGTNPGQGAPL
SASVPDPASYEDASERLAAEKALEYMGLEAGQPLRSIKVDTVFVGSCTNGRIEDLRAAAE
LVKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLTDATAPAPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccccaggcc
ttcgacggtctccgcaagagcgggcggaaggttcgccggctcgacctgaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagcccatcgcggacccggtctcccgt
gtccagctggagacgctgcgcgcgaacgccgccgagttcggtgtgcgtctgcacccgctg
ggcgacgtcgagcagggtgtcgtgcacgtcgtcggcccgcagctgggtctgacccagccc
ggcatgacggtcgtctgcggtgactcccacacctcgacgcacggtgccttcggcggtctg
gcgttcggtatcggcacctcccaggtggagcacgtgctggccacgcagacgctgccgctg
gtccgccccaagaccatggcgatcacggtcgagggcgagctcgccgagggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaagatcggtacgggcggcggccagggctatgtc
ctggagtaccggggcgaagccatcgagaaactctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggtgcccgcgcgggcatgatcgcccccgaccagaccaccttc
gactacctcaagggtcgcccgcacgcccctgagggcgaggactgggacgcggccgtcgcg
tactggaagacgctgaagacggacgacgacgccgagttcgacgccgaggtgatcatcgac
ggcgcctccctgtcgccgttcgtgacctggggcaccaaccccggccagggcgcgccgctt
tcggcctcggtccccgacccggcttcgtacgaggacgcttcggagcgcctggccgccgaa
aaggccctggagtacatggggttggaggccggccagccgctgcgctccatcaaggtggac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgcgccgccgccgag
ctggtcaagggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctccgcg
cgggtcggtctgcaggccgtctccgagggcctggacgtcgtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgtctgggcatgaaccccgaccagctggccccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggcaggcagggcaagggcggc
cgtacccacctggtctccccgcaggtcgccgccgcgacggccgtcctcggccatctggcg
tcccccgccgacctgaccgacgccaccgcccccgcgcccgctggagtctga
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